A composition for promoting hair sprouting and hair growth according to the present invention contains a higher content of ginsenoside Rb2 Rc and Rg1 and thus can provide better hair sprouting and hair growth effects compared to hair growth agents manufactured by existing techniques. Also the composition is made ver...

The present invention relates to a novel benzoic acid amide derivative compound isomers thereof pharmaceutically acceptable salts thereof prodrugs thereof hydrates thereof or solvates thereof. The novel compound has excellent skin whitening effects.

This specification relates to a method for preparing substituted pyridine by using ammonium carbamate as a nitrogen source to prepare enamine as an intermediate compound and thereafter reacting the same with other compounds again. According to the method of the present specification it is possible to prepare substit...

The present specification relates to a chiral resolution method of a stereoisomer mixture, comprising a step of mixing a stereoisomer mixture of compounds, in which an amine group is bound to an asymmetric carbon atom, with a chiral auxiliary and saltforming auxiliary compound, wherein the chiral auxiliary is an ...

The present invention relates to a cosmetic device using high frequency waves for injecting pharmaceutical cosmetic compositions wherein the device comprises: a transmitting unit for high frequency waves which transmits high frequency waves supplied from an external high frequency wave generating source; and an inj...

The present invention relates to a composition containing a chemokine, particularly, an interferon-inducible T-cell alpha chemoattractant (ITACT) which can decrease the gene expression of a factor related to melanin pigment production in melanocytes, thereby exhibiting a skin whitening effect. ...

The present invention relates to a nozzle device and a minimally invasive injection device. According to one embodiment of the present invention the nozzle device for a minimally invasive injection device comprises: an outlet for forming a micro jet of liquid; and a micro sized injection portion connected to the out...

Disclosed are a novel compound acting as a cannabinoid receptor 1 inhibitor a prodrug thereof a pharmaceutically acceptable salt thereof and a hydrate thereof or a solvate thereof. The novel compound or the like is useful for preventing or treating diseases mediated by cannabinoid receptor 1.

The present invention relates to a cosmetic composition containing gulfweed extract, sea staghorn extract, and brown seaweed extract as active ingredients, and more particularly, to a cosmetic composition which contains one or more kinds of extracts selected from the group consisting of gulfweed extract, sea st...

Disclosed is a controlled-release microparticle: including a matrix comprising a pharmacologically active component; and a controlled-release layer comprising a substance which forms a controlled-release stratum on the matrix. The disclosed controlled-release microparticie not only allows effective dual release ...

The fragrance composition of Citrus flowers according to the present invention is produced by respectively adding jasmone and β-caryophyllene to linalool, myrcene, nerolidol, methyl anthranilate or the like which have been analysed to be aromatic components of the flowers of Citrus unshin and the flowers of Citrus n...

The present invention relates to a cosmetic composition carrier in which one or more foams having a number of pores in the range of 10ppi to 130ppi are impregnated with a cosmetic composition having a viscosity of 1,000 to 5,000cps and 15,000 to 100,000 cps so as to enable a user to carry a compact type liquid cosme...

Disclosed is a cosmetic composition carrier having a viscosity of 1,000 to 5,000 centipoise (cps) or 15,000 to 60,000 cps. The cosmetic composition carrier comprises a urethane foam having a hardness before impregnation of 1 to 100 on the Asker durometer type F.

This present disclosure relates to novel compounds, isomer thereof or pharmaceutically acceptable sailts thereof as vanilloid receptor (Vanilloid Receptor 1 VR1; TRPVl )antagonist; and a pharmaceutical composition containing the same. The present disclosure provides a pharmaceutical composition for preventing or tr...

The present invention relates to a cosmetic composition which contains jade powder so as to block blue light in the visible spectrum. The composition containing jade powder as an active ingredient for blocking blue light is capable of specifically reflecting and thus blocking light in the blue light spectrum which h...

The present invention relates to titanium dioxide composite powders and a base makeup composition containing the same, more specifically to: titanium dioxide composite powders which are produced by mixing titanium dioxide with elastomers, coating the mixture with polymethylsilsesquioxane, and applying the coated mix...

Provided is a composition for preventing hair loss or for stimulating hair growth, containing valproic acid or the pharmaceutically acceptable salts thereof as active ingredients. The composition can be used in various fields such as pharmaceuticals, cosmetics, and beauty treatments.

The present invention relates to a skin-whitening cosmetic composition, and more particularly, to a skin-whitening cosmetic composition containing a Commiphora   mukul   resin extract and a Terminalia   chebula   extract.  The present invention also relates to a cosmetic composition containing a Commiphora muku...

Provided is a polyether-based urethane foam for impregnating a cosmetic composition. The polyether-based urethane foam has excellent touch feel  portability and stability.

2-cyclopenten-1-one oxime derivatives represented by Formula (I), or pharmaceutically acceptable salts thereof inhibit the production of TNF-α or PDE4, and therefore show therapeutic effect in inflammatory or immunological disorders mediated through TNF-α or PDE4.

A controlled release preparation which comprises particles containing 5cilostazol or its pharmaceutically acceptable salt dispersed in a solubilizing agent and an erodible material encasing said particles which is capable of forming a hydrogel, can maintain a constant level of cilostazol in the blood through its ...

The present invention relates to a method for preparing a benzoic acid amide compound in a high yield by presenting a novel method for preparing a benzyl amine compound to be used as a reactant and delimiting the reaction condition of each step by using the same and the method is economically advantageous since mass...

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor I; VRI; TRPVI) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treat...

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor I; VRI; TRPVI) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treat...

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPVl)antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treat...

The present invention provides a method for preparing a Broussonetia kazinoki extract  comprising the following steps: solvent extracting Broussonetia kazinoki; isolating the Broussonetia kazinoki extract  extracted in the previous step; and crystallizing the Broussonetia kazinoki extract isolated in the previous st...

The present invention relates to polymeric Microparticulates for sustained release of drug and to the process for the preparation thereof. The process of the present invention for preparing polymeric Microparticulates based on microcoagulation phenomenon of water-soluble polymer not only improves loading amount of d...

Disclosed are a cosmetic composition carrier containing a urethane foam layer structure and cosmetics including the cosmetic composition carrier that contains a cosmetic composition.

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treat...

Disclosed in the present specification is a method capable of preparing N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide (INT028-2) with high optical purity, through the selection of Ellman-chiral auxiliaries and the re-crystallization and separation of optical isome...

The present invention relates to a chiral resolution method for a stereoisomeric mixture the method comprising a step for mixing a stereoisomeric mixture of a compound in which an amine group is attached to an asymmetric carbon atom and a chiral auxiliary. Here the chiral auxiliary is 23-dibenzoyl-tartaric acid or O...

The present invention relates to a method for preparing N (4 acetyl 2 6 difluorophenyl)methanesulfonamide the method comprising a step of reacting 3 4 5 trifluoroacetophenone and methanesulfonamide in the presence of a nitrile solvent. The preparation method of the present invention enables a high yield of INT 1 to ...

Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apoptosis of melanocyte...