Tead Inhibitors

Abstract: The present invention relates to a compound of formula (I) wherein A, Z, L, R1, R2, R3, R4, R5 and R33 are as defined in claim 1, or a pharmaceutically acceptable salt thereof. The compounds of formula (I) possess utility as inhibitors of TEAD. The compounds are useful as medicaments in the treatment of diseases or conditions wherein inhibition of TEAD is desired, such as cancer and chronic pain.

Patent Information

Application #

Filing Date

26 October 2023

Publication Number

37/2024

Publication Type

INA

Invention Field

CHEMICAL

Status

Email

Parent Application

Applicants

ORION CORPORATION

Orionintie 1 FI-02200 Espoo

Inventors

1. AHLMARK, Marko

c/o ORION CORPORATION P.O.Box 65 FI-02101 Espoo

2. DIN BELLE, David

c/o ORION CORPORATION PO Box 65 FI-02101 Espoo

3. NOUTSIAS, Dimitris

c/o ORION CORPORATION P.O.Box 65 FI-02101 Espoo

4. PIETIKÄINEN, Pekka

c/o ORION CORPORATION PO Box 65 FI-02101 Espoo

5. RUMMAKKO, Petteri

c/o ORION CORPORATION P.O.Box 65 FI-02101 Espoo

6. SIPILÄ, Julius

c/o ORION CORPORATION PO Box 65 FI-02101 Espoo

7. WOHLFAHRT, Gerd

Chausseestrasse 121 10115 Berlin

Specification

Documents

Application Documents

#	Name	Date
1	202317072936-TRANSLATIOIN OF PRIOIRTY DOCUMENTS ETC. [26-10-2023(online)].pdf	2023-10-26
2	202317072936-STATEMENT OF UNDERTAKING (FORM 3) [26-10-2023(online)].pdf	2023-10-26
3	202317072936-FORM 1 [26-10-2023(online)].pdf	2023-10-26
4	202317072936-DECLARATION OF INVENTORSHIP (FORM 5) [26-10-2023(online)].pdf	2023-10-26
5	202317072936-COMPLETE SPECIFICATION [26-10-2023(online)].pdf	2023-10-26
6	202317072936-FORM-26 [03-01-2024(online)].pdf	2024-01-03
7	202317072936-Proof of Right [01-04-2024(online)].pdf	2024-04-01
8	202317072936-FORM 3 [01-04-2024(online)].pdf	2024-04-01
9	202317072936-FORM 18 [13-03-2025(online)].pdf	2025-03-13