Compositions And Methods For Inhibiting Mitochondria Amidoxime

Compositions And Methods For Inhibiting Mitochondria Amidoxime Reducing Component 1 (Marc1) Expression

Abstract: Oligonucleotides are provided herein that inhibit MARC1 expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with MARC1 expression.

Patent Information

Application #

Filing Date

18 December 2023

Publication Number

02/2024

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

NOVO NORDISK A/S

Novo Allé 2880 Bagsværd

DICERNA PHARMACEUTICALS, INC.

75 Hayden Avenue Lexington, 02421

Inventors

1. DUDEK, Henryk

Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, MA02421

2. HAN, Wen

Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, MA02421

3. PURSELL, Natalie, Wayne

Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, MA02421

4. LAI, Chengjung

Dicerna Pharmaceuticals, Inc. 75 Hayden Avenue Lexington, MA02421

5. HAYNES, William, Geoffrey

Novo Nordisk Ltd. Old Road Campus Roosevelt Drive Oxford OX3 7FZ

6. DING, Zhihao

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road Beijing, Beijing 102206

Specification

Documents

Application Documents

#	Name	Date
1	202347086505-STATEMENT OF UNDERTAKING (FORM 3) [18-12-2023(online)].pdf	2023-12-18
2	202347086505-Sequence Listing in txt [18-12-2023(online)].txt	2023-12-18
3	202347086505-Sequence Listing in PDF [18-12-2023(online)].pdf	2023-12-18
4	202347086505-PRIORITY DOCUMENTS [18-12-2023(online)].pdf	2023-12-18
5	202347086505-POWER OF AUTHORITY [18-12-2023(online)].pdf	2023-12-18
6	202347086505-FORM 1 [18-12-2023(online)].pdf	2023-12-18
7	202347086505-DRAWINGS [18-12-2023(online)].pdf	2023-12-18
8	202347086505-DECLARATION OF INVENTORSHIP (FORM 5) [18-12-2023(online)].pdf	2023-12-18
9	202347086505-COMPLETE SPECIFICATION [18-12-2023(online)].pdf	2023-12-18
10	202347086505-FORM 18 [21-12-2023(online)].pdf	2023-12-21
11	202347086505-Proof of Right [04-06-2024(online)].pdf	2024-06-04