The present invention provides an improved process for the preparation of 4-bromo-7H-pyrrolo [2.3-d] pyrimidine compound of Formula I by coupling 2-bromo-l,l-dimethoxyethane with ethyl-2-cyanoacetate to obtain ethyl-2-cyano-4,4-dimethoxybutanaote compound of formula II which condenses to 7H- Pyrrolo [2,3-d] pyrimidi...

The present invention provides an improved process for the manufacturing of 2,4-dichloro-7H-pyrrolo [2,3-d] pyrimidine compound of Formula I by coupling of Chloro acetaldehyde dimethyl acetal or Bromo acetaldehyde dimethyl acetal with 6- amino uracil to obtain 1H- pyrrolo[2,3-d] pyrimidine-2,4(3H,7H)- dione compound...

ABSTRACT ENVIRONMENT FRIENDLY PREPARATION METHOD OF 6-METHOXYPYRIDAZIN-3-AMINE An environment friendly preparation method of 6-methoxypyridazin-3-amine compound having Formula I by amination of 3,6-dichloro pyridazin in presence of aqueous ammonia to give 6-chloropyridazin-3-amine followed by conversion of 6-chlor...

An improved process for the process of the preparation of 2-[(4 bromophenyl)(methoxy)methylene]malononitrile compound of Formula I, which comprises of, chlorination of 5-bromobenzoic acid compound of Formula IV With oxalyl chloride in the presence of a dichloromethane to give in-situ compound of 5-bromobenzoy...