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Compositions And Methods For Inhibiting Transmembrane Serine Protease 6 (Tmprss6) Expression

Abstract: Oligonucleotides are provided herein that inhibit TMPRSS6 expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with hepcidin deficiency or suppression. 5

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Patent Information

Application #
Filing Date
08 January 2025
Publication Number
03/2025
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
Parent Application

Applicants

NOVO NORDISK A/S
Novo Allé 1 2880 Bagsværd
DICERNA PHARMACEUTICALS INC.
75 Hayden Avenue Lexington, Massachusetts 02421

Inventors

1. BLOIS, Anna, Linda
75 Hayden Avenue Lexington, Massachusetts 02421
2. PRIEST, Christina Marie
75 Hayden Avenue Lexington, Massachusetts 02421
3. PARK, Jihye
75 Hayden Avenue Lexington, Massachusetts 02421
4. DUDEK, Henryk
75 Hayden Avenue Lexington, Massachusetts 02421

Specification

Documents

Application Documents

# Name Date
1 202547001692-STATEMENT OF UNDERTAKING (FORM 3) [08-01-2025(online)].pdf 2025-01-08
3 202547001692-Sequence Listing in PDF [08-01-2025(online)].pdf 2025-01-08
4 202547001692-PROOF OF RIGHT [08-01-2025(online)].pdf 2025-01-08
5 202547001692-PRIORITY DOCUMENTS [08-01-2025(online)].pdf 2025-01-08
6 202547001692-POWER OF AUTHORITY [08-01-2025(online)].pdf 2025-01-08
7 202547001692-FORM 1 [08-01-2025(online)].pdf 2025-01-08
8 202547001692-FIGURE OF ABSTRACT [08-01-2025(online)].pdf 2025-01-08
9 202547001692-DRAWINGS [08-01-2025(online)].pdf 2025-01-08
10 202547001692-DECLARATION OF INVENTORSHIP (FORM 5) [08-01-2025(online)].pdf 2025-01-08
11 202547001692-COMPLETE SPECIFICATION [08-01-2025(online)].pdf 2025-01-08
12 202547001692-FORM 18 [09-01-2025(online)].pdf 2025-01-09
13 202547001692-FORM 3 [07-07-2025(online)].pdf 2025-07-07
14 202547001692-PA [22-09-2025(online)].pdf 2025-09-22
15 202547001692-ASSIGNMENT DOCUMENTS [22-09-2025(online)].pdf 2025-09-22
16 202547001692-8(i)-Substitution-Change Of Applicant - Form 6 [22-09-2025(online)].pdf 2025-09-22