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Site Directed Mutagenesis Of Trem 1 Antibodies For Decreasing Viscosity
Abstract: Antibodies that are capable of specifically binding and preventing the activation of TREM-1, a protein expressed on monocytes, macrophages and neutrophils with both good affinity and low viscosity at clinically relevant concentrations are described. Such antibodies find utility in the treatment of individuals with an inflammatory disease, such as rheumatoid arthritis and inflammatory bowel disease.
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Notices, Deadlines & Correspondence
Notices, Deadlines & Correspondence
Patent Information
Application #
Filing Date
03 May 2023
Publication Number
29/2024
Publication Type
INA
Invention Field
BIOTECHNOLOGY
Status
Email
Parent Application
Applicants
NOVO NORDISK A/S
Novo Alle, 2880 Bagsvaerd, Denmark
Inventors
1. HENRIKSEN, Anette
Novo Nordisk A/S, Novo Alle, 2880 Bagsvaerd, Denmark
2. KJAERGAARD, Kristian
Novo Nordisk A/S, Novo Alle, 2880 Bagsvaerd, Denmark
3. WESTPHAL STENNICKE, Vibeke
Novo Nordisk A/S, Novo Alle, 2880 Bagsvaerd, Denmark
4. WIBERG, Charlotte
Novo Nordisk A/S, Novo Alle, 2880 Bagsvaerd, Denmark
Specification
Description:Attached , Claims:Attached
Documents
Application Documents
| # | Name | Date |
|---|---|---|
| 1 | 202318031577-STATEMENT OF UNDERTAKING (FORM 3) [03-05-2023(online)].pdf | 2023-05-03 |
| 2 | 202318031577-Sequence Listing in txt [03-05-2023(online)].txt | 2023-05-03 |
| 3 | 202318031577-Sequence Listing in PDF [03-05-2023(online)].pdf | 2023-05-03 |
| 4 | 202318031577-REQUEST FOR EXAMINATION (FORM-18) [03-05-2023(online)].pdf | 2023-05-03 |
| 5 | 202318031577-PRIORITY DOCUMENTS [03-05-2023(online)].pdf | 2023-05-03 |
| 6 | 202318031577-POWER OF AUTHORITY [03-05-2023(online)].pdf | 2023-05-03 |
| 7 | 202318031577-FORM 18 [03-05-2023(online)].pdf | 2023-05-03 |
| 8 | 202318031577-FORM 1 [03-05-2023(online)].pdf | 2023-05-03 |
| 9 | 202318031577-DRAWINGS [03-05-2023(online)].pdf | 2023-05-03 |
| 10 | 202318031577-DECLARATION OF INVENTORSHIP (FORM 5) [03-05-2023(online)].pdf | 2023-05-03 |
| 11 | 202318031577-COMPLETE SPECIFICATION [03-05-2023(online)].pdf | 2023-05-03 |
| 12 | 202318031577-Proof of Right [27-10-2023(online)].pdf | 2023-10-27 |
| 13 | 202318031577-FORM 3 [27-10-2023(online)].pdf | 2023-10-27 |
| 14 | 202318031577-FORM 3 [18-04-2024(online)].pdf | 2024-04-18 |