The present invention relates to a process for synthesis of pregabalin. More particularly, the present invention relates to an improved process for synthesis of S (+) pregabalin in high yield and high optical purity.
Racemic 2-pipecoloxylidide is dissolved in lsopropyl alcohol, filtered through hiflow bed and washed twice ipa, filterd; residue is washed thrice with iph to gey dry solid dibenzoyl-2-pipecolinoxylidide-l-tartrte which is dissolved in water and toluence, heated and caustic lye is added, stirred to get two layers, fo...
Glycine is added to Methanolic Sodiumhydroxide solution at 30-35ÂșC followed by addition of Methylpentanimidate, from which Methanol is distilled out, residue is treated with Toluene, Phosphorous oxychloride and N, N- dimethyl formamide, this mixture is quenched in cold water; Hi-flow is added and pH is adjusted to 1...
The invention relates to a process for the preparation of a quaternary ammonium hydroxide, in particular denatonium hydroxide, and the use thereof for the preparation of a quaternary ammo nium salt, in particular of denatonium benzoate or a denatonium fatty acid derivative. Due to its extremely bitter taste, th...
The invention relates to a preparation process for 2-substituted 5-formylimidazoles, wherein the intermediate high-pressurized synthesis of an 2-substituted 4-hydroxymethylimidazole as known in the art is conveniently avoided, and wherein much higher yields are obtained. Instead, it is proposed to prepare such 2-sub...
The invention relates to a process for the preparation of a quaternary ammonium hydroxide, in particular denatonium hydroxide, and the use thereof for the preparation of a quaternary ammonium salt, in particular denatonium benzoate. Due to its extremely bitter taste, this latter compound is applied in the art as an ...
The invention pertains to a process for preparing stable anhydrous Ropivaeaine hydrochloride, the process involving preparing Ropivaeaine hydrochloride from Ropivaeaine base, wherein Ropivaeaine base is provided having a chiral purity of more than 95 %. and wherein the isolation involves the use of isopropanol and h...
The present invention relates to an improved process for preparation of cinacalcet hydrochloride with high yields. In particular, the present
invention relates to an improved in-situ process for preparation of
cinacalcet hydrochloride with high yield and purity without isolation of
intermediates.
...
The present invention involves an improved process for the preparation of Indocyanine green of Formula (I) having high purity of about 99% wherein the process comprises steps of reacting 112-trimethyl-1H-benzo[e]indole with 14-butane sulfone in boiling solvent to give 4-(112-trimethyl-1H-benzo[e]indolium-3-yl)butane...
The present invention relates to an improved method for preparation and purification of atovaquone and its intermediate product. The present invention claims for an improved method for preparation and purification of the intermediate trans-2-[4-(4-chlorophenyl)cyclohexyl]-3-chloro-l,4-naphthoquinone(II) of formula-I...
[Class : 5] Ayurvedic; Medicinal And Pharmaceuticals Preparations; Veterinary And Sanitary Preparations, Dietetic Substances Adapted For Medical Use Food For Babies, Plasters Materials For Dressings, Material For Stopping Teeth, Dental Wax, Disinfectants, Preparations For Destroying Vermin, Fungicides, Herbicides
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[Class : 1] Chemicals Used In Industry, Science And Photography, As Well As In Agriculture, Horticulture And Forestry; Unprocessed Artificial Resins, Unprocessed Plastics; Manures; Fire Extinguishing Compositions; Tempering And Soldering Preparations; Chemical Substances For Preserving Foodstuffs; Tanning Substances;Adhesives Used In Industry
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