THE INVENTION RELATES TO A NOVEL METHOD FOR THE PREPARATION PRODUCT OF FORMULA-I WHERE BY REACTING A NEW PRODUCT OF FORMULA-11

The present invention relates to an improved process for the preparation of o- . Ethoxybenzamidine hydrochloride in a cost effective and industrially feasible manner. The present invention relates to an improved process for the preparation of o- Ethoxybenzamidine   hydrochloride comprising   reduction   of  o-Eth...

This invention describes about novel 2,4-dihydro-6,8-dinitro-l-oxo- 2-substituted-[l,2,4]-triazolo [3,4-c][l,4] benzoxazine as derivatives of formula-I possessing diuretic activity superior to furosemide and hydrochlorothaizide. Where R is Na, K,l-4-alkyl or CH2-X where X is morpholine, piperidinyl or CH2OCOY wh...

A process for preparation of eletriptan hydrobromide having a-form of formula-I by reducing 3-(((R)-1-methylpyrrolidin-2-yl)methyl)-5-((E)-2-(phenylsulfonyl)vinyl)-1H-indole of formula-II in presence of a metal catalyst and converting to its hydrobromide salt.

ABSTRACT: The present invention relates to an improved process for the preparation of Tenofovir, and further conversion to Tenofovir Disoproxil or its pharmaceutically acceptable salts thereof comprising dealkylation of phosphonate ester of Formula 11(a), using halotrimethylsilane in the presence of a phase tran...

The objective of the present invention is to provide an improved process for the preparation of Imidapril that avoids the use of high pressure hydrogenation and gaseous hydrogen under pressure. There is provided a process for the preparation of 1-methyl-2-oxoimidazolidine-4-carboxylate of formula (II), the ...

The present invention relates to an improved process for the preparation of Crystalline Tadalafil Form A using solvent Acetic acid and anti-solvent Toluene resulting a high pure and consistent of Crystalline Tadalafil Form A.

The present invention provides a novel crystalline form of Eletriptan hydrobromide monohydrate. The present invention also relates to a process for the preparation of novel crystalline form of Eletriptan hydrobromide monohydrate.

The objective of the present invention is to provide an improved process for the preparation of Oxazolidinones of Formula (I): Oxazolidinones of Formula (I) represents antibiotic drugs Linezolid, Tedizolid, Radezolid, Eperezolid, Ranbezolid, Posizolid, Sutezolid and an anticoagulant Rivaroxaban. Particularly, th...

Synthesis of 6-hdyroxy-7-methozy quinazoline 4(3H) one, where in the quinazolinone derivative of formula - VII is prepared by converting iso vanillin (4-hydroxy-3-methoxy benzaldehyde) of formula-1 to a product of formula-II, nitrating the product of formula-II. to get a product of formula-III, conventing the produc...

Synthesis for quinazolinones of formula VII and its further conversion to an anti-cancer product, namely gefitinib of formula XIX, wherein reacting with 1-bromo-3-chloro propane to get hitherto unknown intermediate of formula XVIIIa, and converting the product formed of formula XVIII to product of XIX by reacting wi...

The present invention relates to a novel and environmentally safe and clean process for the of pharmaceutical grade anti-ulceratives, ranitidine and nizatidine, and an industrially significant by-product, thiophenol, comprising reacting a novel intermediate of formula I with a derivative of formula II in the prese...

The present invention relates to a process for the preparation of a novel product, 2-arylthio-2-methylamino-l-nitroethene, which in turn may be employed as a novel intermediate for the manufacture of anti-ulceratives like ranitidine and nizatidine.

The present invention provides an improved process for preparing 4-(4-methylpiperazin-1-yl)methyl benzoic acid dihydrochloride and its reaction with N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine amine in presence of DCC & HOBT to give imatinib. Imatinib is converted to its oxalate salt, reconverted to imatin...

The invention relates to a novel method for the preparation of imidapril hydrochloride of formula-I Formula-I by reacting esters of 4(S)-1-methyl-2-oxoimidazolidine-4-carboxylate of formula-II with (S)-ethyl-2-[(S)-4-methyl-2,5-dioxooxazolidin-3-yl]-4-phe...

The present invention reveals a novel process for the one of the key intermediates of eletriptan. The process involves heck coupling of the indole derivative with phenyl vinyl sulphone to render the corresponding product.

ABSTRACT The present invention relates to novel and improved process for preparing a Azole Antifungal agent or its pharmaceutically acceptable salts. The present invention more " particularly relates to novel and improved process for preparing Luliconazole or its pharmaceutically acceptable salts. ...

NOT SUBMITTED

INTERMEDIATE OF IBUPROFEN The present invention provides a simple, cost effective, improved and robust process for the preparation of compound of formula I which is used as an intermediate in the preparation of Ibuprofen or its salts, wherein the process is simple and cost effective.

Not Submitted

ABSTRACT: Present invention relates to a process for the preparation of Tenofovir by dealkylatioh of its phosphonate esters using Urea, Thiourea Or Guanidine, through the formation of Tenofovir- adduct, followed by hydrolysis using an acid.

The present invention relates to an improved process for the preparation of Raltegravir compound of Formula (I) Formula (I) or its salts using an intermediate compound of Formula (II) Formula (II) or its salts, wherein Rj, and Rj' are independently selected from hydrogen, alkyl or N-protecting group, R3 is selecte...

The present invention relates to an improved process for the preparation of Apixaban intermediate compound of Formula (I) wherein R1 is selected from halo, nitro, amino, N-protected amino, N-acyl optionally substituted with halo groups.

The present invention relates to an improved process for the purification of Luliconazole using mixture of alcohols which is highly cost effective, commercially feasible & industrially advantageous.

The present invention provides a simple, cost effective, improved and robust process for the preparation of Macitentan of Formula I.yielding, at a high yield with high purity without formation of undesired impurities.

The present invention is. to provide a simple, cost effective, improved and robust process for ' tke .preparation of Rizatriptan intermediate 4-((lH-l,2,4-triazol-l-yr)methyl)benzeiiarnine compound of Formula-I yielding at a high yield with high purity without formation of undesired impurities. ...

ABSTRACT The. present invention relates a simple, cost effective, improved and robust process for the preparation of Dabigatran intermediate Ethyl-3-[[3-amino-4-(nrethy].arilino)bcnzoyi]-p)Tidiri-2iylarniho]propanoate compound of Formula-I yielding at a high yield with high purity without formation of undesired imp...

The present invention relates to improved process for the purification of Brexpiprazole compound of Formula I using Brexpiprazole phosphate salt.

Not submitted

ABSTRACT NOVEL POLYMORPHS OF ELAGOLIX SODIUM The present invention relates to novel mixture of amorphous and crystalline polymorph of Elagolix Sodium salt & its use in the preparation of pure Elagolix.

The present invention relates to novei. crystalline polymo.rph of Luliconazole HBr salt & its use in the preparation of chiraliy pure Luliconazole.

The present invention provides crystalline Ranitidine hydrochloride Form 2 with a residual isopropanol solvent below 100 ppm and contains NDMA impurity less than 0.05 ppm as measured by LC-MS/MS method.

ABSTRACT The present invention relates a simple, cost effective, improved and robust process for the preparation of Dabigatran Etexilate from Dabigatran using imidazole as a coupling agent.

The present invention provides an improved process for the preparation of compound of Formula II which is free of Impurity A wherein the reaction is carried out in the presence of inorganic base.

The present invention relates to novel crystalline polymorph of Lanoconazole HBr salt & its use in the preparation of pure Lanoconazole.