NOT SUBMITED

The process envisaged according to the invention provides for the synthesis of zopiclone using combination of bases, such as, triethyl amine and N,N-dimethylamino pyridine in methylene chloride.

The process for producing 2-[1-(hydroxymethyl)-cyclopropane] acetic acid with steps of: a) reacting 1,1-cyclopropanedimethanol with aldehydes or acetals of aldehydes in solvents or without solvent using acidic catalyst at elevated temperature with azeotropic removal of water to form benzylidene acetal; b) opening of...

The method for producing a 5-bromo-N-(4, 5-dihydro-1H/-imidazol-2-yl)- 6-quinoxalinamine (Brimonidine) formula (I) and it's tartrate salt having therapeutic indication as regulators of the cardiovascular system and, in particular, in the treatment of hypertension; Comprises a contacting a 6-amino-5-brmquinoxaline wi...

An improved 7-(4-bromobutoxy)-3,4-dihydro-2 (1H)-quinolinone, an intermediate of Aripiprazole and a process therefore having better yield and high purity and a process for the manufacture of the same by reacting the quinolinone with dibromobutane in the presence of a phase transfer catalyst under basic condition eit...

An improved process for preparation of Glucosamine:Ibuprofen complex (Formula-I) comprises addition of pulverized ibuprofen to halide free glucosamine in water at temperature 0-5 °C for 48 hrs which furthermore treated with water and followed by cyclohexane to obtain solid , moister free and stable Glucosamine : Ibu...

The invention disclosed process for preparation of 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo-[3,4-b] pyrazin-5-yl-4-methyl piperazine-1-carboxylate also known as zopiclone. The invention further describes an effective method for resolution of zopiclone into its diastereomers and also provides a method of...

A process for producing Zaleplon comprising: (a)reacting N-[3-[3-arylamino)-1-oxo-2-propeny1)pheny1]-N-ethy1 acetamide with 3-amino-4-cyanopyrazole hydrochloride in aqueous acetic acid containing acids. (b)water in to the said acetic in the range of 10% to 90% and preferably between 30 to 60%; and (c)The temperat...

An improved process for preparation of triazol-Benzodiazepine derivatives like Alprazolam, Triazolam, brotizolam and Etizolam comprises a cyclization reaction of compound formula –B in toluene with catalytic amount of aliphatic or aromatic sulphonic acid or sulphuric acid to obtain compound formula (A) : X is hydro...

An improved process for the synthesis of aripiprazole and furthermore an isolation process of 7-(4-bromobutoxy)-3, 4-dihydro-2 (lH)-quinolinone (IV) is simplified. The aripiprazole prepared from this improved process has a better purity and comparable yields with respect to prior art