Method For Secretory Production Of Proteins

Abstract: The present invention addresses the problem of developing a novel technology for improving the secretory production of heterologous proteins by coryneform bacteria and providing a method for the secretory production of heterologous proteins. Coryneform bacteria that have been modified such as to be capable of performing secretory production of heterologous proteins and to have reduced Mdh protein activity are cultured for secretory production of heterologous proteins.

Patent Information

Application #

Filing Date

11 September 2025

Publication Number

40/2025

Publication Type

INA

Invention Field

BIO-CHEMISTRY

Status

Email

Parent Application

Applicants

AJINOMOTO CO., INC.

15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315

Inventors

1. NAGASE, Yumi

c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681

2. MATSUDA, Yoshihiko

c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681

Specification

Documents

Application Documents

#	Name	Date
1	202547086540-STATEMENT OF UNDERTAKING (FORM 3) [11-09-2025(online)].pdf	2025-09-11
3	202547086540-Sequence Listing in PDF [11-09-2025(online)].pdf	2025-09-11
4	202547086540-REQUEST FOR EXAMINATION (FORM-18) [11-09-2025(online)].pdf	2025-09-11
5	202547086540-PROOF OF RIGHT [11-09-2025(online)].pdf	2025-09-11
6	202547086540-PRIORITY DOCUMENTS [11-09-2025(online)].pdf	2025-09-11
7	202547086540-FORM 18 [11-09-2025(online)].pdf	2025-09-11
8	202547086540-FORM 1 [11-09-2025(online)].pdf	2025-09-11
9	202547086540-DRAWINGS [11-09-2025(online)].pdf	2025-09-11
10	202547086540-DECLARATION OF INVENTORSHIP (FORM 5) [11-09-2025(online)].pdf	2025-09-11
11	202547086540-COMPLETE SPECIFICATION [11-09-2025(online)].pdf	2025-09-11
12	202547086540-Proof of Right [12-09-2025(online)].pdf	2025-09-12
13	202547086540-FORM-26 [12-09-2025(online)].pdf	2025-09-12