A method is described for performing a binding assay, comprising the steps of: (i) bringing a target molecule into contact with its affinity partner to form a binding complex, wherein the target molecule is immobilised on a magnectic particle and the affinity partner is immobilised on a support material; and determi...

The present invention provides an in vitro method for determining the resistance or sensitivity of a cell line or patient sample to a deoxyribonucleoside kinase-dependent drug, wherein the method comprises the steps of: (i) treating a patient sample or cell line, or a portion thereof, with a deoxyribonucleoside kina...

An assay for measuring the amount of a first analyte in a sample, comprises the steps of: (i) contacting the sample with a device that comprises one or more first reaction sites which comprise a first ligand having affinity for the first analyte, and a series of second reaction sites each comprising different known ...

A diagnostic method is disclosed which can be used to predict the risk of cancer, in particular breast cancer. The method comprises: (i) isolating a sample of the patient's genome; and (ii) detecting the presence or expression of the gene comprised within the sequence identified herein as SEQ ID No. 1, wherein the p...

A solid state device for performing multi-analyte assays, comprises a substrate and a multiplicity of discrete reaction sites each bearing a ligand covalently bonded to the substrate, wherein the surface of the substrate between the reaction sites is inert with respect to analyte. Such a device may be obtained by a ...

An assay device processing instrument comprises a plurality of processing modules (10,13-19). A transport system (11,12) transports an assay device to each processing module, the transport system being adapted to transfer the assay device from the transport system to the module to enable the transport system to tran...

Assay deviee processing apparatus comprises a rotatably mounted assay device vessel support (58) and a drive (42) for rotating the support. The support (58) is rotatable about a substantially horizontal first axis so that, upon rotation, an assay device vessel attached to the support can be Inverted ...

A diagnostic method is disclosed which can be used to predict the risk of cancer in particular breast cancer. The method comprises: (i) isolating a biological sample from a patient; and (ii) detecting the presence or expression of the gene comprised within the sequence identified herein as SEQ ID No. (1), wherein th...

A substrate comprising a coating of a masking material and a plurality of discrete reaction zones onto which one or more binding agents are intended to be attached wherein said zones are uncoated areas on the substrate.