Reprogrammed somatic cells  methods for reprogramming  reprogramming factors for somatic cells and uses of such factors and cells are described. Nuclear reprogramming factors [NRF] described comprise one or more of a gene product or a polynucleic acid encoding a gene product from a retinoic acid receptor (RAR/RXR) f...

A monitoring method comprising identifying a somatically acquired genomic rearrangement associated with a disease state in a patient by genome wide analysis of the nucleic acid of that patient and monitoring the changes in levels of nucleic acid containing the genomic rearrangement and/or quantifying the levels of n...