Abstract: The purpose of the present invention is to provide a feed additive composition for ruminants the feed additive composition being highly protective in the lumens and exhibiting excellent dissolution in the gastrointestinal tract. The present invention pertains to a feed additive composition for ruminants containing (A) at least one selected from a hydrogenated vegetable oil and a hydrogenated animal oil which have a melting point higher than 50°C and lower than 90°C (B) lecithin (C) a biologically active substance (D) a natural vegetable oil and water the feed additive composition being characterized in that when a scattering profile is measured by a small angle/wide angle X-ray scattering method after holding the composition at 40°C for 15 minutes and then is measured again after further holding the composition at 40°C for 30 minutes the ratio (t/s) of the peak intensity (t) when the composition is held at 40°C for 45 minutes to the peak intensity (s) when the composition is held at 40°C for 15 minutes is 0.9-1.1 for a peak having a maximum peak intensity in a region in which the scattering angle 2? is 5° or less and the ratio (y/x) of the peak intensity (y) when the composition is held at 40°C for 45 minutes to the peak intensity (x) when the composition is held at 40°C for 15 minutes is 0.7-0.9 for a peak having a maximum peak intensity in a region in which the scattering angle 2? is 17-23°.
1. A feed additive composition for ruminants comprising (A) at least one selected from hydrogenated vegetable oil and 5 hydrogenated animal oil each having a melting point of higher than 50°C and lower than 90°C, (B) lecithin, (C) a biologically active substance, (D) a natural vegetable oil, and water, wherein when a scattering profile is measured after maintaining 10 at 4 0°C for 15 min , and then measured by further maintaining at 40°C for 30 min by a small-angle and wide-angle x-ray scattering method, a peak having the maximum peak intensity in a region where the scattering angle 29 is not more than 5° has a ratio 15 (t/s) of 0.9 - 1.1 wherein s is peak intensity when maintained at 40°C for 15 min and t is peak intensity when maintained at 40°C for 45 min, and a peak having the maximum peak intensity in a region where the scattering angle 29 is 17° - 23° has a ratio (y/x) of 20 0.7-0.9 wherein x is peak intensity when maintained at 40°C for 15 min and y is peak intensity when maintained at 40°C for 4 5 min.
2. The composition according to claim 1, wherein said natural 25 vegetable oil is at least one selected from the group consisting of soybean oil, palm oil, rape seed oil, canola oil, olive oil, almond oil, avocado oil and safflower oil.
3. The composition according to claim 1 or 2, wherein said 30 natural vegetable oil comprises a unsaturated fatty acid having a carbon atom number of 18 in 60 wt% to 95 wt% relative to the constituent fatty acid of the natural vegetable oil.
4. The composition according to any one of claims 1 to 3, 35 wherein said natural vegetable oil comprises oleic acid in 55 34 wt% to 90 wt% relative to the constituent fatty acid of the natural vegetable oil.
5. The composition according to any one of claims 1 to 4, 5 wherein said natural vegetable oil is olive oil.
6. The composition according to any one of claims 1 to 5, wherein said biologically active substance is at least one selected from the group consisting of amino acid, vitamin and a 10 vitamin-like substance.
7. The composition according to any one of claims 1 to 6, having, as a surface layer, a layer substantially free of a biologically active substance. 25
8. The composition according to claim 7, wherein the layer substantially free of a biologically active substance has a thickness of 30 urn to 110 urn. 35
WE CLAIM:
1. A feed additive composition for ruminants comprising
(A) at least one selected from hydrogenated vegetable oil and 5 hydrogenated animal oil each having a melting point of higher than 50°C and lower than 90°C, (B) lecithin, (C) a biologically active substance, (D) a natural vegetable oil, and water, wherein
when a scattering profile is measured after maintaining 10 at 4 0°C for 15 min , and then measured by further maintaining at 40°C for 30 min by a small-angle and wide-angle x-ray scattering method,
a peak having the maximum peak intensity in a region where the scattering angle 29 is not more than 5° has a ratio 15 (t/s) of 0.9 - 1.1 wherein s is peak intensity when maintained at 40°C for 15 min and t is peak intensity when maintained at 40°C for 45 min, and
a peak having the maximum peak intensity in a region where the scattering angle 29 is 17° - 23° has a ratio (y/x) of 20 0.7-0.9 wherein x is peak intensity when maintained at 40°C for 15 min and y is peak intensity when maintained at 40°C for 4 5 min.
2. The composition according to claim 1, wherein said natural
25 vegetable oil is at least one selected from the group
consisting of soybean oil, palm oil, rape seed oil, canola oil, olive oil, almond oil, avocado oil and safflower oil.
3. The composition according to claim 1 or 2, wherein said
30 natural vegetable oil comprises a unsaturated fatty acid having a carbon atom number of 18 in 60 wt% to 95 wt% relative to the constituent fatty acid of the natural vegetable oil.
4. The composition according to any one of claims 1 to 3,
35 wherein said natural vegetable oil comprises oleic acid in 55
34
wt% to 90 wt% relative to the constituent fatty acid of the natural vegetable oil.
5. The composition according to any one of claims 1 to 4,
5 wherein said natural vegetable oil is olive oil.
6. The composition according to any one of claims 1 to 5,
wherein said biologically active substance is at least one
selected from the group consisting of amino acid, vitamin and a
10 vitamin-like substance.
7. The composition according to any one of claims 1 to 6,
having, as a surface layer, a layer substantially free of a
biologically active substance.
25
8. The composition according to claim 7, wherein the layer
substantially free of a biologically active substance has a
thickness of 30 urn to 110 urn.
35
| # | Name | Date |
|---|---|---|
| 1 | 201947020018.pdf | 2019-05-21 |
| 2 | 201947020018-TRANSLATIOIN OF PRIOIRTY DOCUMENTS ETC. [21-05-2019(online)].pdf | 2019-05-21 |
| 3 | 201947020018-STATEMENT OF UNDERTAKING (FORM 3) [21-05-2019(online)].pdf | 2019-05-21 |
| 4 | 201947020018-PROOF OF RIGHT [21-05-2019(online)].pdf | 2019-05-21 |
| 5 | 201947020018-PRIORITY DOCUMENTS [21-05-2019(online)].pdf | 2019-05-21 |
| 6 | 201947020018-POWER OF AUTHORITY [21-05-2019(online)].pdf | 2019-05-21 |
| 7 | 201947020018-FORM 1 [21-05-2019(online)].pdf | 2019-05-21 |
| 8 | 201947020018-DRAWINGS [21-05-2019(online)].pdf | 2019-05-21 |
| 9 | 201947020018-DECLARATION OF INVENTORSHIP (FORM 5) [21-05-2019(online)].pdf | 2019-05-21 |
| 10 | 201947020018-COMPLETE SPECIFICATION [21-05-2019(online)].pdf | 2019-05-21 |
| 11 | 201947020018-CLAIMS UNDER RULE 1 (PROVISIO) OF RULE 20 [21-05-2019(online)].pdf | 2019-05-21 |
| 12 | Correspondence by Agent_Form1_03-06-2019.pdf | 2019-06-03 |
| 13 | 201947020018-FORM 3 [09-11-2019(online)].pdf | 2019-11-09 |
| 14 | 201947020018-FORM 18 [18-09-2020(online)].pdf | 2020-09-18 |
| 15 | 201947020018-FER.pdf | 2021-10-18 |
| 16 | 201947020018-FORM 3 [26-11-2021(online)].pdf | 2021-11-26 |
| 17 | 201947020018-FER_SER_REPLY [26-11-2021(online)].pdf | 2021-11-26 |
| 18 | 201947020018-CLAIMS [26-11-2021(online)].pdf | 2021-11-26 |
| 19 | 201947020018-US(14)-HearingNotice-(HearingDate-27-01-2022).pdf | 2021-12-16 |
| 20 | 201947020018-Correspondence to notify the Controller [24-01-2022(online)].pdf | 2022-01-24 |
| 21 | 201947020018-Written submissions and relevant documents [10-02-2022(online)].pdf | 2022-02-10 |
| 22 | 201947020018-Retyped Pages under Rule 14(1) [10-02-2022(online)].pdf | 2022-02-10 |
| 23 | 201947020018-FORM 3 [10-02-2022(online)].pdf | 2022-02-10 |
| 24 | 201947020018-2. Marked Copy under Rule 14(2) [10-02-2022(online)].pdf | 2022-02-10 |
| 25 | 201947020018-PatentCertificate11-02-2022.pdf | 2022-02-11 |
| 26 | 201947020018-IntimationOfGrant11-02-2022.pdf | 2022-02-11 |
| 27 | 201947020018-RELEVANT DOCUMENTS [11-09-2023(online)].pdf | 2023-09-11 |
| 1 | TPOE_25-05-2021.pdf |