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An Improved Process For The Preparation Of Indocyanine Green

Abstract: The present invention involves an improved process for the preparation of Indocyanine green of Formula (I) having high purity of about 99% wherein the process comprises steps of reacting 112-trimethyl-1H-benzo[e]indole with 14-butane sulfone in boiling solvent to give 4-(112-trimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate. Followed by reacting 4-(112-trimethyl-1H-benzo[e]indolium-3-yl)butane-1-sulfonate of Formula (IV) and N-phenyl-N-((1E3E5E)-5-(phenylimino)penta-13-dienyl)acetamide of formula (V) in presence of sodium acetate and alcohol; and extracting the title compound formula (I) with an ester solvent.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
01 June 2018
Publication Number
36/2018
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2023-12-04
Renewal Date

Applicants

DISHMAN PHARMACEUTICALS AND CHEMICALS LIMITED
Survey No. 47, Paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220

Inventors

1. VYAS, Janmejay, Rajnikant
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220
2. DHOTRE, Himani
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220
3. SARMA, Narasimha
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220
4. PATEL, Babulal, R.
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220
5. SHARMA, Dinesh, Kumar
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220
6. PATEL, Dilip, N.
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220
7. SONI, Ashish, A.
Dishman Pharmaceuticals and Chemicals Limited Survey No 47, paiki Sub Plot No. 1 Village, Lodariyal Taluka – Sanand Gujarat Ahmedabad 382220

Specification

Documents

Orders

Section Controller Decision Date

Application Documents

# Name Date
1 201827020669-IntimationOfGrant04-12-2023.pdf 2023-12-04
1 201827020669-STATEMENT OF UNDERTAKING (FORM 3) [01-06-2018(online)].pdf 2018-06-01
2 201827020669-PatentCertificate04-12-2023.pdf 2023-12-04
2 201827020669-PRIORITY DOCUMENTS [01-06-2018(online)].pdf 2018-06-01
3 201827020669-Written submissions and relevant documents [29-11-2023(online)].pdf 2023-11-29
3 201827020669-FORM 1 [01-06-2018(online)].pdf 2018-06-01
4 201827020669-DRAWINGS [01-06-2018(online)].jpg 2018-06-01
4 201827020669-Correspondence to notify the Controller [13-11-2023(online)].pdf 2023-11-13
5 201827020669-US(14)-HearingNotice-(HearingDate-14-11-2023).pdf 2023-10-13
5 201827020669-DECLARATION OF INVENTORSHIP (FORM 5) [01-06-2018(online)].pdf 2018-06-01
6 201827020669-FORM 3 [05-06-2023(online)].pdf 2023-06-05
6 201827020669-COMPLETE SPECIFICATION [01-06-2018(online)].pdf 2018-06-01
7 201827020669-FORM-26 [02-07-2018(online)].pdf 2018-07-02
7 201827020669-FORM 3 [28-12-2022(online)].pdf 2022-12-28
8 201827020669.pdf 2018-08-11
8 201827020669-CLAIMS [24-11-2021(online)].pdf 2021-11-24
9 201827020669-FER_SER_REPLY [24-11-2021(online)].pdf 2021-11-24
9 Abstract1.jpg 2018-09-05
10 201827020669-FORM 3 [28-09-2018(online)].pdf 2018-09-28
10 201827020669-OTHERS [24-11-2021(online)].pdf 2021-11-24
11 201827020669-FER.pdf 2021-10-18
11 201827020669-FORM 3 [12-10-2018(online)].pdf 2018-10-12
12 201827020669-FORM 3 [23-04-2021(online)].pdf 2021-04-23
12 201827020669-Proof of Right (MANDATORY) [01-12-2018(online)].pdf 2018-12-01
13 201827020669-FORM 3 [23-10-2020(online)].pdf 2020-10-23
13 201827020669-ORIGINAL UR 6(1A) FORM 26-100718.pdf 2019-01-11
14 201827020669-FORM 3 [25-09-2020(online)].pdf 2020-09-25
14 201827020669-ORIGINAL UR 6(1A) ASSIGNMENT-051218.pdf 2019-04-30
15 201827020669-FORM 3 [08-05-2019(online)].pdf 2019-05-08
15 201827020669-FORM 3 [11-03-2020(online)].pdf 2020-03-11
16 201827020669-FORM 3 [04-01-2020(online)].pdf 2020-01-04
16 201827020669-FORM 3 [29-06-2019(online)].pdf 2019-06-29
17 201827020669-FORM 18 [04-11-2019(online)].pdf 2019-11-04
18 201827020669-FORM 3 [29-06-2019(online)].pdf 2019-06-29
18 201827020669-FORM 3 [04-01-2020(online)].pdf 2020-01-04
19 201827020669-FORM 3 [08-05-2019(online)].pdf 2019-05-08
19 201827020669-FORM 3 [11-03-2020(online)].pdf 2020-03-11
20 201827020669-FORM 3 [25-09-2020(online)].pdf 2020-09-25
20 201827020669-ORIGINAL UR 6(1A) ASSIGNMENT-051218.pdf 2019-04-30
21 201827020669-FORM 3 [23-10-2020(online)].pdf 2020-10-23
21 201827020669-ORIGINAL UR 6(1A) FORM 26-100718.pdf 2019-01-11
22 201827020669-FORM 3 [23-04-2021(online)].pdf 2021-04-23
22 201827020669-Proof of Right (MANDATORY) [01-12-2018(online)].pdf 2018-12-01
23 201827020669-FER.pdf 2021-10-18
23 201827020669-FORM 3 [12-10-2018(online)].pdf 2018-10-12
24 201827020669-OTHERS [24-11-2021(online)].pdf 2021-11-24
24 201827020669-FORM 3 [28-09-2018(online)].pdf 2018-09-28
25 201827020669-FER_SER_REPLY [24-11-2021(online)].pdf 2021-11-24
25 Abstract1.jpg 2018-09-05
26 201827020669-CLAIMS [24-11-2021(online)].pdf 2021-11-24
26 201827020669.pdf 2018-08-11
27 201827020669-FORM 3 [28-12-2022(online)].pdf 2022-12-28
27 201827020669-FORM-26 [02-07-2018(online)].pdf 2018-07-02
28 201827020669-COMPLETE SPECIFICATION [01-06-2018(online)].pdf 2018-06-01
28 201827020669-FORM 3 [05-06-2023(online)].pdf 2023-06-05
29 201827020669-DECLARATION OF INVENTORSHIP (FORM 5) [01-06-2018(online)].pdf 2018-06-01
29 201827020669-US(14)-HearingNotice-(HearingDate-14-11-2023).pdf 2023-10-13
30 201827020669-Correspondence to notify the Controller [13-11-2023(online)].pdf 2023-11-13
30 201827020669-DRAWINGS [01-06-2018(online)].jpg 2018-06-01
31 201827020669-Written submissions and relevant documents [29-11-2023(online)].pdf 2023-11-29
31 201827020669-FORM 1 [01-06-2018(online)].pdf 2018-06-01
32 201827020669-PRIORITY DOCUMENTS [01-06-2018(online)].pdf 2018-06-01
32 201827020669-PatentCertificate04-12-2023.pdf 2023-12-04
33 201827020669-STATEMENT OF UNDERTAKING (FORM 3) [01-06-2018(online)].pdf 2018-06-01
33 201827020669-IntimationOfGrant04-12-2023.pdf 2023-12-04

Search Strategy

1 searchstrategy201827020669E_30-05-2021.pdf

ERegister / Renewals

3rd: 07 Feb 2024

From 29/11/2018 - To 29/11/2019

4th: 07 Feb 2024

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5th: 07 Feb 2024

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6th: 07 Feb 2024

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8th: 07 Feb 2024

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9th: 12 Nov 2024

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10th: 01 Nov 2025

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