Description:FIELD OF THE INVENTION
[0001] The present disclosure relates generally to the field of pesticidal composition. Particularly, the present disclosure provides a pesticide composition for controlling various indoor and outdoor pests.

BACKGROUND
[0002] Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention, or that any publication specifically or implicitly referenced is prior art.
[0003] The most numerous and successful animals on earth are undoubtedly insects. Despite some helpful species, a great many insects are a bane to humans. Many months of the year, people venturing outdoors are plagued by biting insects, such as mosquitoes, gnats, noseeums (biting midges), flies, ticks, head lice, fire ants, fleas, and other insects. The bites and stings inflicted by “biting” insects are often itchy, can become infected and subsequently may prove fatal to the subject.
[0004] Almost everyone in their life has had the unpleasant experience of being bitten by a mosquito. Mosquito bites can cause skin irritation through an allergic reaction to the mosquito's saliva - this is what causes the red bump and itching. They are the vectors responsible for transmitting serious and life-threatening diseases such as malaria, dengue, yellow fever, chikungunya and lymphatic filariasis.
[0005] Numerous devices, agents, compositions, and formulations are already reported in the literature and are commercially available, capable of repelling, killing, or reducing the number of mosquitoes in a premise. However, these devices, agents/formulations still suffer from certain limitations such as being expensive, ineffective and exhibiting certain side-effects such as irritation, allergy, uneasiness, reduction in oxygen content, etc.
[0006] There is, therefore, need in the art to develop new and improved compositions that repel, kills, prevent, reduce and control various indoor and outdoor pests, and overcomes one or more problems associated with the conventional compositions/formulations thereof. The present invention satisfies the existing as well as other needs.

OBJECTS
[0007] Primary object of the present disclosure is to provide a pesticide composition that overcomes one or more limitations associated with the conventional pesticide compositions/formulations.
[0008] Another object of the present disclosure is to provide a pesticide composition for repelling and/or reducing and/or controlling various indoor and outdoor pests.
[0009] Another object of the present disclosure is to provide a pesticide composition for repelling and/or reducing and/or controlling the population of mosquitoes.
[00010] Another object of the present disclosure is to provide a pesticide composition that exhibits high repellence and pesticidal activity.
[00011] Another object of the present disclosure is to provide a pesticide composition that is safe and free of side-effects such as irritation, allergy, uneasiness, reduction in oxygen content, etc.
[00012] Another object of the present disclosure is to provide a pesticide composition that exhibits superior storage stability and synergistic activity /functional reciprocity.
[00013] Another object of the present disclosure is to provide a pesticide composition that is easy to prepare and economical.
[00014] Other objects of the present invention will be apparent from the description of the invention herein below.

SUMMARY
[00015] The present disclosure relates generally to the field of pesticidal composition. Particularly, the present disclosure provides a pesticide composition for controlling various indoor and outdoor pests.
[00016] An aspect of the present disclosure relates to a pesticide composition for controlling indoor and outdoor pests, said composition including: Pimenta dioica in an amount ranging from 1% to 40% by weight of the composition; Pogostemon cablin in an amount ranging from 1% to 40% by weight of the composition; and rest being an excipient. In an embodiment, Pimenta dioica is present in an amount ranging from 1.5% to 35% by weight of the composition; Pogostemon cablin is present in an amount ranging from 1.5% to 35% by weight of the composition; and rest being an excipient. In an embodiment, the excipient is selected from any or a combination of a perfume, a preservative, an adhesive, a smoldering agent or a burning aid, a binder, a filler or a burnable base, a propellant, a solvent, a wetting agent, a solubilizer, a hardening agent, an emulsifier, a diluent, a lubricant, a colouring agent, a lower alcohol, and a neutralization base. In an embodiment, the composition is formulated into a liquid form, a semi-solid form, a solid form, a gel or a gaseous form. In an embodiment, the composition is formulated into a cream, a lotion, an ointment, a gel, a spray, a vaporizer, a paste, a powder, a dust, a wax, a chalk, granules, pellets, a burn paper, a coil, an incense stick, pellets, a bait, cordages, a candle, a sealing agent, a caulk, a patch, a bait, a mat, a filler, a wood filler, a self-ignite formulation, a mist, a liquid vaporizer, an aerosol, an emulsion, a suspension, a micro-emulsion, a varnish dispersion, a fumigant, or a solution.
[00017] Another aspect of the present disclosure relates to a liquid or a semisolid pesticide formulation for controlling indoor and outdoor pests, said formulation including: Pimenta dioica in an amount ranging from 1% to 40% by weight of the formulation; Pogostemon cablin in an amount ranging from 1% to 40% by weight of the formulation; and rest being an excipient. In an embodiment, the liquid or a semisolid formulation includes a cream, a lotion, an ointment, a gel, a spray, a vaporizer, a paste, a mist, a liquid vaporizer, an aerosol, an emulsion, a suspension, a micro-emulsion, a varnish dispersion, a fumigant, or a solution.
[00018] Still another aspect of the present disclosure relates to a solid pesticide formulation for controlling indoor and outdoor pests, said formulation including: Pimenta dioica in an amount ranging from 1% to 40% by weight of the formulation; Pogostemon cablin in an amount ranging from 1% to 40% by weight of the formulation; and rest being an excipient. In an embodiment, the solid formulation includes a granule, a paste, a powder, a dust, a wax, a chalk, pellets, a burn paper, a coil, an incense stick, pellets, a bait, cordages, a candle, a sealing agent, a caulk, a patch, a bait, a mat, a filler, a wood filler, a self-ignite formulation, or a vaporizer.
[00019] Other aspects, advantages, and salient features of the invention will become apparent to those skilled in the art from the following detailed description, which is taken in conjunction with the exemplary embodiments of the invention.

DETAILED DESCRIPTION
[00020] The embodiments herein and the various features and advantageous details thereof are explained more comprehensively with reference to the non-limiting embodiments that are detailed in the following description. Descriptions of well-known components and processing techniques are omitted so as to not unnecessarily obscure the embodiments herein. The examples used herein are intended merely to facilitate an understanding of the ways in which the embodiments herein may be practiced and to further enable those of skill in the art to practice the embodiments herein. Accordingly, the examples should not be construed as limiting the scope of the embodiments herein.
[00021] Unless otherwise specified, all terms used in disclosing the invention, including technical and scientific terms, have the meaning as commonly understood by one of ordinary skills in the art to which this invention belongs. By means of further guidance, term definitions may be included to better appreciate the teaching of the present invention.
[00022] As used in the description herein, the meaning of “a,” “an,” and “the” includes plural reference unless the context clearly dictates otherwise. Also, as used in the description herein, the meaning of “in” includes “in” and “on” unless the context clearly dictates otherwise.
[00023] As used herein, the terms “comprise”, “comprises”, “comprising”, “include”, “includes”, and “including” are meant to be non- limiting, i.e., other steps and other ingredients which do not affect the end of result can be added. The above terms encompass the terms “consisting of” and “consisting essentially of”.
[00024] The terms “weight percent”, “percent by weight”, “% by weight”, and variations thereof, as used herein, refer to the concentration of a substance as the weight of that substance divided by the total weight of the composition and multiplied by 100. It is understood that, as used here, “percent”, “%”, and the like are intended to be synonymous with “weight percent”, etc.
[00025] The terms ‘pest’ and ‘insect’ are used synonymously and interchangeability throughout the specification. The terms ‘pest’ or ‘insect’ as used herein refers to any insect or small animal that is harmful or damages crops or livestock or otherwise interferes with the wellbeing of human beings such as spreads disease, causes destruction or is otherwise a nuisance. The term ‘pest’ includes but not limited to arthropods such as insects, arachnids, centipedes, mosquitoes, houseflies, drain flies, vespa spp. (hornet), cockroaches, ants, bedbugs, spiders, mites, aphids, thrips, whiteflies, loopers, worms, beetles, leafrollers, moths, weevils including larvae and eggs thereof, and reptiles such as lizards.
[00026] The term ‘mosquito’ or ‘mosquitoes’ as used herein refer to each and every species of mosquitoes reported in literature. It includes both male and female mosquitoes. The term further includes them in their different stages of life cycles such as egg, larva, pupa, and adult.
[00027] The term ‘controlling’ as used herein refer to repelling, killing, preventing, and/or reducing the population of various indoor and outdoor pest(s) and/or insect(s)
[00028] In some embodiments, the numbers expressing quantities of ingredients, properties such as concentration, reaction conditions, and so forth, used to describe and claim certain embodiments of the invention are to be understood as being modified in some instances by the term “about”. Accordingly, in some embodiments, the numerical parameters set forth in the written description are approximations that can vary depending upon the desired properties sought to be obtained by a particular embodiment. In some embodiments, the numerical parameters should be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of some embodiments of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable.
[00029] The recitation of ranges of values herein is merely intended to serve as a shorthand method of referring individually to each separate value falling within the range. Unless otherwise indicated herein, each individual value is incorporated into the specification as if it were individually recited herein.
[00030] The headings and abstract of the invention provided herein are for convenience only and do not interpret the scope or meaning of the embodiments.
[00031] The following discussion provides many example embodiments of the inventive subject matter. Although each embodiment represents a single combination of inventive elements, the inventive subject matter is considered to include all possible combinations of the disclosed elements. Thus, if one embodiment comprises elements A, B, and C, and a second embodiment comprises elements B and D, then the inventive subject matter is also considered to include other remaining combinations of A, B, C, or D, even if not explicitly disclosed.
[00032] The present disclosure relates generally to the field of pesticidal composition. Particularly, the present disclosure provides a pesticide composition for controlling various indoor and outdoor pests.
[00033] The present disclosure is on the premise of a surprising discovery that when Pimenta dioica and Pogostemon cablin are included as part of a pesticide composition in the weight percentages as defined herein, it exhibits exceptional functional reciprocity and synergistic activity, and affords dramatic improvement in controlling the population of various indoor as well as outdoor pests as compared to the individual ingredients and that too at a very low concentration. The observed synergistic effect is unexpected and surprising.
[00034] An aspect of the present disclosure relates to a pesticide composition for controlling indoor and outdoor pests, said composition including: Pimenta dioica in an amount ranging from 1% to 40% by weight of the composition; Pogostemon cablin in an amount ranging from 1% to 40% by weight of the composition; and rest being an excipient.
[00035] In an embodiment, the pesticide composition includes Pimenta dioica in an amount ranging from 1% to 35% by weight, including 2% to 35%, 4% to 35%, 4% to 30%, 5% to 30, 6% to 28%, 6% to 26%, 8% to 24% or 10% to 26%. In an embodiment, the composition comprises Pogostemon cablin in an amount ranging from 1% to 35% by weight, including 2% to 35%, 4% to 35%, 4% to 30%, 5% to 30, 6% to 28%, 6% to 26%, 8% to 24% or 10% to 26%.
[00036] In an embodiment, Pimenta dioica is present in an amount ranging from 1.5% to 35% by weight of the composition; Pogostemon cablin is present in an amount ranging from 1.5% to 35% by weight of the composition; and rest being an excipient.
[00037] In an embodiment, the composition comprises: whole of or a part of or an extract of or an oil of Pimenta dioica. In an embodiment, the composition comprises roots, leaves, shoot, fruits, husk, seed, stem, barks sap or bud, inflorescence or combination thereof of Pimenta dioica. In an embodiment, the composition comprises leaves, stem, fruits, roots, inflorescence or combination thereof of Pimenta dioica. In an embodiment, Pimenta dioica herb is of natural origin grown in natural conditions or a genetically modified variety of Pimenta dioica exhibiting properties such as but not limited to enriched mosquito spatial repellency, indoor acclimatization (can grow and survive in an indoor environment), heights of around 3 feet, and the likes or combination thereof. In an embodiment, Pimenta dioica is a herb produced from techniques such as tissue culturing, or horticultural practices like layering, grafting, stem cutting etc. having attributes like less water requirements and faster growth. In an embodiment, the composition comprises berry oil of Pimenta dioica.
[00038] In an embodiment, the composition comprises: whole of or a part of or an extract of or an oil of Pogostemon cablin. In an embodiment, the composition comprises root, leaves, twigs, flower, seeds or combination thereof of Pogostemon cablin. In an embodiment, the composition comprises leaves or twigs of Pogostemon cablin. In an embodiment, the composition comprises oil of Pogostemon cablin. In an embodiment, the composition comprises leaf oil of Pogostemon cablin.
[00039] In an embodiment, the excipient is selected from any or a combination of a perfume, a preservative, an adhesive, a smoldering agent or a burning aid, a binder, a filler or a burnable base, a propellant, a solvent, a wetting agent, a solubilizer, a hardening agent, an emulsifier, a diluent, a lubricant, a colouring agent, a lower alcohol, and a neutralization base.
[00040] In an embodiment, the perfume(s)/fragrance agent includes but not limited to, various commercially available camphors (karpur) of natural or synthetic origin, orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, citronella oil, lime oil, yuzu oil, jasmine oil, cypress oil, green tea essential oil, limonene, a-pinene, linalool, geraniol, phenylethyl alcohol, amylcinnamic aldehyde, cuminaldehyde, benzyl acetate, Pure Soul MMN37683, Classic Guggul MMN37681, Lemony perfume, and combinations thereof. However, a person skilled in the art would appreciate that any other perfume(s) can be utilized to serve the intended purpose.
[00041] In an embodiment, the preservative(s) includes but not limited to, sodium benzoate, potassium sorbate, phenoxyethanol, p-hydroxybenzoic acid esters, sorbic acid, benzoic acid, propionic acid or salts, Butylated Hydroxytoluene (BHT), and combinations thereof. However, a person skilled in the art would appreciate that any other preservative(s) can be utilized to serve the intended purpose.
[00042] In an embodiment, the adhesive(s) includes but not limited to, Joss (Jiggit powder), corn starch, wheat starch, potato starch, pea starch, Tamarind starch, etc. However, a person skilled in the art would appreciate that any other adhesive(s) can be utilized to serve the intended purpose.
[00043] In an embodiment, the smoldering agent(s) or burning aid(s) includes but not limited to, potassium nitrate (KNO3), sodium nitrate (NaNO3), potassium chloride, and combinations thereof. However, a person skilled in the art would appreciate that any other smoldering agent(s) or burning aid(s) can be utilized to serve the intended purpose.
[00044] In an embodiment, the binder(s) includes but not limited to, guar gum, starch, for example, potato starch, maize starch, corn starch, tamarind seed powder, water, povidone, copovidone, kaolin and combinations thereof. However, a person skilled in the art would appreciate that any other binder(s) can be utilized to serve the intended purpose.
[00045] In an embodiment, the filler(s) or burnable base(s) or a thickener includes but not limited to, Aerosil 200, Paraffin wax, saw dust powder, Joss (Jiggit powder), coconut shell powder, wood powder, wood chips, wood fiber, wood charcoal, vegetable shell powders, for e.g. cocoa shell, peanut shell, fibrous waste, for e.g. rayon waste, cotton waste, waste paper and mineral fibers, and combinations thereof. However, a person skilled in the art would appreciate that any other filler(s) or burnable base(s) can be utilized to serve the intended purpose.
[00046] In an embodiment, the propellant(s) includes but not limited to, liquefied petroleum gas (LPG), dimethyl ether (DME), nitrogen gas, carbonic acid gas, nitrous oxide, compressed air, and combinations thereof. However, a person skilled in the art would appreciate that any other propellant(s) can be utilized to serve the intended purpose.
[00047] In an embodiment, the solvent(s) includes but not limited to, hydrocarbons such as aliphatic hydrocarbon (C5 to C20 carbon atoms having branched and/or unbranched chains), aromatic hydrocarbon and alicyclic hydrocarbon, alcohols such as ethanol, isopropanol and methanol, esters such as fatty acid ester, vegetable oils, animal oils, and water. Further, among the aliphatic hydrocarbons, a paraffinic hydrocarbon (linear or branched saturated hydrocarbon), inter alia, normal paraffin (n-paraffin) is preferably used. It further includes higher fatty acid esters and alcohols. It further includes D-80, D-100 or mixture thereof in required amount. Preferable examples of the organic solvent include higher fatty acid esters and alcohols. The higher fatty acid ester preferably has 16 to 20 carbon atoms in total. Examples of such a higher fatty acid ester include isopropyl myristate, butyl myristate, hexyl laurate, isopropyl palmitate, and combinations thereof. However, a person skilled in the art would appreciate that any other solvent(s) can be utilized to serve the intended purpose.
[00048] In an embodiment, the wetting agent(s) includes but not limited to, 1,2-propylene glycol, glycerol, hyaluronate sodium, and combinations thereof. However, a person skilled in the art would appreciate that any wetting agent(s) can be utilized to serve the intended purpose.
[00049] In an embodiment, solubilizer(s) includes but not limited to, isomeryl alcohol APEO, PEG-40 PEG-60, polysorbas20, the Tween 80, and combinations thereof. However, a person skilled in the art would appreciate that any other solubilizer(s) can be utilized to serve the intended purpose.
[00050] In an embodiment, hardening agent(s) includes but not limited to, water miscible sylvite, sodium salt, magnesium salts, calcium salt, and combinations thereof. However, a person skilled in the art would appreciate that any other hardening agent(s) can be utilized to serve the intended purpose.
[00051] In an embodiment, the emulsifier(s) includes but not limited to, hydrogenated lecithin, C12-16 Alcohols, palmitic acid (e.g., Biophillic™ H) and cetyl alcohol, glyceryl stearate, PEG-75 stearate, ceteth-20, steareth-2 (Emulium® Delta), Tween (Tween 20, Tween 40, Tween 60 and Tween 80) and combinations thereof. However, a person skilled in the art would appreciate that any other emulsifier (s) can be utilized to serve the intended purpose.
[00052] In an embodiment, the diluent(s) includes but not limited to, microfine cellulose, lactose, starch, pregelatinized starch, calcium carbonate, calcium sulphate, sugar, dextrates, dextrin, dextrose, dibasic calcium phosphate dihydrate, tribasic calcium phosphate, kaolin, magnesium carbonate, magnesium oxide, maltodextrin, mannitol, potassium chloride, powdered cellulose, sodium chloride, sorbitol, talc, and combinations thereof. However, a person skilled in the art would appreciate that any other diluent(s) can be utilized to serve the intended purpose.
[00053] In an embodiment, the lubricant(s) includes but not limited to, zinc stearate, magnesium stearate, stearic acid, calcium stearate, Vegetable stearin, and combinations thereof. However, a person skilled in the art would appreciate that any other lubricant(s) can be utilized to serve the intended purpose.
[00054] In an embodiment, the colouring agent(s) includes but not limited to, E102 Tartrazine, E104 Quin- oline Yellow, E110 Sunset Yellow FCF, E120 - Cochineal, carminic acid, Carmines, E122 Azorubine (Carmoisine), E123 Amaranth, E124 Ponceau 4R (Cochineal Red A), E127 Erythrosine, E129 Allura Red, E131 Patent Blue, and combinations thereof. However, a person skilled in the art would appreciate that any other colouring agent(s) can be utilized to serve the intended purpose.
[00055] In an embodiment, lower alcohol(s) includes but not limited to, ethanol, ethylene glycol, propane diols, glycerin, butanediol, and combinations thereof. However, a person skilled in the art would appreciate that any other lower alcohol(s) can be utilized to serve the intended purpose.
[00056] In an embodiment, the neutralization base includes but not limited to, triethanolamine. However, a person skilled in the art would appreciate that any other neutralization base(s) can be utilized to serve the intended purpose.
[00057] While one or more embodiments of the present disclosure enumerates and describes a list of excipients that may be used in the composition to serve an intended purpose, it should be appreciated that one or more excipient(s) may also serve more than one function, obviating the need of inclusion of separate excipients for the specified purpose. Although several embodiments of the present disclosure names few of the commonly used excipients, any other excipient(s) known to or appreciated by a skilled person can also be used to realize the advantageous compositions of the present disclosure.
[00058] The ingredients of the compositions/formulations of the present disclosure exhibit functional reciprocity there between, and accordingly aids in repelling, killing, preventing, and/or reducing the population of indoor as well as outdoor pests. Compositions/formulations of the present disclosure also exhibit superior storage stability. The composition of the present disclosure also provides a pleasant aroma by releasing different fragrances to give an aromatherapy effect while knocking down the harmful pests.
[00059] The composition detailed herein can be manufactured in one or several forms. In an embodiment, form is selected from any or a combination of liquids, semisolids (gels), solids, gels or gases. In an embodiment, the composition of the present disclosure may be formulated into any formulation including but not limited to cream, lotion, ointment, gel, spray, vaporizer, granule, paste, powder, dust, wax, chalk, granules, pellet, burn paper, coils, dhoop sticks, incense stick, a self-ignite product such as a match box, a stick, a cracker, candles, etc., pellets, bait, cordages, candles, cones, sealing agent, caulk, chalk, patch, bait, mats, detergent, filler, wood filler, crack and cervice filler, dry wall mixture, fabric composition, liquid vaporizers, aerosols, emulsion, suspension, micro-emulsion, varnish dispersions, fumigant, solution and the likes. In an embodiment, above pesticidal compositions can be developed in non-smoldering form for protection from pests.
[00060] In an embodiment, the composition is formulated into a cream, a lotion, an ointment, a gel, a spray, a vaporizer, a paste, a powder, a dust, a wax, a chalk, granules, pellets, a burn paper, a coil, an incense stick, pellets, a bait, cordages, a candle, a sealing agent, a caulk, a patch, a bait, a mat, a filler, a wood filler, a self-ignite formulation, a mist, a liquid vaporizer, an aerosol, an emulsion, a suspension, a micro-emulsion, a varnish dispersion, a fumigant, or a solution.
[00061] In an embodiment, the composition is formulated into a liquid form, a semi-solid form, a solid form, a gel or a gaseous form.
[00062] However, composition of the present formulation may be formulated into any or a combination of other pesticide formulation(s), as known to or appreciated by a person skilled in the art to serve the intended purpose. In an embodiment, the composition of the present disclosure can be manufactured by any conventional method, known to or appreciated by a person skilled in the art working in the pertinent field to serve the intended purpose.
[00063] Another aspect of the present disclosure relates to a liquid or a semisolid pesticide formulation for controlling indoor and outdoor pests, said formulation including: Pimenta dioica in an amount ranging from 1% to 40% by weight of the formulation; Pogostemon cablin in an amount ranging from 1% to 40% by weight of the formulation; and rest being an excipient. In an embodiment, the liquid or a semisolid formulation includes a cream, a lotion, an ointment, a gel, a spray, a vaporizer, a paste, a mist, a liquid vaporizer, an aerosol, an emulsion, a suspension, a micro-emulsion, a varnish dispersion, a fumigant, or a solution.
[00064] Still another aspect of the present disclosure relates to a solid pesticide formulation for controlling indoor and outdoor pests, said formulation including: Pimenta dioica in an amount ranging from 1% to 40% by weight of the formulation; Pogostemon cablin in an amount ranging from 1% to 40% by weight of the formulation; and rest being an excipient. In an embodiment, the solid formulation includes a granule, a paste, a powder, a dust, a wax, a chalk, pellets, a burn paper, a coil, an incense stick, pellets, a bait, cordages, a candle, a sealing agent, a caulk, a patch, a bait, a mat, a filler, a wood filler, a self-ignite formulation, or a vaporizer.
[00065] Pimenta dioica or Pimenta dioica (L.) Merr. (Allspice) also known as Jamaican pepper or pimento, a tropical evergreen tree of the myrtle family (Myrtaceae). The plant is native to the West Indies, Central America and cultivated in many parts of India. Allspice is so named because the flavour of the dried berry resembles a combination of cloves, cinnamon, and nutmeg. Its berries are the source of a highly aromatic spice.
[00066] Pogostemon cablin is a species of flowering plant in the family Lamiaceae, commonly called the mint or deadnettle family. The plant grows as a bushy perennial herb, with erect stems reaching up to 75 centimetres (2.5 ft) in height and bearing small, pale pink-white flowers. It is commonly known as Patchouli. It is native to the island region of Southeast Asia, including Sri Lanka, Indonesia, and the Philippines. It is also found in many parts of North East India.
[00067] In accordance with an embodiment, the composition of the present disclosure is realized by using extracts or oils or any plant part thereof commercially procured from following manufactures:

Sr. No. INGREDIENTS MANUFACTURER
1 Pimenta dioica
(Common name: Allspice) Katyani Exports, New Delhi, India.
2 Pogostemon cablin
(Common name: Patchouli) Jl. Raya Wanaherang No.16, RT.4/RW.4, Cicadas, Kec. Gn. Putri, Kabupaten Bogor, Jawa Barat 16964, Indonesia

[00068] In an embodiment, the compositions and formulations of the present disclosure can be manufactured by any conventional method, known to or appreciated by a person skilled in the art working in the pertinent field to serve the intended purpose.
[00069] The ingredients of the composition of the present disclosure exhibit functional reciprocity there between, and accordingly aids in repelling, killing, preventing, and/or reducing the population of indoor as well as outdoor pests. Compositions/formulations of the present disclosure also exhibit superior storage stability. The composition of the present disclosure also provides a pleasant aroma by releasing different fragrances to give an aromatherapy effect while knocking down the harmful pests. The composition is safe and free of ill-effects such as irritation, allergy, uneasiness, reduction in oxygen content etc.
EXAMPLES
[00070] EXAMPLE 1
[00071] AN AEROSOL FORMULATION OF PIMENTA DIOICA
TABLE 1: An Aerosol formulation of Pimenta dioica
Sr. No. Ingredients Role in formulation Amount in wt. %
1 Pimenta dioica
(essential oil) Pesticide 15
2 Butylated Hydroxytoluene (BHT) Preservative 1
3 Lemony Perfume Fragrance 2
4 LPG Propellant 82
Total 100

[00072] All the ingredients were weighed accurately as per Table 1 above and were properly mixed (except propellant) to obtain a blend in a beaker. The blend was transferred in a commercially available aerosol tin, and a valve is put in the tin followed by its crimping to obtain a crimped tin. Above weight propellant was added into the crimped tin to obtain the aerosol formulation of Pimenta dioica and was used for controlling various indoor and outdoor pests.
[00073] AN AEROSOL FORMULATION OF POGOSTEMON CABLIN
TABLE 2: An Aerosol formulation of Pogostemon cablin
Sr. No. Ingredients Role in formulation Amount in wt. %
1 Pogostemon cablin
(leaf essential oil) Pesticide 15
2 Butylated Hydroxytoluene (BHT) Preservative 1
3 Lemony Perfume Fragrance 2
4 LPG Propellant 82
Total 100

[00074] All the ingredients were weighed accurately as per Table 2 above and were properly mixed (except propellant) to obtain a blend in a beaker. The blend was transferred in a commercially available aerosol tin, and a valve is put in the tin followed by its crimping to obtain a crimped tin. Above weight propellant was added into the crimped tin to obtain the aerosol formulation of Pogostemon cablin and was used for controlling various indoor and outdoor pests.
[00075] AN AEROSOL FORMULATION OF PIMENTA DIOICA AND POGOSTEMON CABLIN

TABLE 3: An Aerosol formulation of Pimenta dioica and Pogostemon cablin
Sr. No. Ingredients Role in formulation Formulation 1 Formulation 2 Formulation 3
(amount in wt. %)
1 Pimenta dioica
(berry essential oil) Pesticide 2 4 8
2 Pogostemon cablin
(leaf essential oil) Pesticide 2 4 8
3 Butylated Hydroxytoluene (BHT) Preservative 1 1 1
4 Lemony Perfume Fragrance 2 2 2
5 LPG Propellant 93 89 81
Total 100 100 100

[00076] All the ingredients were weighed accurately as per Table 3 above and were properly mixed (except propellant) to obtain a blend in a beaker. The blend was transferred into a commercially available aerosol tin, and a valve is put in the tin followed by its crimping to obtain a crimped tin. Above weight propellant was added into the crimped tin to obtain the aerosol formulation of present disclosure comprising Pimenta dioica and Pogostemon cablin oil and was used for controlling various indoor and outdoor pests.
[00077] EFFICACY STUDY - SYNERGISTIC ACTIVITY OF THE AEROSOL FORMULATION
[00078] The aerosol Formulation 1 realized in Table 3 above vis-à-vis the aerosol formulations of the individual active ingredient(s) (Pimenta dioica and Pogostemon cablin, patchouli oil) prepared in Table 1 and Table 2 were subjected to efficacy studies, particularly, mosquitocidal activity. The mosquitocidal activity was determined by using a Peet Grady Chamber. The Peet Grady Chamber is a 5.8 m3 chamber having all 5 sides made up of glass with glazy tile flooring. At the bottom left side, there is a small window of 0.5 X 0.5 ft. for releasing insects in the chamber. Apart from this, it has a door on one wall and four 2-inch diameter holes on each wall placed at a distance of 1.4 m from the ground and in the centre of the wall. These holes are used for dispensing test products inside the chamber. During experimentation, the holes, door, and small window, all were in closed condition. For consistency and reproducibility of results, the environmental conditions viz. temperature of 27±3°C and Relative Humidity of about 50-80% were maintained. Before evaluating the mosquitocidal activity of Formulation 1 vis-à-vis aerosol formulation of the individual active ingredients, the Culex quinquefasciatus mosquitoes were first introduced into the chamber, and de-contamination checks were performed for the first ½ hour. If no knockdown of mosquito(es) was seen, then a fresh lot (100 nos.) of Culex quinquefasciatus mosquitoes was introduced, and about 2g of Formulation 1, aerosol formulation of the individual active ingredients and a commercially available mosquitocidal aerosol formulation were released in the chamber by spraying, and the experiment was started. The knockdown of insects was observed every 5 minutes for about 60 minutes. Thereafter, the knocked-down mosquitoes were transferred to a clean container with food of 10% sucrose contained in a cotton swab. The mortality readings were noted after 24 hours. Observations were interpreted in Knock-down times, KT50 and KT90 [KT50 is the time (in minutes) needed to knock down 50% of the mosquito population used for an experiment, and KT90 is the time (in minutes) needed to knock down 90% of the mosquito population used for an experiment] and it is determined by the Probit analysis software. Percent mortality was calculated after 24 hours.
Table 4: Comparison of the mosquitocidal activity of aerosol Formulation 1 vis-à-vis aerosol formulations of the individual active ingredient(s)
Sr. No. Item KT50
(in minutes) KT90
(in minutes)
1 15% aerosol formulation of Pimenta dioica
(prepared in Table 1 above) 23 44
2 15% aerosol formulation of Pogostemon cablin
(prepared in Table 2 above) 18 37
3 Formulation 1
(Pimenta dioica (2%) + Pogostemon cablin (2%)
(prepared in Table 3 above) 11 31
4 Commercially available aerosol formulation
(0.25% EBT Aerosol) 10.04 33.12
[00079] As can be seen in Table 4 above, the formulation (formulation 1) of the present disclosure affords improved control of mosquitoes (pests) as compared to the formulations of the individual active ingredients and that too at a very low concentration of each pesticide agent. Accordingly, it could be concluded that the composition/ formulation of the present disclosure, exhibits a synergistic effect (functional reciprocity) and offers significant improvement in controlling various indoor and outdoor pests as compared to the compositions/ formulations of the individual active ingredient(s).
[00080] EXAMPLE 2: A MIST FORMULATION OF PIMENTA DIOICA AND POGOSTEMON CABLIN AND SYNERGISTIC ACTIVITY THEREOF
TABLE 5: A Mist formulation of Pimenta dioica and Pogostemon cablin and synergistic activity thereof
BIO-EFFICACY Sr. No. Ingredients Role in formulation Formulation A
(wt. %) Formulation B
(wt. %) Formulation C
(wt. %)
1 Pimenta dioica (Berry essential oil) Pesticidal 15 -- 7.5
2 Pogostemon cablin (Leaf essential oil) Pesticidal -- 15 7.5
3 Tween 20 Emulsifier 30 30 30
4 Lemony Perfume Fragrance 2 2 2
5 Water Solvent 53 53 53

MOSQUITOCIDAL ACTIVITY KT50 (Min) 6 7 3
KT90 (Min) 12 19 10

[00081] The Mist Formulation C realized in Table 5 above vis-à-vis the mist formulations (Formulations A and B) of the individual active ingredient(s), (Pimenta dioica and Pogostemon cablin) were subjected to efficacy studies, particularly, mosquitocidal activity as above.
As can be seen in Table 5 above, the Formulation C of the present disclosure affords improved control of mosquitoes (pests) as compared to the formulations of the individual active ingredients (Formulations A and B) and that too at a very low concentration of each pesticide agent. Accordingly, it could be concluded that the composition/ formulation of the present disclosure, exhibits a synergistic effect (functional reciprocity) and offers significant improvement in controlling various indoor and outdoor pests as compared to the compositions/ formulations of the individual active ingredient(s).
[00082] EXAMPLE 3: A LIQUID VAPORIZER FORMULATION OF PIMENTA DIOICA AND POGOSTEMON CABLIN AND SYNERGISTIC ACTIVITY THEREOF
TABLE 6: A Liquid vaporizer formulation of Pimenta dioica and Pogostemon cablin and synergistic activity thereof
BIO-EFFICACY Sr. No. Ingredients Role in formulation Formulation A
(wt. %) Formulation B
(wt. %) Formulation C
(wt. %)
1 Pimenta dioica (Berry essential oil) Pesticidal 24 -- 12
2 Pogostemon cablin (Leaf essential oil) Pesticidal -- 24 12
3 D-80 Solvent 52.5 52.5 52.5
4 D-100 Solvent 22.5 22.5 22.5
5 BHT Preservative 1 1 1

MOSQUITOCIDAL ACTIVITY KT50 (Min) 21 14 11

[00083] As can be seen in Table 6 above, the Formulation C of the present disclosure affords improved control of mosquitoes (pests) as compared to the formulations of the individual active ingredients (Formulations A and B) and that too at a very low concentration of each pesticide agent. Accordingly, it could be concluded that the composition/ formulation of the present disclosure, exhibits a synergistic effect (functional reciprocity) and offers significant improvement in controlling various indoor and outdoor pests as compared to the compositions/ formulations of the individual active ingredient(s).
[00084] EXAMPLE 4: A CANDLE FORMULATION OF PIMENTA DIOICA AND POGOSTEMON CABLIN
TABLE 7: A Candle formulation of Pimenta dioica and Pogostemon cablin
Sr. No. Ingredients Role in formulation Formulation A1
(wt. %) Formulation A2
(wt. %) Formulation A3
(wt. %)
1 Pimenta dioica (Berry essential oil) Pesticidal 3 5.35 10
2 Pogostemon cablin (Leaf essential oil) Pesticidal 3 5.35 10
3 Paraffin wax Filler 94 89.3 80
TOTAL 100

[00085] EXAMPLE 5: A GEL FORMULATION OF PIMENTA DIOICA AND POGOSTEMON CABLIN
TABLE 8: A gel formulation of Pimenta dioica and Pogostemon cablin
Sr. No. Ingredients Role in formulation Formulation A1
(wt. %) Formulation A2
(wt. %) Formulation A3
(wt. %)
1 Pimenta dioica (Berry essential oil) Pesticidal 7.5 10 12.5
2 Pogostemon cablin (Leaf essential oil) Pesticidal 7.5 10 12.5
3 Aerosil 200 Thickener 8 8 8
4 Tween 20 Emulsifier 77 72 67
TOTAL 100

[00086] The foregoing description of the specific embodiments will so fully reveal the general nature of the embodiments herein that others can, by applying current knowledge, readily modify and/or adapt for various applications such specific embodiments without departing from the generic concept, and, therefore, such adaptations and modifications should and are intended to be comprehended within the meaning and range of equivalents of the disclosed embodiments. It is to be understood that the phraseology or terminology employed herein is for the purpose of description and not of limitation. Therefore, while the embodiments herein have been described in terms of preferred embodiments, those skilled in the art will recognize that the embodiments herein can be practiced with modification within the spirit and scope of the embodiments as described herein.

ADVANTAGES
[00087] The present disclosure provides a pesticide composition/formulation that overcomes the limitations associated with the conventional compositions/formulations.
[00088] The present disclosure provides a pesticide composition/formulation for repelling and/or reducing and/or controlling various indoor and outdoor pests.
[00089] The present disclosure provides a pesticide composition/formulation for repelling and/or reducing and/or controlling the population of mosquitoes.
[00090] The present disclosure provides a pesticide composition/formulation that exhibits high repellence and pesticidal activity.
[00091] The present disclosure provides a pesticide composition/formulation that is safe and free of side-effects such as irritation, allergy, uneasiness, reduction in oxygen content, etc.
[00092] The present disclosure provides a pesticide composition/formulation that exhibits synergistic activity /functional reciprocity, economical and easy to prepare.
, Claims:1. A pesticide composition for controlling indoor and outdoor pests, said composition comprising:
Pimenta dioica in an amount ranging from 1% to 40% by weight of the composition;
Pogostemon cablin in an amount ranging from 1% to 40% by weight of the composition; and
rest being an excipient.
2. The Composition as claimed in claim 1, wherein Pimenta dioica is present in an amount ranging from 1.5% to 35% by weight of the composition; Pogostemon cablin is present in an amount ranging from 1.5% to 35% by weight of the composition; and rest being an excipient.
3. The Composition as claimed in claim 1, wherein the excipient is selected from any or a combination of a perfume, a preservative, an adhesive, a smoldering agent, a burning aid, a binder, a filler, a burnable base, a propellant, a solvent, a wetting agent, a solubilizer, a hardening agent, an emulsifier, a diluent, a lubricant, a colouring agent, a lower alcohol, and a neutralization base.
4. The Composition as claimed in claim 1, wherein the composition is formulated into a liquid form, a semi-solid form, a solid form, a gel or a gaseous form.
5. The Composition as claimed in claim 1, wherein the composition is formulated into a cream, a lotion, an ointment, a gel, a spray, a vaporizer, a paste, a powder, a dust, a wax, a chalk, granules, pellets, a burn paper, a coil, an incense stick, pellets, a bait, cordages, a candle, a sealing agent, a caulk, a patch, a bait, a mat, a filler, a wood filler, a self-ignite formulation, a mist, a liquid vaporizer, an aerosol, an emulsion, a suspension, a micro-emulsion, a varnish dispersion, a fumigant, or a solution.
6. A liquid or a semisolid pesticide formulation for controlling indoor and outdoor pests, said formulation comprising:
Pimenta dioica in an amount ranging from 1% to 40% by weight of the formulation;
Pogostemon cablin in an amount ranging from 1% to 40% by weight of the formulation; and
rest being an excipient.
7. The liquid or a semisolid formulation as claimed in claim 1, wherein the liquid or a semisolid formulation comprises a cream, a lotion, an ointment, a gel, a spray, a vaporizer, a paste, a mist, a liquid vaporizer, an aerosol, an emulsion, a suspension, a micro-emulsion, a varnish dispersion, a fumigant, or a solution.
8. A solid pesticide formulation for controlling indoor and outdoor pests, said formulation comprising:
Pimenta dioica in an amount ranging from 1% to 40% by weight of the formulation;
Pogostemon cablin in an amount ranging from 1% to 40% by weight of the formulation; and
rest being an excipient.
9. The solid formulation as claimed in claim 1, wherein the solid formulation comprises a granule, a paste, a powder, a dust, a wax, a chalk, pellets, a burn paper, a coil, an incense stick, pellets, a bait, cordages, a candle, a sealing agent, a caulk, a patch, a bait, a mat, a filler, a wood filler, a self-ignite formulation, or a vaporizer.