The present invention provides a process for the preparation of 3-N-benzylidene derivative of betulinic acid, used for treatment of angiogenesis, said process comprising the steps of dissolving 3-amino derivative of betulinic acid in an alcoholic solvent to obtain a solution, adding a benzaldehyde reagent the presence of an alkali carbonate to this solution, stirring, removing the solvent under vacuum, adding water and a halogenated organic solvent to the product, and separating the organic layer from the aqueous layer by conventional methods and evaporating the organic layer to obtain 3-N-benzylidene derivative of betulinic acid.
| # | Name | Date |
|---|---|---|
| 1 | 2195-del-98-petition-123.pdf | 2011-08-21 |
| 2 | 2195-del-98-gpa.pdf | 2011-08-21 |
| 3 | 2195-del-98-form-3.pdf | 2011-08-21 |
| 4 | 2195-del-98-form-2.pdf | 2011-08-21 |
| 5 | 2195-del-98-form-1.pdf | 2011-08-21 |
| 6 | 2195-del-98-description (complete).pdf | 2011-08-21 |
| 7 | 2195-del-98-correspondence-po.pdf | 2011-08-21 |
| 8 | 2195-del-98-correspondence-others.pdf | 2011-08-21 |
| 9 | 2195-del-98-claims.pdf | 2011-08-21 |
| 10 | 2195-del-98-abstract.pdf | 2011-08-21 |