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Pharmaceutical Combination Comprising A Selective S1 P1 Receptor Agonist

Abstract: The present invention relates to a pharmaceutical combination comprising a first active ingredient which is (R)-5-[3-chloro-4-(2,3-dihydroxy-propoxy)- benz[Z]ylidene]-2-([Z]- propylimino)-3-o-tolyl-thiazolidin-4-one or a pharmaceutically acceptable salt thereof and a second active ingredient which is selected from the group consisting of methyl fumarate, (N,Ndiethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, and 2- (2,5- dioxopyrrolidin-1-yl)ethyl methyl (2E)but-2-ene-1,4-dioate, or a pharmaceutically acceptable salt thereof.

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Patent Information

Application #
Filing Date
04 November 2022
Publication Number
48/2022
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
patent@depenning.com
Parent Application

Applicants

ACTELION PHARMACEUTICALS LTD.
Gewerbestrasse 16, CH-4123 Allschwil, Switzerland

Inventors

1. CLOZEL, Martine
c/o Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland
2. PIALI, Luca
Oberalpstrasse 13, CH-4054 Basel, Switzerland

Specification

Description:Please refer to the attachment. , Claims:Please refer to the attachment.

Documents

Application Documents

# Name Date
1 202248063164-AbandonedLetter.pdf 2023-12-26
1 202248063164-STATEMENT OF UNDERTAKING (FORM 3) [04-11-2022(online)].pdf 2022-11-04
2 202248063164-REQUEST FOR EXAMINATION (FORM-18) [04-11-2022(online)].pdf 2022-11-04
2 202248063164-FER.pdf 2022-12-23
3 202248063164-PROOF OF RIGHT [04-11-2022(online)].pdf 2022-11-04
3 202248063164-FORM 3 [14-11-2022(online)].pdf 2022-11-14
4 202248063164-COMPLETE SPECIFICATION [04-11-2022(online)].pdf 2022-11-04
4 202248063164-PRIORITY DOCUMENTS [04-11-2022(online)].pdf 2022-11-04
5 202248063164-POWER OF AUTHORITY [04-11-2022(online)].pdf 2022-11-04
5 202248063164-DECLARATION OF INVENTORSHIP (FORM 5) [04-11-2022(online)].pdf 2022-11-04
6 202248063164-FORM 18 [04-11-2022(online)].pdf 2022-11-04
6 202248063164-DRAWINGS [04-11-2022(online)].pdf 2022-11-04
7 202248063164-FORM 1 [04-11-2022(online)].pdf 2022-11-04
7 202248063164-FIGURE OF ABSTRACT [04-11-2022(online)].pdf 2022-11-04
8 202248063164-FORM 1 [04-11-2022(online)].pdf 2022-11-04
8 202248063164-FIGURE OF ABSTRACT [04-11-2022(online)].pdf 2022-11-04
9 202248063164-FORM 18 [04-11-2022(online)].pdf 2022-11-04
9 202248063164-DRAWINGS [04-11-2022(online)].pdf 2022-11-04
10 202248063164-DECLARATION OF INVENTORSHIP (FORM 5) [04-11-2022(online)].pdf 2022-11-04
10 202248063164-POWER OF AUTHORITY [04-11-2022(online)].pdf 2022-11-04
11 202248063164-COMPLETE SPECIFICATION [04-11-2022(online)].pdf 2022-11-04
11 202248063164-PRIORITY DOCUMENTS [04-11-2022(online)].pdf 2022-11-04
12 202248063164-PROOF OF RIGHT [04-11-2022(online)].pdf 2022-11-04
12 202248063164-FORM 3 [14-11-2022(online)].pdf 2022-11-14
13 202248063164-REQUEST FOR EXAMINATION (FORM-18) [04-11-2022(online)].pdf 2022-11-04
13 202248063164-FER.pdf 2022-12-23
14 202248063164-STATEMENT OF UNDERTAKING (FORM 3) [04-11-2022(online)].pdf 2022-11-04
14 202248063164-AbandonedLetter.pdf 2023-12-26

Search Strategy

1 SearchHistoryE_19-12-2022.pdf