ABSTRACT The present invention is in the technical field of nanoparticle delivery system, in particular, a self-assembling reconstituted high density lipoprotein complex comprising a combination of: a pH-specific polymer, a cross linker, a receptor binding component (R), and a drug (D); wherein the pH-specific po...

ABSTRACT The present disclosure relates to cancer therapeutics, in particular, the invention relates to the use of Curcumin and Metformin in chemoprevention of cancers, including head and neck cancers. The use of this said combination of drugs in a pre-clinical carcinogenesis model has resulted in lower number of...

CXCR4 INHIBITOR IN REVERSING RESISTANCE TO CHEMOPREVENTION AND CHEMOTHERAPY ABSTRACT The present disclosure deals with compounds, compositions, methods to prevent, inhibit and/or treat cancer, and methods to promote Cancer Stem Cell (CSC). In particular, the invention relates to, CXCR4 inhibitor AMD in reversin...

The present disclosure relates to a nanoparticle based biosensor for cell detection and isolation system, more particularly to isolate selective cell types possessing specific surface receptors from a heterogeneous cell population consisting of varied cell types bearing wide array of receptors. Furthermore, inventio...

ABSTRACT SALIVARY PROTEIN BIOMARKERS FOR THE DIAGNOSIS AND PROGNOSIS OF HEAD AND NECK CANCERS, AND PRECANCERS The present disclosure relates to a panel of biomarkers for the detection/diagnosis and prognosis of head and neck squamous cell carcinoma (HNSCC). Biomarkers for the detection/diagnosis of carcinoma c...

MOLECULAR MARKER BASED ORAL CYTOLOGY FOR DETECTION OF POTENTIALLY MALIGNANT AND MALIGNANT ORAL LESION ABSTRACT The present disclosure relates to a minimally invasive, molecular marker-based cytology method for the detection/diagnosis of oral potentially malignant (OPML) and malignant lesions. In particular, the ...

SYSTEMS AND METHODS FOR ANALYZING SEQUENCE DATA ABSTRACT The present invention relates to systems, methods, software and computer-usable media comprising a clustering tool for biomolecule-related sequence. Biomolecule-related sequences can relate to proteins, peptides, nucleic acids, and the like, and can incl...

The present invention is in the technical field of a pharmaceutical composition comprising recombinant polypeptides; wherein the first recombinant polypeptide comprises a genetically modified ACE2 protein to increase binding to SARS-CoV and SARS-Cov2 viruses spike protein and neutralizing activity; and the second re...

The present disclosure relates to a tumor microenvironment platform comprising oral carcinoma for predicting drug sensitivity, drug resistance and disease progression. More particularly, invention focuses on a method for obtaining a tumor microenvironment platform comprising oral carcinoma for predicting chemoresist...

ABSTRACT SYSTEM AND METHOD COMPRISING EXPRESSION MAPS FOR PROGNOSTICATING EARLY-STAGE ORAL CANCER The disclosed embodiment relates to a system and method comprising expression maps for prognosticating early-stage oral cancer. More particularly, it involves the identification of specific CSC markers that are in spe...

ABSTRACT 3D MODEL FOR TUMOUR MICROENVIRONMENT ANALYSIS The present disclosure relates to a system for 3D model for tumour microenvironment analysis. More particularly, the system is for analysis and prediction assay of clinical response for a subject upon targeting with radiotherapy and chemotherapy. Furthermore...

ABSTRACT SYSTEM FOR IN-VITRO MODELLING OF NODAL METASTASIS IN ORAL SQUAMOUS CELL CARCINOMA The present invention disclosure relates to a system for In-vitro modeling of nodal metastasis in oral squamous cell carcinoma. More particularly, the invention deals with the system and method for analysis and drug testin...

ABSTRACT SYSTEM COMPRISING ARTIFICIAL INTELLIGENCE INTEGRATED MOLECULAR CYTOLOGY AND RADIOLOGY FOR TRIAGING OF THYROID NODULES The disclosed embodiment relates to a composition and system comprising Artificial Intelligence integrated molecular cytology and radiology for triaging of thyroid nodules. More particular...