12222The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt thereof wherein R is selected from methyl pyrrolidinyl optionally substituted with one or more of fluorine methyl and hydroxyl piperidinyl morpholinyl fluorobenzylazetidinyl methylamino substituted with one or more o...

ABSTRACT The present invention provides a mixture of adsorbents which has the capacity to adsorb high concentrations of antibiotics from a diverse range of classes, pathogens, and heavy metals. The invention is a mixture of various charcoal adsorbents including areca nut, bamboo, pine nut, coconut shell and paper t...

The present invention provides novel quinoline compounds or their pharmaceutically acceptable salts. The compounds of the invention efficacious in the treatment of Tuberculosis and other mycobacterial infections.

The present invention provides cyclic and acyclic derivatives of eugenol that exhibit antileishmanial activity against promastigote and amastigote forms of L. donovani.

The present invention provides novel compounds of benzimidazole derivatives as anti-tubercular agents and their pharmaceutically acceptable salts for use as bactericidal therapeutics.

The present invention provides shortening TB Therapy and reducing relapse by co-administering Chloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1. The present invention also provides shortening TB Therapy and reducing relapse ...

The present invention provides methods for treating malaria. The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising aN-hydroxy-4-((4-(4-(pyrrolidin-1-ylmethyl)phenyl)-1H-1,2,3-triazol-1-yl)methyl)benzamide...

Thiazolyl peptides for the treatment Nontuberculous Mycobacterial infections ABSTRACT The present invention provides novel thiazolyl peptide compounds and their pharmaceutically acceptable salts either alone or in combinations with Rifampicin, Amikacin and Clarithromycin against infections caused by Nontuberculo...

ABSTRACT NOVEL SUBSTITUTED QUINOLINE TRIAZOLE COMPOUNDS AND METHODS OF PREPARATION THEREOF The present invention relates to novel substituted quinoline triazole compounds of formula (1) or pharmaceutically acceptable salts thereof, which are useful in treating tuberculosis and other mycobacterial infections. W...

The present invention provides a compound Drotaverine for use in treating and/or preventing a coronavirus infection in a subject.

ABSTRACT The present invention provides novel synthetic flavonoid compounds that are active against severe acute respiratory syndrome-2 (SARS-CoV-2), Human respiratory syncytial virus, influenza A & B types, Chikungunya virus, Zika virus, , and Rabies. Furthermore, the invention relates to the compounds, their prep...

Abstract The present invention discloses a LAMP-based assay for the detection and diagnosis of Lymphatic Filariasis (LF) using novel gene targets. Leveraging advanced computational algorithms, the present invention provides comprehensive analysis of genomic, transcriptomic, and proteomic data, culminating in the sy...