The present disclosure relates to multivalent pneumococcal vaccine compositions comprising capsular pneumococcal polysaccharide serotypes each individually conjugated to carrier proteins. When conjugated, the combination of the capsular pneumococcal polysaccharide serotype and the carrier protein is referred to here...
Abstract
The invention relates to a method for the removal of protein and other impurities from microbial capsular polysaccharides. More particularly, the present invention relates to isolation of microbial capsular polysaccharides in pure form after removal of protein and other impurities.
The present invention relates for the production of high level expression of recombinant toxin protein CRM 197, production in bacterial hosts. In particular, the present invention relates to recombinant microorganisms, are disclosed that have been engineered to express a CRM 197 alone or in combination with recombin...
Abstract of the Invention
The present invention relates to an improved process for production of Aluminium
phosphate (AlPhos) gel wherein the solutions of aluminium salt and alkaline phosphate salt
are added to water by maintaining the pH under stirring to obtain the precipitate, followed
by sterilization of the said ...
A new manufacturing process for preparing pure capsular polysachharide using aluminum phosphate with alcohol for the purification of capsular polysaccharides of Haemophilus influenza - b, Neisseria meningitis such as serotypes A,C,Y,W-135 and other similar related capsular polysaccharides produced form both gram neg...
The present invention relates to high level expression of bacterial toxoid or toxin protein of pharmacological interest by means of an optimized novel polynucleotide sequence and host transformed with the said polynucleotide. Specifically, the invention provides a method for high production of polypeptide CRM197 where...
The present invention relates to a soft-gelatin capsule formulation of antitussive agents. More particularly, the present invention relates to soft-gelatin capsule formulation comprising Noscapine or its pharmaceutically acceptable salts alone or in combination with one or more therapeutically active agents.
...
Abstract of the invention
The present invention relates to a multivalent Pneumococcal conjugate vaccine (PCV)
composition comprising: at least 12 capsular polysaccharides selected from serotypes 1, 3, 4, 5, 6B, 7F,
9N, 9V, 15B, 14, 18C, 19A, 19F, 22F, 23F and 33F of S. pneumoniae activated
with CDAP and con...
The present invention relates to expression of Pneumococcal Surface Protein A (PspA). The invention represents an advancement in the field of genetic engineering and vaccine technology. The invention discloses expression vectors and recombinant host cells for expression of truncated PspA peptide. The invention also ...
The present invention relates to multivalent pneumococcal polysaccharide-protein conjugates vaccine composition comprising pneumococcal capsular polysaccharide of one or more Streptococcus pneumoniae serotypes conjugated to one or more carrier proteins.
The present invention relates to multivalent pneumococcal polysaccharide-protein conjugates vaccine composition comprising pneumococcal capsular polysaccharide of one or more Streptococcus pneumoniae serotypes conjugated to one or more carrier proteins.
The present invention provides an improved process for the preparation of Dalteparin sodium. The process is simple, commercially viable and industrially advantageous.
PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT
HEPARIN The present invention provides an improved process for the preparation of Enoxaparin sodium. The process is simple, commercially viable and industrially advantageous.
An industrially scalable method for the preparation of carrier proteins selected
from tetanus toxoid (TT), diphtheria toxoid (DT), Cross Reactive Material 197
(CRM197), Haemophilus influenzae protein D, Neisseria outer membrane protein,
Pertussis toxin (PT), Pertactin (PRN) and filamentous hemagglutinin (FHA) and
the ...
The present invention provides an improved method for the production of CRM197 with high yield using engineered Corynebacterium diphtheria strain having increased copy number of CRM197 gene, wherein the method comprises growing the strain in a media free of animal derived components with one or more amino acids.
...
The present invention relates to vaccine formulations comprising preservative systems. More particularly, the present invention relates to preservative systems for vaccine formulations which is free of thiomersal, and comprising 2-phenoxyethanol and at least one other preservative selected from m-cresol, benzyl alco...
The invention relates to capsular polysaccharides of Streptococcus pneumoniae. More specifically, the present invention relates to sized and purified capsular polysaccharides of Streptococcus pneumoniae serotypes 2, 15A, 15C & 35B and process for their preparation.
The present invention provides an alcohol free purification process of capsular polysaccharides. The present invention is an improvement over the existing processes which are tedious and complex multi-step processes. The purification process of the present invention does not involve use of alcohol, chromatographic m...
The present invention relates to multivalent pneumococcal polysaccharide-protein conjugates vaccine composition comprising pneumococcal capsular polysaccharide of one or more Streptococcus pneumoniae serotypes conjugated to one or more carrier proteins.
The present invention provides inactivated poliomyelitis vaccine compositions comprising at least one inactivated poliovirus S19 strain for prevention of poliomyelitis. The present invention provides safe, stable and effective vaccine formulations which can be manufactured at low containment level leading to large s...
The present invention provides a method for purification of Streptococcus pneumoniae Type 3 capsular polysaccharide from fermentation broth comprising protein and complex impurities. The method provides for purification of capsular polysaccharide of Streptococcus pneumonia serotype 3 at a lower temperature range of ...
The present invention provides a colorimetric based method for quantifying carbohydrates in a given aqueous sample. The method provided by the invention uses 2-Phenoxyethanol as a novel reagent for quantifying carbohydrates in a given sample. The present invention is a rapid, sensitive, simple and direct method for ...
The invention relates to an N-terminal extension sequences which are employed to enhance the expression of recombinant therapeutic peptides. The invention also relates to a process for the 5 high-level expression of recombinant therapeutic peptides using the said N-terminal extension sequence. The invention also pro...
The present invention relates to an immunogenic composition comprising Vi capsular polysaccharide protein conjugate. More particularly, the present invention provides an immunogenic composition comprising fragmented Vi capsular polysaccharide having an average molecular weight between 100-200 KD conjugated to a carr...
The present invention pertains to a multivalent vaccine formulation comprising at least one inactivated poliovirus (IPV) S19 strain selected from S19 Type 1, S19 Type 2 and S19 Type 3 and at least one antigen selected from Diphtheria toxoid (DT), Tetanus toxoid (TT), whole-cell Bordetella pertussis (wP), acellular P...
The present invention relates to field of protein expression. It provides expression constructs and
methods for increased expression of recombinant proteins. More particularly, it provides
constructs and methods for enhanced expression of Lira-peptide in a recombinant host cell.
The present invention broadly relates to the improved method for purification of capsular polysaccharides. Particularly, the present invention relates to the method of purification of capsular polysaccharides from Streptococcus pneumoniae and other similar related capsular polysaccharides produced from both gram-neg...
The present disclosure relates to a process for preparing a stable floccule of paliperidone ester injectable suspension. The process comprises wet milling a premix slurry comprising paliperidone ester to obtain a milled suspension; and subjecting the milled suspension to heat treatment to produce a stable floccule o...
“EXPRESSION CASSETTES FOR PROTEIN EXPRESSION, METHOD(S) AND APPLICATION(S) THEREOF”
ABSTRACT
The present disclosure relates to expression cassettes that enhance protein secretion. The expression cassettes are composed of a specific combination of polynucleotides encoding expression enhancers and signal peptide...
The present disclosure relates to compositions and methods for stabilizing immunogenic
compositions. Particularly, the present disclosure provides an easy to prepare and economical
stabilizer composition comprising components selected from a group comprising sugar(s), amino
10 acid(s), protein(s) or peptide(s), m...
The present invention relates to a method for covalent coupling of polysaccharides to proteins for the preparation of Pneumococcal Conjugate Vaccines (monovalent) using low quantities/ratios of 1-Cyano 4-Dimethyl Amino Pyridinium tetrafluoroborate (CDAP) thereby preventing the destruction of immunogenic epitopes and...
[Class : 35] Services Of Marketing Distributors, Export, And Import Retailers Of Medicinal And Pharmaceuticals Products And Kits; Services Of Business Operations, Business Of Administration; Office Functions; Consultancies; Business Advisory Services; Managements; Advertising Services
[Class : 5] Pharmaceutical And Medicinal Preparations, Deodourisers For Hygenic Purposes, Disinfectants (Medicated), Medicated Paper Napkins, Medicated Tissues, Medicated Soaps And Lotions, Medicated Nappies, Massage Oil (Medicated) All Included In Class 5.
[Class : 32] Beers, Aerated And Non Aerated Beverages, Mineral Waters And Non Alcoholic Drinks, Syrups, Extracts And Essence For Making Nonalcoholic Beverages, Concentrates, Juices, Squashes.
[Class : 5] Medicinal And Pharmaceutical, Veterinary And Sanitary Substances; Diagnostic Preparations For Medicinal Purposes, Infants And Invalids Foods, Plasters, Material For Bandaging; Materials For Stopping Teeth, Dental Wax; Disinfectants; Preparation For Killing Weeds And Destroying Vermin.
[Class : 29] Meat, Fish, Poultry And Game, Meat Extracts Preserved, Dried Frozen And Cooked Fruits And Vegetables, Jellies, Jams Eggs, Milk And Other Dairy Products, Yogurts Edible Oils, Vanaspati, Ghee, Soya Bean Oils, And Fats, Preserves And Pickles All Kinds Of Soups Powders Soup Cubes, Soup Tablets Included In Class 29.
[Class : 19] Building Materials, Natural And Artificial Stone, Cement, And Portland Lime, Mortar Plastic And Gravel, Pipes Of Earthenware Or Cement, Road Making Materials, Asphalt Pitch And Bitumen, Portable Buildings, And Chimney Pots All Being Goods Included In Class 19.
[Class : 5] Pharmaceutical And Medicinal Preparations
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[Class : 16] Programmers, Magazines, Periodicals And Printed Matters, Catalogues, Software, Photographs, Stationery, Paper And Paper Articles, Instructional And Teaching Materials (Except Apparatus), Playing Cards, Printers Blocks And Printers Types, Book Binding Materials, Pen Stands, Adhesives For Household Purposes, Artists Materials, Plastic Materials For Packaging (Not ...
[Class : 4] Pharmaceutical Preparation In Gel Form.
["Trade mark is likely to be removed due to non filing of Renewal request within prescribed time limit In case of any discripancy contact respective TM Registry. "]
[Class : 35] Services Of Marketing Distributors, Export And Import Retailers Of Medicinal And Pharmaceuticals Products And Kits; Services Of Business Operations, Business Of Administration; Office Functions; Consultancies; Business Advisory Services; Managements; Advertising Services;
[Class : 5] Pharmaceutical And Medicinal Preparations.
["Trade mark is likely to be removed due to non filing of Renewal request within prescribed time limit In case of any discripancy contact respective TM Registry. "]
[Class : 5] Medicinal & Pharmaceutical,Veterinary & Sanitary Substances;Diagnostic Preparations For Medicinal Purposes,Infants And Invalids Foods,Plasters,Material For Bandaging,Materials For Stopping Teeth,Dental Wax;Disinfectants;Preparation For Killing Weeds And Destroying Vermin
["Trade mark is likely to be removed due to non filing of Renewal request within prescribed time limit In case of any discripancy contact respective TM Registry. "]
[Class : 16] All Type Of Printed Matter, Journals, New Paper And Preriodicals, Magazines Paper And Paper Articles, Cardborad And Cardboard Articles, Paper Tapes And Cards For Recordal Of Computer Programmes, Computer Aided Designs, Data Presentitions All Included In Class 16.
[Class : 5] Medicinal And Pharmaceutical Preparations.
["Trade mark is likely to be removed due to non filing of Renewal request within prescribed time limit In case of any discripancy contact respective TM Registry. "]
[Class : 5] Pharmaceutical And Medicinal Preparations Orally To Supply Maintenance, Electrolytes And Fluid And To Replace Mild To Moderate Losses When Food Intake Is Discontinued.
[Class : 3] Soaps, Toilet Preparations, Detergents, Cosmetics All Kinds Of Toileteries Dish Washing And Cleaning Preparations, Pre And After Shaving Lotions Room Deodourisers Other Than For Personal Use, Bath Salts, Bluing For Laundatory All Included In Class 3.
[Class : 5] Medicinal And Pharmaceutical, Veterinary And Sanitary Substances; Diagnostic Preparations For Medicinal Purposes, Infants And Invalids Foods, Plasters, Material For Bandaging; Materials For Stopping Teeth, Dental Wax; Disinfectants; Preparation For Killing Weeds And Destroying Vermin.
[Class : 5] Medicinal And Pharmaceutical Preparations .
["Trade mark is likely to be removed due to non filing of Renewal request within prescribed time limit In case of any discripancy contact respective TM Registry. "]
[Class : 5] Pharmaceutical And Medicinal Preparations, Deodourisers For Hygenic Purposes, Disinfectants (Medicated), Medicated Paper Napkins, Medicated Tissues, Medicated Soaps And Lotions, Medicated Nappies, Massage Oil (Medicated) All Included In Class 5.
[Class : 5] Pharmaceutical And Medicinal Preparation Being Antacid Preparation.
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[Class : 5] Pharmaceutical And Medicinal Preparations.
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[Class : 5] Medicinal And Pharmaceutical Preparations
["Trade mark is likely to be removed due to non filing of Renewal request within prescribed time limit In case of any discripancy contact respective TM Registry. "]
[Class : 3] Soaps, Toilet Preparations, Detergents, Cosmetics All Kinds Of Toileteries Dish Washing And Cleaning Preparations, Pre And After Shaving Lotions Room Deodourisers Other Than For Personal Use, Bath Salts, Bluing For Laundatory,
[Class : 3] Soaps, Toilet Preparations, Detergents, Cosmetics All Kinds Of Toileteries Dish Washing And Cleaning Preparations, Pre And After Shaving Lotions Room Deodourisers Other Than For Personal Use, Bath Salts, Bluing For Laundatory.
[Class : 31] Agricultuaral, Horicultural And Forestry Products And Grains Not Included In Other Classes; Living Animals, Seedings, Seeds, Natural Plants And Flowers Included In Class 31
[Class : 5] Pharmaceutical And Medicinal Preparations, Deodourisers For Hygenic Purposes, Disinfectants(medicated), Medicated Paper Napkins, Medicated Tissues, Medicated Soaps And Lotions, Medicated Nappies, Massage Oil (Medicated All Included) In Class 5.
[Class : 31] Agricultuaral, Horicultural And Forestry Products And Grains Not Included In Other Classes; Living Animals, Seedings, Seeds, Natural Plants And Flowers Included In Class 31
[Class : 5] Medicinal And Pharmaceutical Preparations[Class : 35] Services Of Marketing Distributors, Export And Import Retailers Of Medicinal And Pharmaceuticals Products And Kits; Services Of
Business Operations, Business Of Administration; Office Functions; Consultancies; Business Advisory Services; Managements; Advertising Services
[Class : 3] Perfumes, Soaps, Detergents, Shampoos, Cosmetics, Non Medicated Toilet Preparations, Hair Lotions Or Hair Styling Preparations, Deodorants, Depilatories, Anti Perspirant Preparations, Con Medicated Talcum Powder For Toiler Purposes, Sun Tanning Preparations (Cosmetics), Non Medicated Message Preparations, Bath Oils For Bath Salts, Not For Medical Purposes, Shavin...
[Class : 32] Beers, Aerated And Non Aerated Beverages, Mineral Waters And Non Alcoholic Drinks, Syrups, Extracts And Essence For Making Non Alcoholic Beverages, Concentrates, Juices, Squashes.
["Renewal of trademark is due. Renewal request in prescribed form is to be filed by the applicant. "]
[Class : 31] Agricultural , Horticultural And Forestry Products, And Grains Not Included In Other Classes, Living Animals, Fresh Fruits And Vegetables, Seeds, Live Plants And Flowers, Food Stuffs For Animals, Malt , Cattle And Poultry Feed, Wheat Bran, Potato And Onion.
[Class : 5] Medicinal And Pharmaceutical, Veterinary And Sanitary Substances, Diagnostic Preparations For Medicinal Purpose, Infants And Invalids Foods, Plasters, Material For Bandaging Materials, For Stopping Teeth, Dental Wax, Disinfectants, Preparations For Killing Weeds And Destroying Vermin.