View All Documents & Correspondence
Purification Of Insulin
Abstract: The present application discloses a chromatographic process for separating protein components of a protein containing solution said solution comprising an insulin peptide and one or more di or polyvalent metal ions said insulin peptide being capable of self association and/or structural change in the presence of di or polyvalent metal ions said process comprising the steps of: a) applying the protein containing solution to a column of a chromatographic solid phase material wherein the loading of the insulin peptide is at least 6.0 g per litre of column volume (g/L ); and b)eluting the insulin peptide from said solid phase material by means of an eluent having a pH of at the most 8.5; and collecting a pool of the insulin peptide corresponding to at least 75 % by weight of the insulin peptide applied to the column in step (a).
Notices, Deadlines & Correspondence
Patent Information
Applicants
NOVO NORDISK A/S
Inventors
1. MOLLERUP Jørgen M.
2. FREDERIKSEN Søren Søndergaard
Specification
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 6435-CHENP-2013.pdf | 2013-08-08 |
| 2 | Signed Form 5.pdf | 2013-08-13 |
| 3 | Signed Form 3.pdf | 2013-08-13 |
| 4 | Signed Drawings.pdf | 2013-08-13 |
| 5 | 8189.204-IN, PCT IB 304.pdf | 2013-08-13 |
| 6 | 8189.204-IN, Form 2, Complete Specification.pdf | 2013-08-13 |
| 7 | 6435-CHENP-2013 FORM-3 24-01-2014.pdf | 2014-01-24 |
| 8 | 6435-CHENP-2013 FORM-1 24-01-2014.pdf | 2014-01-24 |
| 9 | 6435-CHENP-2013 CORRESPONDENCE OTHERS 24-01-2014.pdf | 2014-01-24 |
| 10 | 6435-CHENP-2013 FORM-3 06-02-2015.pdf | 2015-02-06 |
| 11 | 6435-CHENP-2013 CORRESPONDENCE OTHERS 06-02-2015.pdf | 2015-02-06 |
| 12 | 6435-CHENP-2013 POWER OF ATTORNEY 02-02-2016.pdf | 2016-02-02 |
| 13 | 6435-CHENP-2013 FORM-3 02-02-2016.pdf | 2016-02-02 |
| 14 | 6435-CHENP-2013 CORRESPONDENCE-F3-PA 02-02-2016.pdf | 2016-02-02 |
| 15 | Form 3 [01-08-2016(online)].pdf | 2016-08-01 |
| 16 | Form 26 [30-01-2017(online)].pdf | 2017-01-30 |
| 17 | Form 3 [08-02-2017(online)].pdf | 2017-02-08 |
| 18 | 6435-CHENP-2013-FORM 3 [04-08-2017(online)].pdf | 2017-08-04 |
| 19 | 6435-CHENP-2013-FORM 3 [08-02-2018(online)].pdf | 2018-02-08 |
| 20 | 6435-CHENP-2013-FER.pdf | 2018-03-28 |
| 21 | 6435-CHENP-2013-FORM 3 [08-08-2018(online)].pdf | 2018-08-08 |
| 22 | 6435-CHENP-2013-RELEVANT DOCUMENTS [17-09-2018(online)].pdf | 2018-09-17 |
| 23 | 6435-CHENP-2013-AbandonedLetter.pdf | 2018-11-05 |
Search Strategy
| 1 | 6435search_27-03-2018.pdf |