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Pharmaceutical Composition Of A Cyp11 A1 Inhibitor

Abstract: The present invention relates to a pharmaceutical composition for oral administration, particularly in the form of a tablet or a powder suitable to be filled into a capsule shell, comprising 2-(isoindolin-2-ylmethyl)-5-((1-(methylsulfonyl)-piperidin-4-yl)methoxy)-4H-pyran-4-one (I) or a pharmaceutically acceptable salt thereof as an active ingredient. Compound (I) or a pharmaceutically acceptable salt thereof is a selective inhibitor of CYP11A1 enzyme and is useful in the treatment of hormonally regulated diseases such as cancer including prostate cancer and breast cancer.

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Patent Information

Application #
Filing Date
09 July 2024
Publication Number
51/2024
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
Parent Application

Applicants

ORION CORPORATION
Orionintie 1 02200 Espoo

Inventors

1. SALMIA, Jukka
Forsellesintie 18 A 3 02700 Kauniainen
2. SINGHAL, Mayank
2 Cornfield Close MacClesfield SK10 2TY
3. TURUNEN, Elina
c/o Orion Corporation P.O.Box 65 02101 Espoo

Specification

Documents

Application Documents

# Name Date
1 202417052580-STATEMENT OF UNDERTAKING (FORM 3) [09-07-2024(online)].pdf 2024-07-09
2 202417052580-REQUEST FOR EXAMINATION (FORM-18) [09-07-2024(online)].pdf 2024-07-09
3 202417052580-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [09-07-2024(online)].pdf 2024-07-09
4 202417052580-FORM 18 [09-07-2024(online)].pdf 2024-07-09
5 202417052580-FORM 1 [09-07-2024(online)].pdf 2024-07-09
6 202417052580-DECLARATION OF INVENTORSHIP (FORM 5) [09-07-2024(online)].pdf 2024-07-09
7 202417052580-COMPLETE SPECIFICATION [09-07-2024(online)].pdf 2024-07-09
8 202417052580-Proof of Right [18-07-2024(online)].pdf 2024-07-18
9 202417052580-FORM-26 [23-08-2024(online)].pdf 2024-08-23
10 202417052580-FORM 3 [02-01-2025(online)].pdf 2025-01-02
11 202417052580-MARKED COPIES OF AMENDEMENTS [24-10-2025(online)].pdf 2025-10-24
12 202417052580-FORM 13 [24-10-2025(online)].pdf 2025-10-24
13 202417052580-AMMENDED DOCUMENTS [24-10-2025(online)].pdf 2025-10-24