The present invention relates to an industrially feasible, robust, and economically viable process for preparation of ethyl 2-[(2,6-difluoro-benzyl)-ethoxycarbonyl-amino]-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate (1).

The present invention relates to an industrially feasible, robust, and economically viable process for preparation of 3-ethylbicyclo [3.2.0] hept-3-en-6-one (7). The process produces compound (7) having chiral purity >99%.

The present invention relates to substantially pure ethyl 2-(5-amino-2-bromo-4- fluorophenyl) acetate of formula (1) having undesired impurity of formula (5) less than 0.2%. The invention further relates to a process for the preparation of substantially 10 pure ethyl 2-(5-amino-2-bromo-4-fluorophenyl) acetate of ...