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Method For Preparing Polymeric Protein Composed Of Monomeric Protein Produced By Fusing Protein Having Immunoglobulin Fold Structure To Protein Capable Of Serving As Subunit Structure
Abstract: A method for preparing a polymeric protein which is composed of a monomeric protein produced by fusing a protein having an immunoglobulin fold structure to a protein that can serve as a subunit structure said method comprising: (A) a step of preparing the monomeric protein that has the form of granules insoluble in cells of a microorganism; (B) a step of solubilizing the monomeric protein prepared in step (A) in an aqueous solution containing lauroyl L Glu; (C) a step of diluting the solution prepared in step (B) with a buffer solution containing arginine hydrochloride to decrease the concentration of lauroyl L Glu; and (D) a step of replacing a solvent in the solution prepared in step (C) by a buffer solution by means of gel permeation chromatography or the like.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
20 January 2014
Publication Number
14/2015
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
patent@depenning.com
Parent Application
Patent Number
Legal Status
Grant Date
2019-08-23
Renewal Date
Applicants
AJINOMOTO CO. INC.
15 1 Kyobashi 1 chome Chuo ku Tokyo
1048315
Inventors
1. EJIMA Daisuke
c/o AJINOMOTO CO. INC. 1 1 Suzuki cho Kawasaki ku Kawasaki shi Kanagawa
2108681
2. SATO Haruna
c/o AJINOMOTO CO. INC. 1 1 Suzuki cho Kawasaki ku Kawasaki shi Kanagawa
2108681
3. TSUMOTO Kouhei
c/o The Institute of Medical Science The University of Tokyo 4 6 1 Shirokanedai Minato ku Tokyo
1088639
4. DATE Masayo
c/o AJINOMOTO CO. INC. 1 1 Suzuki cho Kawasaki ku Kawasaki shi Kanagawa
2108681
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | GPA.pdf | 2014-02-05 |
| 2 | F5.pdf | 2014-02-05 |
| 3 | F3.pdf | 2014-02-05 |
| 4 | 436-CHENP-2014.pdf | 2014-02-05 |
| 5 | 178-2014-COMPLETE SPECIFICATION.pdf | 2014-02-05 |
| 6 | 436-CHENP-2014 FORM-1 09-07-2014.pdf | 2014-07-09 |
| 7 | 436-CHENP-2014 CORRESPONDENCE OTHERS 09-07-2014.pdf | 2014-07-09 |
| 8 | 436-CHENP-2014 FORM-3 14-07-2014.pdf | 2014-07-14 |
| 9 | 436-CHENP-2014 CORRESPONDENCE OTHERS 14-07-2014.pdf | 2014-07-14 |
| 10 | ENGLISH TRANSLATION.pdf | 2014-10-23 |
| 11 | 436-CHENP-2014 FORM-3 01-04-2015.pdf | 2015-04-01 |
| 12 | 436-CHENP-2014 CORRESPONDENCE OTHERS 01-04-2015.pdf | 2015-04-01 |
| 13 | 436-CHENP-2014 FORM-3 20-08-2015.pdf | 2015-08-20 |
| 14 | 436-CHENP-2014 CORRESPONDENCE OTHERS 20-08-2015.pdf | 2015-08-20 |
| 15 | 436-CHENP-2014-FORM3-190216.pdf | 2016-06-30 |
| 16 | 436-CHENP-2014-CORRESPONDENCE-F3-190216.pdf | 2016-06-30 |
| 17 | Form 3 [09-09-2016(online)].pdf | 2016-09-09 |
| 18 | Form 3 [08-06-2017(online)].pdf | 2017-06-08 |
| 19 | 436-CHENP-2014-FORM 3 [12-01-2018(online)].pdf | 2018-01-12 |
| 20 | 436-CHENP-2014-FORM 3 [13-07-2018(online)].pdf | 2018-07-13 |
| 21 | 436-CHENP-2014-FER.pdf | 2018-07-27 |
| 22 | 436-CHENP-2014-OTHERS [21-01-2019(online)].pdf | 2019-01-21 |
| 23 | 436-CHENP-2014-Information under section 8(2) (MANDATORY) [21-01-2019(online)].pdf | 2019-01-21 |
| 24 | 436-CHENP-2014-FORM 3 [21-01-2019(online)].pdf | 2019-01-21 |
| 25 | 436-CHENP-2014-FER_SER_REPLY [21-01-2019(online)].pdf | 2019-01-21 |
| 26 | 436-CHENP-2014-COMPLETE SPECIFICATION [21-01-2019(online)].pdf | 2019-01-21 |
| 27 | 436-CHENP-2014-CLAIMS [21-01-2019(online)].pdf | 2019-01-21 |
| 28 | 436-CHENP-2014-certified copy of translation (MANDATORY) [21-01-2019(online)].pdf | 2019-01-21 |
| 29 | 436-CHENP-2014-ABSTRACT [21-01-2019(online)].pdf | 2019-01-21 |
| 30 | 436-CHENP-2014-Information under section 8(2) (MANDATORY) [14-08-2019(online)].pdf | 2019-08-14 |
| 31 | 436-CHENP-2014-FORM 3 [14-08-2019(online)].pdf | 2019-08-14 |
| 32 | Marked up Claims_Granted 318851_23-08-2019.pdf | 2019-08-23 |
| 33 | Drawings_Granted 318851_23-08-2019.pdf | 2019-08-23 |
| 34 | Description_Granted 318851_23-08-2019.pdf | 2019-08-23 |
| 35 | Claims_Granted 318851_23-08-2019.pdf | 2019-08-23 |
| 36 | Abstract_Granted 318851_23-08-2019.pdf | 2019-08-23 |
| 37 | 436-CHENP-2014-PatentCertificate23-08-2019.pdf | 2019-08-23 |
| 38 | 436-CHENP-2014-IntimationOfGrant23-08-2019.pdf | 2019-08-23 |
| 39 | 436-CHENP-2014-RELEVANT DOCUMENTS [21-02-2020(online)].pdf | 2020-02-21 |
| 40 | 436-CHENP-2014-RELEVANT DOCUMENTS [27-07-2021(online)].pdf | 2021-07-27 |
| 41 | 436-CHENP-2014-RELEVANT DOCUMENTS [23-09-2022(online)].pdf | 2022-09-23 |
| 42 | 436-CHENP-2014-RELEVANT DOCUMENTS [11-09-2023(online)].pdf | 2023-09-11 |
Search Strategy
| 1 | multimericprotein_24-07-2018.pdf |