The present invention relates to a pharmaceutical composition for the treatment of an infection in an animal comprising an antibiotic or one of its pharmaceutically stable salts; an antifungally effective amount of a pharmaceutically acceptable triazole compound, a corticosteroid and at least one pharmaceutically ac...

A process for preparing ester oxazolidine compounds is disclosed. These compounds are useful intermediates in processes for making Florfenicol.

An improved method of preparing oxazolidine protected aminodiol compounds is disclosed. These compounds are useful intermediates in processes for making Florfenicol.

An improved method of preparing oxazolidine protected aminodiol compounds is disclosed. These compounds are useful intermediates in processes for making Florfenicol.

Novel trifluoromethanesulfonanilide oxime ether compounds useful for controlling endo and/or ectoparasites in the environment are provided, together with methods of making the same, and methods of using the inventive compounds to treat parasite infestations in vivo or ex vivo.

A method of providing systemic analgesia to cats, dogs and other small mammals by the otic or transdermal administration of opioids is disclosed. Compositions for use in such, a method are also disclosed.

Abstract METHOD FOR REPLICATING INFLUENZA VIRUS IN CULTURE The invention is related to a method for selecting an influenza virus for growth on tissue culture cells to produce to tissue-cultural adapted viral isolate. The invention also includes vaccines produced from the isolate.

Abstract CANINE THYMIC STROMAL LYMPHOPOIETIN PROTEIN AND USES THEREOF The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and rela...

Abstract EFFERVESCENT FORMULATIONS OF FLORFENICOL FOR ADDITION IN DRINKING WATER SYSTEMS The invention relates to an effervescent formulation containing florfenicol or an antibiotic of related structure. When introduced into water, the effervescent formulation s dissolved with minimal or no agitation and provides ...

Abstract PHARMACEUTICAL COMPOSITIONS AND METHOD FOR TREATING INFLAMMATION IN CATTLE AND OTHER ANIMALS Novel transdermal preparations combining a non-steroidal anti¬inflammatory drug (NSAID) such as flunixin, are disclosed. Methods for using and administering such preparation in the treatment of inflammatory condit...

The present invention discloses phosphate esters of florfenicol (prodrugs) and florfenicol analogs having superior water solubility that are hydrolyzed to florfenicol or the respective florfenicol analog in vivo, upon administration to an animal.

Novel formulations combining an antiparasitic compounds, such as an avermectin, with a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as Florfenicol are disclosed. Methods for using such formulations in the treatment and prevention of infectious diseases of bovines and swine, including bov...

ABSTRACT The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of tre...

The present invention relates to a novel fonnulation combining a non-steroidal anti-inflammatory drug (NSAID) such as flunixin, v"ith a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as florfenicol as disclosed. Methods for using such fonnulations in the treatment and prevention of infectiou...

The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating anim...

Novel imidazo[1,2-b]pyridazine compounds useful for controlling parasites in animals and methods of treatment of parasite infestation in animals using the compounds are disclosed. Formula (I).

A method of preparing oxazoline-protected aminodiol compounds of formula IV is disclosed. These compounds are useful intermediates in processes for preparing Florfenicol and related compounds.

A parasiticidal composition The present invention relates to a parasiticidal composition for topical application to an animal consisting essentially of a pyrethroid or a pyrethrin and a carrier; wherein said carrier is selected from the group consisting of a terpene, a terpene derivative, a terpene with an alkyl gl...

The present invention relates to novel formulations combining an antiparasitic compounds, such as avermectin, with a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as Flofenicol are disclosed. Methods for using such formulations in the treatment and prevention of infectious diseases of bovin...

Abstract RECOMBINANT ATTENUATED CLOSTRIDIUM ORGANISMS AND VACCINE The present invention discloses attenuated Clostridium perfringens organisms that express a substantially nontoxic alpha-toxin. The expressed alpha-toxin is a deletion mutein that relative to the alpha-toxin of the mature alpha-toxin of Clostridi...

The invention relates to carbonate derivatives of fenicol compounds of formulae I and II, wherein the variables are as defined in the claims, having useful properties as antibiotic prodrugs, together with methods of making and using these compounds.

The invention relates to a method of excysting and growing protozoal oocysts by in vitro tissue culture resulting in production of a continuous culture of merozoites. The invention also provides an economical and reliable supply of cultured Eimeria sp. for vaccine production, assays and research. Domesticated avians...