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Oligonucleotide Compositions And Methods Thereof For Exon Skipping

Abstract: Among other things, the present disclosure provides various technologies including chirally controlled oligonucleotide compositions and technologies for manufacturing and using such oligonucleotide compositions. In some embodiments, the present disclosure provides technologies useful for preventing or treating various conditions, disorders or diseases, e.g., Duchenne Muscular Dystrophy.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
04 September 2024
Publication Number
2/2025
Publication Type
INA
Invention Field
BIO-CHEMISTRY
Status
Email
Parent Application

Applicants

WAVE LIFE SCIENCES LTD.
7 Straits View #12-00 Marina One East Tower Singapore 018936

Inventors

1. HU, Xiao Shelley
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
2. LAKE, Stephen Lister
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
3. PANZARA, Michael Angelo
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
4. LAMORE, Sarah Diane
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
5. HART, Andrew Harrison
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
6. XU, Danlin
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
7. BOWMAN, Keith Andrew
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
8. SHIMIZU, Mamoru
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
9. ADUDA, Vincent
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
10. ALAM, Mohammed Rowshon
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
11. ROSS, Philip
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
12. GAO, Jianxin
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138
13. ZHANG, Yilin
c/o WAVE LIFE SCIENCES LTD. 733 Concord Avenue Cambridge, Massachusetts 02138

Specification

Documents

Application Documents

# Name Date
1 202417066992-STATEMENT OF UNDERTAKING (FORM 3) [04-09-2024(online)].pdf 2024-09-04
2 202417066992-REQUEST FOR EXAMINATION (FORM-18) [04-09-2024(online)].pdf 2024-09-04
3 202417066992-POWER OF AUTHORITY [04-09-2024(online)].pdf 2024-09-04
4 202417066992-NOTIFICATION OF INT. APPLN. NO. & FILING DATE (PCT-RO-105-PCT Pamphlet) [04-09-2024(online)].pdf 2024-09-04
5 202417066992-FORM 18 [04-09-2024(online)].pdf 2024-09-04
6 202417066992-FORM 1 [04-09-2024(online)].pdf 2024-09-04
7 202417066992-DRAWINGS [04-09-2024(online)].pdf 2024-09-04
8 202417066992-DECLARATION OF INVENTORSHIP (FORM 5) [04-09-2024(online)].pdf 2024-09-04
9 202417066992-COMPLETE SPECIFICATION [04-09-2024(online)].pdf 2024-09-04
10 202417066992-Proof of Right [20-09-2024(online)].pdf 2024-09-20
11 202417066992-FORM 3 [19-02-2025(online)].pdf 2025-02-19