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Compound Or Salt Thereof, And Antibody Obtained Using Same

Abstract: The present invention pertains to a technique for controlling the bonding ratio of an antibody and a modified group to a desired range. More specifically, the present invention pertains to: a compound represented by formula (I) [in the formula, X represents a leaving group, Y represents an affinity peptide having a bonding site in a CH2 domain in an immunoglobulin unit including two heavy chains and two light chains, M represents a trivalent group that links a carbon atom in C=O and a carbon atom in C=W, which are adjacent to M, through a main chain portion composed of 3-5 carbon atoms, O represents an oxygen atom, S represents a sulfur atom, W represents an oxygen atom or a sulfur atom, N3 represents an azido group, La represents a bond or a divalent group, and Lb represents a bond or a divalent group] or a salt thereof; and an antibody or a salt thereof, which can be produced using said compound or salt thereof.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
07 September 2023
Publication Number
40/2023
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application

Applicants

AJINOMOTO CO., INC.
15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315

Inventors

1. FUJII, Tomohiro
c/o Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
2. YAMADA, Kei
c/o Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
3. MATSUDA, Yutaka
c/o Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
4. HIRAMA, Ryusuke
c/o Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
5. HATADA, Noriko
c/o Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
6. ARASHIDA, Naoko
c/o Ajinomoto Co., Inc., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681

Specification

Documents

Application Documents

# Name Date
1 202347060167-STATEMENT OF UNDERTAKING (FORM 3) [07-09-2023(online)].pdf 2023-09-07
2 202347060167-Sequence Listing in txt [07-09-2023(online)].txt 2023-09-07
3 202347060167-Sequence Listing in PDF [07-09-2023(online)].pdf 2023-09-07
4 202347060167-PRIORITY DOCUMENTS [07-09-2023(online)].pdf 2023-09-07
5 202347060167-FORM 1 [07-09-2023(online)].pdf 2023-09-07
6 202347060167-DRAWINGS [07-09-2023(online)].pdf 2023-09-07
7 202347060167-DECLARATION OF INVENTORSHIP (FORM 5) [07-09-2023(online)].pdf 2023-09-07
8 202347060167-COMPLETE SPECIFICATION [07-09-2023(online)].pdf 2023-09-07
9 202347060167-FORM 3 [30-10-2023(online)].pdf 2023-10-30
10 202347060167-FORM-26 [01-11-2023(online)].pdf 2023-11-01
11 202347060167-Proof of Right [26-12-2023(online)].pdf 2023-12-26
12 202347060167-RELEVANT DOCUMENTS [11-03-2025(online)].pdf 2025-03-11
13 202347060167-MARKED COPIES OF AMENDEMENTS [11-03-2025(online)].pdf 2025-03-11
14 202347060167-FORM 18 [11-03-2025(online)].pdf 2025-03-11
15 202347060167-FORM 13 [11-03-2025(online)].pdf 2025-03-11
16 202347060167-AMMENDED DOCUMENTS [11-03-2025(online)].pdf 2025-03-11