“Improved Process For The Production Of Nucleotide Sugars”

Abstract: The current invention provides methods (e.g., large-scale processes) for the production of nucleotide sugars, which are modified with a polymeric modifying group, such as poly(alkylene oxide) moieties (e.g., poly(ethylene glycol) or poly(propylene glycol)) moieties. A typical process of the invention includes anion exchange chromatography followed by an ultrafiltration procedure, such as tangential flow filtration. The process of the invention provides modified nucleotide sugars in unexpectedly high purity and high overall yields.

Patent Information

Application #

Filing Date

08 December 2009

Publication Number

34/2011

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Patent Number

Legal Status

Grant Date

2016-02-24

Renewal Date

Applicants

NOVO NORDISK A/S.

Novo Allé 2880 Bagsvaerd Denmark.

Inventors

1. DEFREES Shawn

126 Filly Drive North Wales PA 19454 U.S.A.

2. BOWE Caryn

310 Maple Avenue Doylestown PA 18901 U.S.A.

Specification

PLEASE SEE THE SPECIFICATION ATTACHED.

Documents

Application Documents

#	Name	Date
1	8002-DELNP-2009-Correspondence-Others-(14-12-2009).pdf	2009-12-14
2	8002-DELNP-2009-Assignment-(14-12-2009).pdf	2009-12-14
3	8002-DELNP-2009-Form-26-(25-03-2010).pdf	2010-03-25
4	8002-DELNP-2009-Form-1-(25-03-2010).pdf	2010-03-25
5	8002-DELNP-2009-Correspondence-Others-(25-03-2010).pdf	2010-03-25
6	8002-DELNP-2009-Form-3-(06-05-2010).pdf	2010-05-06
7	8002-DELNP-2009-Correspondence-Others-(06-05-2010).pdf	2010-05-06
8	8002-DELNP-2009-Form-18-(22-06-2010).pdf	2010-06-22
9	8002-DELNP-2009-Correspondence-Others-(22-06-2010).pdf	2010-06-22
10	Form-5.pdf	2011-08-20
11	Form-3.pdf	2011-08-20
13	Drawings.pdf	2011-08-20
14	8002-delnp-2009-Correspondence Others-(23-11-2012).pdf	2012-11-23
15	8002-delnp-2009-Correspondence Others-(28-03-2013).pdf	2013-03-28
16	8002-delnp-2009-Correspondence Others-(18-04-2013).pdf	2013-04-18
17	8002-delnp-2009-Correspondence Others-(13-11-2013).pdf	2013-11-13
18	8002-delnp-2009-Form-3-(18-07-2014).pdf	2014-07-18
19	8002-delnp-2009-Correspondence Others-(18-07-2014).pdf	2014-07-18
20	8002-delnp-2009-Correspondence Others-(12-09-2014).pdf	2014-09-12
21	8002-delnp-2009-Correspondence Others-(05-12-2014).pdf	2014-12-05
22	8002-delnp-2009--PCT-(05-12-2014).pdf	2014-12-05
23	8002-delnp-2009--Correspondence Others-(05-12-2014).pdf	2014-12-05
24	8002-delnp-2009-Others-(29-04-2015).pdf	2015-04-29
25	8002-delnp-2009-marked claims-(29-04-2015).pdf	2015-04-29
26	8002-delnp-2009-Epo Communication under-(29-04-2015).pdf	2015-04-29
27	8002-delnp-2009-Drawings-(29-04-2015).pdf	2015-04-29
28	8002-delnp-2009-Description (Complete)-(29-04-2015).pdf	2015-04-29
29	8002-delnp-2009-Correspondence Others-(29-04-2015).pdf	2015-04-29
30	8002-delnp-2009-Claims-(29-04-2015).pdf	2015-04-29
31	Retyped spec.pdf	2015-05-05
32	Response.pdf	2015-05-05
33	Relevant docs.pdf	2015-05-05
34	EPO Communication.pdf	2015-05-05
35	Amended claims.pdf	2015-05-05
36	Power of Attorney [07-09-2015(online)].pdf	2015-09-07
37	Form 6 [07-09-2015(online)].pdf	2015-09-07
38	Assignment [07-09-2015(online)].pdf	2015-09-07
39	8002-delnp-2009-GPA-(09-09-2015).pdf	2015-09-09
40	8002-delnp-2009-Form-2-(09-09-2015).pdf	2015-09-09
41	8002-delnp-2009-Form-1-(09-09-2015).pdf	2015-09-09
42	8002-delnp-2009-Correspondence Others-(09-09-2015).pdf	2015-09-09
43	8002-delnp-2009-Copy Form-6-(09-09-2015).pdf	2015-09-09
44	8002-delnp-2009-Assignment-(09-09-2015).pdf	2015-09-09
45	8002-DELNP-2009_EXAMREPORT.pdf	2016-06-30
46	Form 27 [28-02-2017(online)].pdf	2017-02-28
47	271543-8002-DELNP-2009.pdf	2018-11-30