The present invention relates to an improved and economical process for enantioselective synthesis and purification of a novel key intermediate of Brivaracetam. Further, the present invention also relates to a process for the preparation of a chirally pure Brivaracetam of formula I utilizing the said intermediate.
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ABSTRACT
A NEW COST EFFECTIVE AND SCALABLE PROCESS FOR SYNTHESIZING PURE BRIVARACETAM
The present invention relates to novel, economical processes for the preparation of enantiomerically pure Brivaracetam of Formula I having 99-100% diastereomeric excess (de) from its (R)-lactone intermediate that is (4R)-4-pr...
ABSTRACT
A PROCESS FOR THE PREPARATION OF 1-AMINO-4-CYCLOPENTYLPIPERAZINE
The present invention provides an improved process for the preparation of 1-amino-4-cyclopentylpiperazine represented by formula (I) below:
(I)
FIGURE 1