CLAIMS
1. A solid composition for oral administration comprising
(i) a GLP-1 derivative and dapagliflozin, or
(ii) a GLP-1 derivative and a salt of NAC in combination with an SGLT2
inhibitor.
2. A solid composition for oral administration comprising a GLP-1 derivative and dapagliflozin.
3. A solid composition for oral administration comprising a GLP-1 derivative, a salt of NAC, and empagliflozin.
4. The composition according to any one of the preceding claims, wherein said GLP-1 derivative has a size of no more than 12 kDa.
5. The composition according any one of the preceding claims, wherein said GLP-1 derivative is selected from the group consisting of semaglutide, Compound A, Compound B, Compound C, Compound D, and Compound E.
6. The composition according to any one of the preceding claims, wherein said GLP-1 derivative and/or dapagliflozin is in the form of a pharmaceutically acceptable salt, ester or solvate.
7. The composition according to any one of the preceding claims, wherein said composition comprises 5-300 mg SGLT2 inhibitor, 20-800 mg salt of NAC, such as SNAC, and optionally 0.1-100 mg GLP-1 derivative.
8. The composition according to any one of the preceding claims, wherein the dosage of said dapagliflozin is 0.5-50 mg per day and the dosage of said GLP-1 derivative is 0.1-100 mg per day.
9. The composition according to any one of the preceding claims, wherein said composition comprises one or more additional pharmaceutically acceptable excipients thereof.
10. The composition according to any one of the preceding claims, wherein said composition further comprises an absorption enhancer.
11. The composition according to any one of the preceding claims, wherein said absorption enhancer is a salt of NAC, such as SNAC.
12. The composition according to any one of the preceding claims, wherein said composition is in the form of a tablet, a capsule or a sachet.
13. The composition according to any one of the preceding claims, wherein the dosage of said composition administered is in the range of 200-1000 mg.

14. The composition according to any one of the preceding claims, wherein said composition is administered once daily.
15. The composition as defined in any one of the preceding claims for use in medicine.