Glucose Sensitive Insulin Derivatives

Abstract: The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention also relates to novel intermediates. Finally, the invention provides a pharmaceutical composition comprising the insulin derivatives of the invention and the use of such a composition in the treatment or prevention of medical conditions relating to diabetes.

Patent Information

Application #

Filing Date

19 October 2021

Publication Number

44/2021

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

nncp-in@novonordisk.com

Parent Application

Applicants

NOVO NORDISK A/S

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Inventors

1. HOEG-JENSEN, Thomas

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2. BEHRENS, Carsten

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3. CLÓ, Emiliano

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4. MÜNZEL, Martin, Werner, Borchsenius

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5. SAUERBERG, Per

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6. KRUSE, Thomas

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7. SPETZLER, Jane

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8. SENSFUSS, Ulrich

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9. HJØRRINGGAARD, Claudia, Ulrich

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