Mic 1 Compounds And Uses Thereof

Abstract: The invention relates to MIC-1 compounds. More specifically it relates to compounds comprising a MIC-1 polypeptide with an N-terminal amino acid extension and a protractor wherein the amino acid extension comprises 3 to 36 amino acid residues and where the MIC-1 polypeptide and the N-terminal amino acid extension together have a calculated pI lower than 6.5. The compounds of the invention have MIC-1 activity. The invention also relates to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable excipients, as well as the medical use of the compounds.

Patent Information

Application #

Filing Date

02 December 2019

Publication Number

50/2019

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

nncp-in@novonordisk.com

Parent Application

Applicants

NOVO NORDISK A/S

Novo Allé, 2880 Bagsværd

Inventors

1. GAO, Xiang

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road, Beijing, Changping District 102206

2. ZHANG, Xujia

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road, Beijing, Changping District 102206

3. GUAN, Hongtao

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road, Beijing, Changping District 102206

4. THØGERSEN, Henning

Novo Allé, 2880 Bagsværd

5. SASS-ØRUM, Kristian

Novo Allé, 2880 Bagsværd

6. IVERSEN, Lars, Fogh

Novo Allé, 2880 Bagsværd

7. NØRGAARD, Per

Novo Allé, 2880 Bagsværd

8. JØRGENSEN, Sebastian, Beck

Novo Allé, 2880 Bagsværd

9. HANSEN, Kristian, Tage

Novo Allé, 2880 Bagsværd

10. WANG, Yi

Beijing Novo Nordisk Pharmaceuticals Sci & Tech Co. Ltd Building #2/#4, Bio-tech R&D Center, No.20 Life Science Park Road, Beijing, Changping District 102206

11. FRIEBOES, Kilian, Waldemar, Conde

Novo Allé, 2880 Bagsværd

12. WIECZOREK, Birgit

Novo Allé, 2880 Bagsværd

Specification

Soft Copy Attached in PDF

Documents

Application Documents

#	Name	Date
1	201947049426.pdf	2019-12-02
2	201947049426-STATEMENT OF UNDERTAKING (FORM 3) [02-12-2019(online)].pdf	2019-12-02
3	201947049426-SEQUENCE LISTING(PDF) [02-12-2019(online)].pdf	2019-12-02
4	201947049426-SEQUENCE LISTING [02-12-2019(online)].txt	2019-12-02
5	201947049426-PRIORITY DOCUMENTS [02-12-2019(online)].pdf	2019-12-02
6	201947049426-POWER OF AUTHORITY [02-12-2019(online)].pdf	2019-12-02
7	201947049426-FORM 18 [02-12-2019(online)].pdf	2019-12-02
8	201947049426-FORM 1 [02-12-2019(online)].pdf	2019-12-02
9	201947049426-DRAWINGS [02-12-2019(online)].pdf	2019-12-02
10	201947049426-DECLARATION OF INVENTORSHIP (FORM 5) [02-12-2019(online)].pdf	2019-12-02
11	201947049426-COMPLETE SPECIFICATION [02-12-2019(online)].pdf	2019-12-02
12	Correspondence by Agent_Sequence Listing_05-12-2019.pdf	2019-12-05
13	201947049426-Proof of Right [01-06-2020(online)].pdf	2020-06-01
14	201947049426-FORM 3 [01-06-2020(online)].pdf	2020-06-01
15	201947049426-FORM 3 [27-11-2020(online)].pdf	2020-11-27
16	201947049426-FORM 3 [27-05-2021(online)].pdf	2021-05-27
17	201947049426-FORM 3 [16-11-2021(online)].pdf	2021-11-16
18	201947049426-FORM 3 [10-05-2022(online)].pdf	2022-05-10
19	201947049426-FER.pdf	2022-08-02
20	201947049426-Information under section 8(2) [28-10-2022(online)].pdf	2022-10-28
21	201947049426-FORM 3 [28-10-2022(online)].pdf	2022-10-28
22	201947049426-RELEVANT DOCUMENTS [30-11-2022(online)].pdf	2022-11-30

Search Strategy

1	strategy_49246E_01-08-2022.pdf