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Method For Secretory Production Of Unnatural Amino Acid Containing Protein

Abstract: Provided is a method for the secretory production of an unnatural-amino-acid-containing protein. In the present invention, coryneform bacteria that have a genetic construct for secretory expression of an unnatural-amino-acid-containing protein and that have been modified to express an orthogonal pair of tRNA and aminoacyl-tRNA synthetase corresponding to the unnatural-amino acid are cultured, and an unnatural-amino-acid-containing protein is produced by secretion.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
05 February 2024
Publication Number
10/2024
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
Parent Application

Applicants

AJINOMOTO CO., INC.
15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315

Inventors

1. HARUNA, Kenichi
c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
2. SATO, Haruna
c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
3. MATSUDA, Yoshihiko
c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681
4. ITO, Kenichiro
c/o AJINOMOTO CO., INC., 1-1, Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Kanagawa 2108681

Specification

Documents

Application Documents

# Name Date
1 202447007593-STATEMENT OF UNDERTAKING (FORM 3) [05-02-2024(online)].pdf 2024-02-05
3 202447007593-Sequence Listing in PDF [05-02-2024(online)].pdf 2024-02-05
4 202447007593-PROOF OF RIGHT [05-02-2024(online)].pdf 2024-02-05
5 202447007593-PRIORITY DOCUMENTS [05-02-2024(online)].pdf 2024-02-05
6 202447007593-FORM 1 [05-02-2024(online)].pdf 2024-02-05
7 202447007593-DRAWINGS [05-02-2024(online)].pdf 2024-02-05
8 202447007593-DECLARATION OF INVENTORSHIP (FORM 5) [05-02-2024(online)].pdf 2024-02-05
9 202447007593-COMPLETE SPECIFICATION [05-02-2024(online)].pdf 2024-02-05
10 202447007593-FORM-26 [19-03-2024(online)].pdf 2024-03-19
11 202447007593-FORM 3 [18-07-2024(online)].pdf 2024-07-18
12 202447007593-RELEVANT DOCUMENTS [19-06-2025(online)].pdf 2025-06-19
13 202447007593-MARKED COPIES OF AMENDEMENTS [19-06-2025(online)].pdf 2025-06-19
14 202447007593-FORM 18 [19-06-2025(online)].pdf 2025-06-19
15 202447007593-FORM 13 [19-06-2025(online)].pdf 2025-06-19
16 202447007593-AMMENDED DOCUMENTS [19-06-2025(online)].pdf 2025-06-19