Improved Procoagulant Antibodies

Abstract: The present invention relates to multispecific procoagulant antibodies capable of binding to coagulation Factor IX (FIX) and/or the activated form thereof Factor IXa (FIXa), and Factor X (FX) and/or the activated form thereof Factor Xa (FXa) and promoting FX activation by FIXa, antibodies binding their epitopes or parts thereof and methods and composition for treating subjects suffering from a coagulopathy such as haemophilia A as well as kits, methods of manufacture and methods of use.

Patent Information

Application #

Filing Date

10 February 2021

Publication Number

08/2021

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

nncp-in@novonordisk.com

Parent Application

Applicants

NOVO NORDISK A/S

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Inventors

1. THORN, Karina

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2. HANSEN, Bjarne, Gram

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3. JOHNSEN, Laust ,Bruun

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4. HARNDAHL, Mikkel, Nors

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5. YANG, Zhiru

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road Beijing, Changping District 102206

6. ØSTERGAARD, Henrik

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7. GREISEN, Per, J

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8. JOHANSSON, Eva

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9. RASCH, Morten, Grønbech

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10. CHEN, Jianhe

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road Beijing, Changping District 102206

11. SVENSSON, Anders

Novo Allé 2880 Bagsværd

12. ZHU, Haisun

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road Beijing, Changping District 102206

13. ZHOU, Rong

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road Beijing, Changping District 102206

Specification

Documents

Application Documents

#	Name	Date
1	202147005688-STATEMENT OF UNDERTAKING (FORM 3) [10-02-2021(online)].pdf	2021-02-10
2	202147005688-SEQUENCE LISTING(PDF) [10-02-2021(online)].pdf	2021-02-10
3	202147005688-SEQUENCE LISTING [10-02-2021(online)].txt	2021-02-10
4	202147005688-PRIORITY DOCUMENTS [10-02-2021(online)].pdf	2021-02-10
5	202147005688-POWER OF AUTHORITY [10-02-2021(online)].pdf	2021-02-10
6	202147005688-FORM 1 [10-02-2021(online)].pdf	2021-02-10
7	202147005688-DRAWINGS [10-02-2021(online)].pdf	2021-02-10
8	202147005688-DECLARATION OF INVENTORSHIP (FORM 5) [10-02-2021(online)].pdf	2021-02-10
9	202147005688-COMPLETE SPECIFICATION [10-02-2021(online)].pdf	2021-02-10
10	202147005688-FORM 18 [11-02-2021(online)].pdf	2021-02-11
11	202147005688-Proof of Right [20-05-2021(online)].pdf	2021-05-20
12	202147005688-FORM 3 [03-08-2021(online)].pdf	2021-08-03
13	202147005688.pdf	2021-10-18
14	202147005688-FORM 3 [02-02-2022(online)].pdf	2022-02-02
15	202147005688-FORM 3 [28-07-2022(online)].pdf	2022-07-28
16	202147005688-RELEVANT DOCUMENTS [15-12-2022(online)].pdf	2022-12-15
17	202147005688-POA [15-12-2022(online)].pdf	2022-12-15
18	202147005688-FORM 13 [15-12-2022(online)].pdf	2022-12-15
19	202147005688-FORM 3 [25-01-2023(online)].pdf	2023-01-25
20	202147005688-FORM 3 [20-07-2023(online)].pdf	2023-07-20
21	202147005688-FORM-26 [20-10-2023(online)].pdf	2023-10-20
22	202147005688-FORM 3 [19-01-2024(online)].pdf	2024-01-19
23	202147005688-FORM-26 [22-03-2024(online)].pdf	2024-03-22
24	202147005688-FER.pdf	2025-09-15
25	202147005688-FORM 3 [24-11-2025(online)].pdf	2025-11-24

Search Strategy

1	202147005688_SearchStrategyNew_E_searchstrategyAbE_11-09-2025.pdf