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N Terminal Extension Sequences And Methods For Expression Of Recombinant Therapeutic Peptides
Abstract: The invention relates to an N-terminal extension sequences which are employed to enhance the expression of recombinant therapeutic peptides. The invention also relates to a process for the 5 high-level expression of recombinant therapeutic peptides using the said N-terminal extension sequence. The invention also provides nucleic acids, vectors and recombinant host cells for efficient production of biologically active proteins such as lirapeptide.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
13 September 2019
Publication Number
12/2021
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
hyderabad@knspartners.com
Parent Application
Applicants
BIOLOGICAL E LIMITED
18/1 & 3, Azamabad, Hyderabad, Telangana, India, Pin Code–500 020.
Inventors
1. RAMESH VENKAT MATUR
Biological E. Ltd., 18/1 & 3, Azamabad, Hyderabad, Telangana, India, Pin Code–500 020.
2. RAJAN SRIRAMAN
Biological E. Ltd., 18/1 & 3, Azamabad, Hyderabad, Telangana, India, Pin Code–500 020.
3. REGATTI PAVAN
Biological E. Ltd., 18/1 & 3, Azamabad, Hyderabad, Telangana, India, Pin Code–500 020.
4. MANTENA NARENDER DEV
Biological E. Ltd., 18/1 & 3, Azamabad, Hyderabad, Telangana, India, Pin Code–500 020.
5. MAHIMA DATLA
Biological E. Ltd., 18/1 & 3, Azamabad, Hyderabad, Telangana, India, Pin Code–500 020.
Specification
DESC:Please refer the attached Complete Specification ,CLAIMS:Please refer the attached Complete Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 201941009728-FORM 18 [06-09-2023(online)].pdf | 2023-09-06 |
| 1 | 201941009728-FORM 3 [27-03-2025(online)].pdf | 2025-03-27 |
| 1 | 201941009728-STATEMENT OF UNDERTAKING (FORM 3) [13-03-2019(online)].pdf | 2019-03-13 |
| 2 | 201941009728-Covering Letter [24-09-2020(online)].pdf | 2020-09-24 |
| 2 | 201941009728-FORM 18 [06-09-2023(online)].pdf | 2023-09-06 |
| 2 | 201941009728-SEQUENCE LISTING(PDF) [13-03-2019(online)].pdf | 2019-03-13 |
| 3 | 201941009728-Covering Letter [24-09-2020(online)].pdf | 2020-09-24 |
| 3 | 201941009728-Form 1 (Submitted on date of filing) [24-09-2020(online)].pdf | 2020-09-24 |
| 3 | 201941009728-SEQUENCE LISTING [13-03-2019(online)].txt | 2019-03-13 |
| 4 | 201941009728-PROVISIONAL SPECIFICATION [13-03-2019(online)].pdf | 2019-03-13 |
| 4 | 201941009728-Power of Attorney [24-09-2020(online)].pdf | 2020-09-24 |
| 4 | 201941009728-Form 1 (Submitted on date of filing) [24-09-2020(online)].pdf | 2020-09-24 |
| 5 | 201941009728-Power of Attorney [24-09-2020(online)].pdf | 2020-09-24 |
| 5 | 201941009728-FORM 3 [17-09-2020(online)].pdf | 2020-09-17 |
| 5 | 201941009728-FORM 1 [13-03-2019(online)].pdf | 2019-03-13 |
| 6 | 201941009728-FORM 3 [17-09-2020(online)].pdf | 2020-09-17 |
| 6 | 201941009728-FIGURE OF ABSTRACT [13-03-2019(online)].pdf | 2019-03-13 |
| 6 | 201941009728-COMPLETE SPECIFICATION [12-09-2020(online)].pdf | 2020-09-12 |
| 7 | 201941009728-DRAWINGS [13-03-2019(online)].pdf | 2019-03-13 |
| 7 | 201941009728-CORRESPONDENCE-OTHERS [12-09-2020(online)].pdf | 2020-09-12 |
| 7 | 201941009728-COMPLETE SPECIFICATION [12-09-2020(online)].pdf | 2020-09-12 |
| 8 | 201941009728-CORRESPONDENCE-OTHERS [12-09-2020(online)].pdf | 2020-09-12 |
| 8 | 201941009728-DECLARATION OF INVENTORSHIP (FORM 5) [13-03-2019(online)].pdf | 2019-03-13 |
| 8 | 201941009728-DRAWING [12-09-2020(online)].pdf | 2020-09-12 |
| 9 | 201941009728-DRAWING [12-09-2020(online)].pdf | 2020-09-12 |
| 9 | 201941009728-ENDORSEMENT BY INVENTORS [12-09-2020(online)].pdf | 2020-09-12 |
| 9 | 201941009728-FORM-26 [27-03-2019(online)].pdf | 2019-03-27 |
| 10 | 201941009728-ENDORSEMENT BY INVENTORS [12-09-2020(online)].pdf | 2020-09-12 |
| 10 | 201941009728-SEQUENCE LISTING (.txt) [12-09-2020(online)].txt | 2020-09-12 |
| 10 | Correspondence by Agent_Power of Attorney_01-04-2019.pdf | 2019-04-01 |
| 11 | 201941009728-APPLICATIONFORPOSTDATING [11-03-2020(online)].pdf | 2020-03-11 |
| 11 | 201941009728-Proof of Right (MANDATORY) [14-10-2019(online)].pdf | 2019-10-14 |
| 11 | 201941009728-SEQUENCE LISTING (.txt) [12-09-2020(online)].txt | 2020-09-12 |
| 12 | 201941009728-APPLICATIONFORPOSTDATING [11-03-2020(online)].pdf | 2020-03-11 |
| 12 | 201941009728-PostDating-(11-03-2020)-(E-6-53-2020-CHE).pdf | 2020-03-11 |
| 13 | 201941009728-Proof of Right (MANDATORY) [14-10-2019(online)].pdf | 2019-10-14 |
| 13 | 201941009728-PostDating-(11-03-2020)-(E-6-53-2020-CHE).pdf | 2020-03-11 |
| 13 | 201941009728-APPLICATIONFORPOSTDATING [11-03-2020(online)].pdf | 2020-03-11 |
| 14 | 201941009728-Proof of Right (MANDATORY) [14-10-2019(online)].pdf | 2019-10-14 |
| 14 | 201941009728-SEQUENCE LISTING (.txt) [12-09-2020(online)].txt | 2020-09-12 |
| 14 | Correspondence by Agent_Power of Attorney_01-04-2019.pdf | 2019-04-01 |
| 15 | 201941009728-ENDORSEMENT BY INVENTORS [12-09-2020(online)].pdf | 2020-09-12 |
| 15 | 201941009728-FORM-26 [27-03-2019(online)].pdf | 2019-03-27 |
| 15 | Correspondence by Agent_Power of Attorney_01-04-2019.pdf | 2019-04-01 |
| 16 | 201941009728-DECLARATION OF INVENTORSHIP (FORM 5) [13-03-2019(online)].pdf | 2019-03-13 |
| 16 | 201941009728-DRAWING [12-09-2020(online)].pdf | 2020-09-12 |
| 16 | 201941009728-FORM-26 [27-03-2019(online)].pdf | 2019-03-27 |
| 17 | 201941009728-DECLARATION OF INVENTORSHIP (FORM 5) [13-03-2019(online)].pdf | 2019-03-13 |
| 17 | 201941009728-DRAWINGS [13-03-2019(online)].pdf | 2019-03-13 |
| 17 | 201941009728-CORRESPONDENCE-OTHERS [12-09-2020(online)].pdf | 2020-09-12 |
| 18 | 201941009728-DRAWINGS [13-03-2019(online)].pdf | 2019-03-13 |
| 18 | 201941009728-FIGURE OF ABSTRACT [13-03-2019(online)].pdf | 2019-03-13 |
| 18 | 201941009728-COMPLETE SPECIFICATION [12-09-2020(online)].pdf | 2020-09-12 |
| 19 | 201941009728-FIGURE OF ABSTRACT [13-03-2019(online)].pdf | 2019-03-13 |
| 19 | 201941009728-FORM 1 [13-03-2019(online)].pdf | 2019-03-13 |
| 19 | 201941009728-FORM 3 [17-09-2020(online)].pdf | 2020-09-17 |
| 20 | 201941009728-FORM 1 [13-03-2019(online)].pdf | 2019-03-13 |
| 20 | 201941009728-Power of Attorney [24-09-2020(online)].pdf | 2020-09-24 |
| 20 | 201941009728-PROVISIONAL SPECIFICATION [13-03-2019(online)].pdf | 2019-03-13 |
| 21 | 201941009728-Form 1 (Submitted on date of filing) [24-09-2020(online)].pdf | 2020-09-24 |
| 21 | 201941009728-PROVISIONAL SPECIFICATION [13-03-2019(online)].pdf | 2019-03-13 |
| 21 | 201941009728-SEQUENCE LISTING [13-03-2019(online)].txt | 2019-03-13 |
| 22 | 201941009728-Covering Letter [24-09-2020(online)].pdf | 2020-09-24 |
| 22 | 201941009728-SEQUENCE LISTING [13-03-2019(online)].txt | 2019-03-13 |
| 22 | 201941009728-SEQUENCE LISTING(PDF) [13-03-2019(online)].pdf | 2019-03-13 |
| 23 | 201941009728-FORM 18 [06-09-2023(online)].pdf | 2023-09-06 |
| 23 | 201941009728-SEQUENCE LISTING(PDF) [13-03-2019(online)].pdf | 2019-03-13 |
| 23 | 201941009728-STATEMENT OF UNDERTAKING (FORM 3) [13-03-2019(online)].pdf | 2019-03-13 |
| 24 | 201941009728-FORM 3 [27-03-2025(online)].pdf | 2025-03-27 |
| 24 | 201941009728-STATEMENT OF UNDERTAKING (FORM 3) [13-03-2019(online)].pdf | 2019-03-13 |