Pre Erythrocytic Malaria Vaccines

Abstract: Pre-erythrocytic malaria vaccines with good preservation stability and immunostimulatory action are provided. According the present invention, combination use of a pharmaceutical composition comprising (4E,8E,12E,16E,20E)-N-{2-[{4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]benzyl}(methyl)amino]ethyl}-4,8,12,17,21,25-hexamethylhexacosa-4,8,12,16,20,24-hexaeneamide, or a pharmaceutically acceptable salt thereof, as a vaccine adjuvant with enhanced specific immune response against antigens and good preservation stability and a malaria vaccine with biological activity allow for the provision of pre-erythrocytic malaria vaccines with good preservation stability and immunostimulatory action.

Patent Information

Application #

Filing Date

25 January 2023

Publication Number

08/2023

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

patent@depenning.com

Parent Application

Applicants

PATH

2201 Westlake Avenue, Suite 200, Seattle, Washington 98121

SUMITOMO PHARMA CO., LTD.

6-8, Doshomachi 2-chome, Chuo-ku, Osaka-shi, Osaka 5410045

Inventors

1. KING, C. Richter

1840 Park Road NW, Washington, District of Columbia 20010

2. WU, Yimin

18133 Coachmans Road, Germantown, Maryland 20874

3. PLIESKATT, Jordan Lee

624 N Columbus Street Alexandria, Virginia 22314

4. THEISEN, Michael

Artillerivej 5 2300 Copenhagen S

5. SINGH, Susheel Kumar

Nedertoften 31, 1TV, Vanlose 2720 Copenhagen

6. FUKUSHIMA, Akihisa

c/o Sumitomo Pharma Co., Ltd., 1-98, Kasugadenaka 3-chome, Konohana-ku, Osaka-shi, Osaka 5540022

Specification

Documents

Application Documents

#	Name	Date
1	202347005027.pdf	2023-01-25
2	202347005027-STATEMENT OF UNDERTAKING (FORM 3) [25-01-2023(online)].pdf	2023-01-25
3	202347005027-Sequence Listing in txt [25-01-2023(online)].txt	2023-01-25
4	202347005027-Sequence Listing in PDF [25-01-2023(online)].pdf	2023-01-25
5	202347005027-PRIORITY DOCUMENTS [25-01-2023(online)].pdf	2023-01-25
6	202347005027-FORM 1 [25-01-2023(online)].pdf	2023-01-25
7	202347005027-DRAWINGS [25-01-2023(online)].pdf	2023-01-25
8	202347005027-DECLARATION OF INVENTORSHIP (FORM 5) [25-01-2023(online)].pdf	2023-01-25
9	202347005027-COMPLETE SPECIFICATION [25-01-2023(online)].pdf	2023-01-25
10	202347005027-FORM-26 [31-01-2023(online)].pdf	2023-01-31
11	202347005027-Proof of Right [16-02-2023(online)].pdf	2023-02-16
12	202347005027-Correspondence_Assignment_27-02-2023.pdf	2023-02-27
13	202347005027-Correspondence_Form 26_01-03-2023.pdf	2023-03-01