Perfusion Culture Method

Abstract: Provided is a perfusion culture method, etc. enabling improvement of productivity in the manufacture of recombinant proteins. Specifically, provided is a method, etc. for enhancing production of recombinant proteins in a perfusion culture of animal cells that have a recombinant protein producing capability, the method including the addition of cystine and/or ammonium ferric citrate to the cell culture medium.

Patent Information

Application #

Filing Date

16 September 2024

Publication Number

2/2025

Publication Type

INA

Invention Field

BIO-CHEMISTRY

Status

Email

Parent Application

Applicants

AJINOMOTO CO., INC.

15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315

Inventors

1. TAKAO, Nobumasa

c/o Chugai Seiyaku Kabushiki Kaisha, 5-1, Ukima 5-chome, Kita-ku, Tokyo 1158543

2. HIGUCHI, Takuya

c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681

3. FUROMITSU, Shumpei

c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681

Specification

Documents

Application Documents

#	Name	Date
1	202447069905-STATEMENT OF UNDERTAKING (FORM 3) [16-09-2024(online)].pdf	2024-09-16
2	202447069905-REQUEST FOR EXAMINATION (FORM-18) [16-09-2024(online)].pdf	2024-09-16
3	202447069905-PROOF OF RIGHT [16-09-2024(online)].pdf	2024-09-16
4	202447069905-PRIORITY DOCUMENTS [16-09-2024(online)].pdf	2024-09-16
5	202447069905-FORM 18 [16-09-2024(online)].pdf	2024-09-16
6	202447069905-FORM 1 [16-09-2024(online)].pdf	2024-09-16
7	202447069905-DRAWINGS [16-09-2024(online)].pdf	2024-09-16
8	202447069905-DECLARATION OF INVENTORSHIP (FORM 5) [16-09-2024(online)].pdf	2024-09-16
9	202447069905-COMPLETE SPECIFICATION [16-09-2024(online)].pdf	2024-09-16
10	202447069905-FORM-26 [18-09-2024(online)].pdf	2024-09-18
11	202447069905-FORM 3 [03-02-2025(online)].pdf	2025-02-03