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Double Acylated Glp 1 Derivatives
Abstract: The invention relates to a derivative of a GLP-1 analogue which analogue comprises a first K residue at a position corresponding to position 37 of GLP-1(7-37) (SEQ ID NO: 1) a second K residue at a position corresponding to position 26 of GLP-1(7-37) and a maximum of ten amino acid modifications as compared to GLP-1(7-37) wherein the first K residue is designated K37 and the second K residue is designated K26 which derivative comprises two albumin binding moieties attached to K26 and K37. The invention also relates to the pharmaceutical use thereof for example in the treatment and/or prevention of all forms of diabetes and related diseases as well as to corresponding novel peptides and side chain intermediates. The derivatives are suitable for oral administration.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
14 June 2012
Publication Number
43/2013
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application
Patent Number
Legal Status
Grant Date
2019-02-27
Renewal Date
Applicants
Novo Nordisk A/S
Novo Allé DK-2880 Bagsværd
Denmark
Inventors
1. GARIBAY Patrick William
Novo Allé DK-2880 Bagsværd
Denmark
2. SPETZLER Jane
Novo Allé DK-2880 Bagsværd
Denmark
3. KODRA János Tibor
Novo Allé DK-2880 Bagsværd
Denmark
4. LINDEROTH Lars
Novo Allé DK-2880 Bagsværd
Denmark
5. LAU Jesper
Novo Allé DK-2880 Bagsværd
Denmark
6. SAUERBERG Per
Novo Allé DK-2880 Bagsværd
Denmark
Specification
ATTACHED
Documents
Orders
| Section | Controller | Decision Date |
|---|---|---|
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | Translation-Search Report.pdf | 2012-06-26 |
| 2 | Priority Document.pdf | 2012-06-26 |
| 3 | Form-5.pdf | 2012-06-26 |
| 4 | Form-3.pdf | 2012-06-26 |
| 5 | Form-1.pdf | 2012-06-26 |
| 6 | 5197-CHENP-2012 FORM-18 27-07-2012.pdf | 2012-07-27 |
| 7 | 5197-CHENP-2012 FORM-3 11-12-2012.pdf | 2012-12-11 |
| 8 | 5197-CHENP-2012 CORRESPONDENCE OTHERS 11-12-2012.pdf | 2012-12-11 |
| 9 | 5197-CHENP-2012 CORRESPONDENCE OTHERS 19-12-2012.pdf | 2012-12-19 |
| 10 | 5197-CHENP-2012 OTHER PATENT DOCUMENT 19-12-2012.pdf | 2012-12-19 |
| 11 | 5197-CHENP-2012 FORM-1 19-12-2012.pdf | 2012-12-19 |
| 12 | 5197-CHENP-2012 FORM-13 30-07-2013.pdf | 2013-07-30 |
| 13 | 8067.204-In; Form 13-Voluntary amendments; 30-July-2013.pdf | 2013-08-05 |
| 14 | 8067.204-IN, Amended claims-Marked version, 30-July-2013.pdf | 2013-08-05 |
| 15 | 5197-CHENP-2012 FORM-3 27-01-2014.pdf | 2014-01-27 |
| 16 | 5197-CHENP-2012 CORRESPONDENCE OTHERS 27-01-2014.pdf | 2014-01-27 |
| 17 | 5197-CHENP-2012 POWER OF ATTORNEY 27-01-2014.pdf | 2014-01-27 |
| 18 | 5197-CHENP-2012 FORM-3 15-12-2014.pdf | 2014-12-15 |
| 19 | 5197-CHENP-2012 CORRESPONDENCE OTHERS 15-12-2014.pdf | 2014-12-15 |
| 20 | 5197-CHENP-2012-Form 3-280915.pdf | 2016-03-28 |
| 21 | 5197-CHENP-2012-Correspondence-280915.pdf | 2016-03-28 |
| 22 | 5197-CHENP-2012-Power of Attorney-170316.pdf | 2016-07-11 |
| 23 | 5197-CHENP-2012-Form 3-170316.pdf | 2016-07-11 |
| 24 | 5197-CHENP-2012-Correspondence-F3-PA-170316.pdf | 2016-07-11 |
| 25 | Form 3 [08-11-2016(online)].pdf | 2016-11-08 |
| 26 | Form 26 [30-01-2017(online)].pdf | 2017-01-30 |
| 27 | Form 3 [24-03-2017(online)].pdf | 2017-03-24 |
| 28 | 5197-CHENP-2012-FER.pdf | 2017-03-24 |
| 29 | 5197-CHENP-2012-OTHERS [15-09-2017(online)].pdf | 2017-09-15 |
| 30 | 5197-CHENP-2012-FER_SER_REPLY [15-09-2017(online)].pdf | 2017-09-15 |
| 31 | 5197-CHENP-2012-CLAIMS [15-09-2017(online)].pdf | 2017-09-15 |
| 32 | 5197-CHENP-2012-Information under section 8(2) (MANDATORY) [15-03-2018(online)].pdf | 2018-03-15 |
| 33 | 5197-CHENP-2012-FORM 3 [15-03-2018(online)].pdf | 2018-03-15 |
| 34 | 5197-CHENP-2012-Information under section 8(2) (MANDATORY) [07-09-2018(online)].pdf | 2018-09-07 |
| 35 | 5197-CHENP-2012-FORM 3 [07-09-2018(online)].pdf | 2018-09-07 |
| 36 | 5197-CHENP-2012-HearingNoticeLetter.pdf | 2019-01-08 |
| 37 | 5197-CHENP-2012-Written submissions and relevant documents (MANDATORY) [20-02-2019(online)].pdf | 2019-02-20 |
| 38 | 5197-CHENP-2012-Annexure (Optional) [20-02-2019(online)].pdf | 2019-02-20 |
| 39 | Marked Up Claims_Granted 308218_27-02-2019.pdf | 2019-02-27 |
| 40 | Description_Granted 308218_27-02-2019.pdf | 2019-02-27 |
| 41 | Claims_Granted 308218_27-02-2019.pdf | 2019-02-27 |
| 42 | Abstract_Granted 308218_27-02-2019.pdf | 2019-02-27 |
| 43 | 5197-CHENP-2012-PatentCertificate27-02-2019.pdf | 2019-02-27 |
| 44 | 5197-CHENP-2012-IntimationOfGrant27-02-2019.pdf | 2019-02-27 |
| 45 | 5197-CHENP-2012-FORM-26 [20-01-2020(online)].pdf | 2020-01-20 |
| 46 | 5197-CHENP-2012-RELEVANT DOCUMENTS [18-03-2020(online)].pdf | 2020-03-18 |
Search Strategy
| 1 | 5197CHENP2012_22-03-2017.pdf |