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Compositions And Methods For Inhibiting Nuclear Receptor Subfamily 1 Group H Member 3 (Nr1 H3) Expression

Abstract: Oligonucleotides are provided herein that inhibit NR1H3 expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with NR1H3 expression.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
10 November 2023
Publication Number
50/2023
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

NOVO NORDISK A/S
Novo Allé 2880 Bagsværd
DICERNA PHARMACEUTICALS, INC.
75 Hayden Avenue Lexington, Massachusetts 02421

Inventors

1. SAXENA, Utsav
75 Hayden Avenue Lexington, MA02421
2. DUDEK, Henryk
75 Hayden Avenue Lexington, MA02421
3. PURSELL, Natalie, Wayne
75 Hayden Avenue Lexington, MA02421
4. SPIEGELMAN, Nicole, Alexis
75 Hayden Avenue Lexington, MA02421
5. LATTA, Markus, Robert
NOVO NORDISK A/S Novo Allé 2880 Bagsværd
6. ANDERSEN, Birgitte
NOVO NORDISK A/S Novo Allé 2880 Bagsværd

Specification

Documents

Application Documents

# Name Date
1 202347076827-STATEMENT OF UNDERTAKING (FORM 3) [10-11-2023(online)].pdf 2023-11-10
2 202347076827-Sequence Listing in txt [10-11-2023(online)].txt 2023-11-10
3 202347076827-Sequence Listing in PDF [10-11-2023(online)].pdf 2023-11-10
4 202347076827-PRIORITY DOCUMENTS [10-11-2023(online)].pdf 2023-11-10
5 202347076827-POWER OF AUTHORITY [10-11-2023(online)].pdf 2023-11-10
6 202347076827-FORM 18 [10-11-2023(online)].pdf 2023-11-10
7 202347076827-FORM 1 [10-11-2023(online)].pdf 2023-11-10
8 202347076827-FIGURE OF ABSTRACT [10-11-2023(online)].pdf 2023-11-10
9 202347076827-DRAWINGS [10-11-2023(online)].pdf 2023-11-10
10 202347076827-DECLARATION OF INVENTORSHIP (FORM 5) [10-11-2023(online)].pdf 2023-11-10
11 202347076827-COMPLETE SPECIFICATION [10-11-2023(online)].pdf 2023-11-10
12 202347076827-Proof of Right [15-03-2024(online)].pdf 2024-03-15
13 202347076827-RELEVANT DOCUMENTS [29-07-2025(online)].pdf 2025-07-29