The present invention relates to a method for obtaining master adult pluripotent stem (MAPS) cells from adult human corneal epithelial tissues. The MAPS cells are obtained on the basis of pluripotent markers. Futher the invention provides MAPS cells that are capable of self renewal and differentiation and have chara...

The present disclosure relates to a method of preparing stromal cell based compositions. The said compositions comprise pooled cells which are arrived by pooling of cells from individual donors. Said pooling of cells is based on the analysis of characteristics such as but not limiting to growth kinetics, gender, imm...

Present disclosure discloses a robust manufacturing process for consistent production of clinical grade Mesenchymal Stromal cells (MSCs). The process enables production of highly viable potent cells. The process steps relating to preparation of media, cell seeding, harvesting are fine tuned to achieve consistency in...

The present disclosure discloses methods of isolating, culturing and pooling of Wharton"s jelly derived cells to obtain a composition of pooled allogeneic mesenchymal stem cells (MSCs). The method comprises of collecting umbilical cords from multiple donors followed by isolation, culturing and pooling of WJ-MSCs fro...

The present disclosure relates to cryopreservation of cells. In particular, a cryopreservation composition/formulation for preserving cells and corresponding methods are provided. The said xenofree and low concentration cryopreservant containing composition is an improved and efficient composition/formulation which ...

“MULTI PLANE MIXER AND SEPARATOR (MPMS) SYSTEM” ABSTRACT The present disclosure provides a multi plane mixer and separator (MPMS) system. The system comprises a base frame of predetermined shape configured to form a base for the MPMS system. A motor is mounted to the base frame for rotating the MPMS system. A ba...

The present disclosure relates to a method for isolating and culturing adipose tissue-derived mesenchymal stromal/stem cells (ASC) by explant culture method. The adipose tissue obtained by surgical or other known method is processed to isolate a enriched population of MSC more economically. The multipotent ASC so ob...

The present invention relates to the field of stem cells particularly development of a novel human embryonic model using human embriod bodies obtained form the human embryonie stem cell.The novel human embryonic model disclosed thus can provide a screening assay for determining the toxic activity of the compound and...

The present invention provides a process of isolation, proliferation and/or maintenance of mesenchymal stem cells (MSCs).The invention further provides a culture medium for proliferation and/or maintenance of human mesenchymal stem cells in xeno-free conditions.The culture medium provides provided in the present inv...

The present disclosure provides novel culture system and methods for culturing and propagating hESCs in a substantially undifferentiated state for several passages. The ability to grow such cells without differentiation has important applications for therapeutic uses of ES cells for treating human disorders using ti...

The present disclosure relates to the human germ layer derived feeder cells (GLDF cells) and method of generation thereof. Further, it relates to a method for culturing and propagating human embryonic stem cells (hESCs) in a substantially undifferentiated state for several passages on the human GLDF cells. The abili...

The present invention relates to gold nanoparticle (GNP) and a method to perpetuate stemness of stem cells comprising step of growing the stem cells in presence of gold particle or Swama Bhasma. It also relates to compositions for perpetuating stemness of stem cells.

The present invention discloses a method of isolation, pooling and further culturing of Mesenchymal Stem cells (MSC) for clinical application. Present invention also discloses the method of establishing Master Cell bank, followed by Working Cell Bank from which the final therapeutic composition referred to as Invest...

The present disclosure provides an automated system for isolating stromal vascular fraction cells from the mammalian tissue. The system comprises a plurality of containers for storing buffer solutions, tissue samples and digestive buffers. A tissue processing unit fluidly connected to the containers for processing t...

The present disclosure relates to an ultrasound guided intraarticular administration of a combination of a composition comprising pooled mesenchymal stromal cells, and mid molecular weight hyaluronic acid for treatment of osteoarthritis. The disclosure also provides methods for increasing levels of anti-inflammat...