Novel Salt Forms Of A 4 H Pyran 4 One Structured Cyp11 A1 Inhibitor

Orion Corporation
Reply Not Filed App No 202317058209 Chemical

Patent information

IP India · live record
Application number
202317058209
Filing date
30 August 2023
Status
Reply Not Filed
Publication number
49/2023
Publication type
INA
Invention field
Chemical

Abstract

The present invention relates to novel salts, particularly crystalline salts, of 2-(isoindolin-2-ylmethyl)-5-((1-(methylsulfonyl)piperidin-4-yl)methoxy)-4H-pyran-4-one (I) which are particularly suitable for use in the manufacture of pharmaceutical 5 compositions. Furthermore, the invention relates to pharmaceutical compositions comprising such novel salts. Compound (I) is a selective inhibitor of CYP11A1 enzyme and is useful in the treatment of hormonally regulated cancers, such as prostate cancer and breast cancer.

Applicants

1
Finland
ORION CORPORATION Orionintie 1 FI-02200 Espoo

Inventors

7
Finland
KARJALAINEN, Oskaric/o FERMION OY Koivu-Mankkaan tie 6 FI-02200 Espoo
Finland
MÄKELÄ, Mikkoc/o ORION CORPORATION P.O.Box 65 FI-02101 Espoo
Netherlands
POP, MihaelaLe Tourmalet 14 1060NX AMSTERDAM
Finland
RUMMAKKO, Petteric/o ORION CORPORATION P.O.Box 65 FI-02101 Espoo
Denmark
SHEVCHENKO, AnnaAgern Allé 3 2970 HORSHOLM
Finland
SINERVO, Kaic/o ORION CORPORATION P.O.Box 65 FI-02101 Espoo
Finland
TIAINEN, EijaRuutikatu 3 A 17 FI-02650 ESPOO

Documents

Sign in to open
Application documents
1 202317058209-STATEMENT OF UNDERTAKING (FORM 3) [30-08-2023(online)].pdf 30 Aug 2023
2 202317058209-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [30-08-2023(online)].pdf 30 Aug 2023
3 202317058209-FORM 1 [30-08-2023(online)].pdf 30 Aug 2023
4 202317058209-DRAWINGS [30-08-2023(online)].pdf 30 Aug 2023
5 202317058209-DECLARATION OF INVENTORSHIP (FORM 5) [30-08-2023(online)].pdf 30 Aug 2023
6 202317058209-COMPLETE SPECIFICATION [30-08-2023(online)].pdf 30 Aug 2023
7 202317058209-Proof of Right [17-10-2023(online)].pdf 17 Oct 2023
8 202317058209-FORM-26 [19-10-2023(online)].pdf 19 Oct 2023
9 202317058209-FORM 3 [27-02-2024(online)].pdf 27 Feb 2024
10 202317058209-FORM 18 [06-02-2025(online)].pdf 06 Feb 2025
11 202317058209-FER.pdf 10 Aug 2026
Search strategy
1202317058209_SearchStrategyNew_E_IPSearchHistory-20260807E_07-08-2026.pdf