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Method For Enzymatic Sulfurylation Of Alcohols And Amines Using Bacterium Of The Family Enterobacteriaceae

Abstract: A method for enzymatic sulfurylation of a substrate is provided which includes the steps of reacting the substrate with 3"-phosphoadenosine-5"-phosphosulfate (PAPS) in a medium containing a bacterium belonging to the family Enterobacteriaceae to produce a sulfated derivative of the substrate, and collecting the sulfated derivative from the medium, wherein the bacterium has been modified to produce, at least, a protein having sulfotransferase activity, and to attenuate expression of an aphA gene, a cysQ gene, or a cpdB gene, or a combination of these.

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Patent Information

Application #
Filing Date
04 January 2021
Publication Number
03/2021
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
patent@depenning.com
Parent Application

Applicants

AJINOMOTO CO., INC.
15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315

Inventors

1. SMIRNOV, Sergey Vasilievich
c/o Closed Joint-Stock Company, Ajinomoto-Genetika Research Institute 1st Dorozhny pr., 1-1, Moscow 117545
2. TOKMAKOVA, Irina Lvovna
c/o Closed Joint-Stock Company, Ajinomoto-Genetika Research Institute 1st Dorozhny pr., 1-1, Moscow 117545

Specification

Documents

Application Documents

# Name Date
1 202147000162-FORM 18 [21-06-2022(online)].pdf 2022-06-21
2 202147000162-Correspondence_Form1, Power of Attorney_11-02-2022.pdf 2022-02-11
3 202147000162.pdf 2021-10-18
4 202147000162-FORM 3 [12-02-2021(online)].pdf 2021-02-12
5 202147000162-FORM-26 [25-01-2021(online)].pdf 2021-01-25
6 202147000162-COMPLETE SPECIFICATION [04-01-2021(online)].pdf 2021-01-04
7 202147000162-DECLARATION OF INVENTORSHIP (FORM 5) [04-01-2021(online)].pdf 2021-01-04
8 202147000162-DRAWINGS [04-01-2021(online)].pdf 2021-01-04
9 202147000162-FORM 1 [04-01-2021(online)].pdf 2021-01-04
10 202147000162-PRIORITY DOCUMENTS [04-01-2021(online)].pdf 2021-01-04
11 202147000162-PROOF OF RIGHT [04-01-2021(online)].pdf 2021-01-04
12 202147000162-SEQUENCE LISTING [04-01-2021(online)].txt 2021-01-04
13 202147000162-SEQUENCE LISTING(PDF) [04-01-2021(online)].pdf 2021-01-04
14 202147000162-STATEMENT OF UNDERTAKING (FORM 3) [04-01-2021(online)].pdf 2021-01-04