The present disclosure relates to a process for preparing 4-(4-aminophenyl)morpholin-3-one with high purity. 4-(4-aminophenyl)morpholin-3-one (I) is an intermediate used for preparing Rivaroxaban, an anti-coagulant drug. The present disclosure employs mild reaction conditions, and readily available reagents that are...

The present disclosure relates to a process for preparing 5-halo-2,3-diphenylpyrazine. The process comprises reacting benzil (II) with glycinamide hydrochloride (III) and a base to form 5,6-diphenylpyrazin-2-ol (IV) which is halogenated using a halogenating agent in the presence of N,N-dimethyl aniline to obtain 5-h...

The present disclosure relates to a process for preparing 2,4-dimethylthiophenol. The process of the present disclosure involves chlorosulphonation of 1,3-xylene (II) at a temperature in the range of 0 °C to 30 °C, to obtain a 2,4-dimethylbenzenesulphonyl chloride (IV), which is reduced in the presence of a mineral ...

The present disclosure relates to a process for preparing 6-methoxycarbonyl-2-oxindole (I). The process of the present disclosure involves mild reaction conditions, having convenient operations, easy purification steps, and hence environment friendly and economic. 6-methoxycarbonyl-2-oxindole (I) can be used as an i...

The present disclosure relates to a process for preparing 3-morpholino-1-(4-(2-oxopiperidine-1yl)-phenyl)-5, 6-dihydro pyridine-2-one. The process of the present disclosure involves hydrogenating 3-chloro-1-(4-nitrophenyl)-5,6-dihydropyridine-2-one to obtain 3-chloro-1-(4-amino phenyl)-5,6-dihydropyridine-2-one, whi...

ABSTRACT A PROCESS FOR PREPERATION OF 4-ISOBUTOXYBENZYLAMINE ACETATE The present disclosure relates to a process for preparing 4-isobutoxybenzylamine acetate. The process of the present disclosure is simple and provides 4-isobutoxybenzylamine acetate with a comaparatively high yield and high purity. ...

ABSTRACT A PROCESS FOR PREPARATION OF 4-METHYLENEPIPERIDINE HYDROCHLORIDE The present disclosure relates to a process for preparing 4-methylene piperidine hydrochloride. The process comprises alkylating 1-benzylpiperidine-4-one using an alkylating agent in the presence of an alkali and a first fluid medium to obta...

The present disclosure relates to a process for preparing 2,3-dihydro-1,4-benzodioxine-6-carbaldehyde. The process of the present disclosure involves dealkylation of 4-hydroxy-3-methoxybenzaldehyde to obtain 3,4-dihydroxybenzaldehyde which is subjected for etherification reaction to obtain 2,3-dihydro-1,4-benzodioxi...

ABSTRACT A PROCESS FOR THE PREPARATION OF 2-(PIPERIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE The present disclosure relates to a process for the preparation of 2-(piperidin-4-yl)-1H-benzo[d]imidazole. The process of the present disclosure provides (piperidin-4-yl)-1H-benzo[d]imidazole with comparatively high yield and high p...