Stat3 Targeting Oligonucleotides And Uses Thereof

Abstract: The subject matter disclosed herein is directed to modulating STAT3 gene expression using siRNA compositions and methods directed to affecting key cell populations supporting the growth and metastasis of cancer to affect the beneficial treatment, remission or removal of the underlying tumor in a patient.

Patent Information

Application #

Filing Date

13 June 2025

Publication Number

26/2025

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

NOVO NORDISK A/S

Novo Alle 1 2880 Bagsvaerd

Inventors

1. ABRAMS, Marc

c/o Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, Massachusetts 02421

2. DUDEK, Henryk T.

c/o Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, Massachusetts 02421

3. KRISHNAN, Harini Sivagurunatha

c/o Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, Massachusetts 02421

4. GANESH, Shanthi

c/o Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, Massachusetts 02421

Specification

Documents

Application Documents

#	Name	Date
1	202547057118-STATEMENT OF UNDERTAKING (FORM 3) [13-06-2025(online)].pdf	2025-06-13
3	202547057118-Sequence Listing in PDF [13-06-2025(online)].pdf	2025-06-13
4	202547057118-PRIORITY DOCUMENTS [13-06-2025(online)].pdf	2025-06-13
5	202547057118-POWER OF AUTHORITY [13-06-2025(online)].pdf	2025-06-13
6	202547057118-FORM 18 [13-06-2025(online)].pdf	2025-06-13
7	202547057118-FORM 1 [13-06-2025(online)].pdf	2025-06-13
8	202547057118-DRAWINGS [13-06-2025(online)].pdf	2025-06-13
9	202547057118-DECLARATION OF INVENTORSHIP (FORM 5) [13-06-2025(online)].pdf	2025-06-13
10	202547057118-COMPLETE SPECIFICATION [13-06-2025(online)].pdf	2025-06-13
11	202547057118-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [13-06-2025(online)].pdf	2025-06-13