Ceacam5 Antibody Drug Conjugates And Methods Of Use Thereof

Abstract: The present invention relates to antibody-drug conjugates comprising an antibody that binds to CEACAM5 conjugated to a drug, such as a Topoisomerase I inhibitor. Also provided herein are methods of treating cancer comprising administering such ADCs.

Patent Information

Application #

Filing Date

21 May 2025

Publication Number

36/2025

Publication Type

INA

Invention Field

BIOTECHNOLOGY

Status

Email

Parent Application

Applicants

SANOFI

46 avenue de la Grande Armée 75017 Paris

SEAGEN INC.

21823 30th Drive S.E. Bothell, Washington 98021

Inventors

1. BAUDAT, Yves

c/o Sanofi Patent Department 46 avenue de la Grande Armée 75017 Paris

2. BRUN, Marie-Priscille

c/o Sanofi Patent Department 46 avenue de la Grande Armée 75017 Paris

3. DÉCARY, Stéphanie

c/o Sanofi Patent Department 46 avenue de la Grande Armée 75017 Paris

4. JEFFREY, Scott

c/o Seagen Inc. 21823 30th Drive S.E. Bothell, Washington 98021

5. LYSKI, Ryan

c/o Seagen Inc. 21823 30th Drive S.E. Bothell, Washington 98021

6. NICOLAZZI, Céline

c/o Sanofi Patent Department 46 avenue de la Grande Armée 75017 Paris

Specification

Documents

Application Documents

#	Name	Date
1	202517049157-TRANSLATIOIN OF PRIOIRTY DOCUMENTS ETC. [21-05-2025(online)].pdf	2025-05-21
2	202517049157-STATEMENT OF UNDERTAKING (FORM 3) [21-05-2025(online)].pdf	2025-05-21
4	202517049157-Sequence Listing in PDF [21-05-2025(online)].pdf	2025-05-21
5	202517049157-REQUEST FOR EXAMINATION (FORM-18) [21-05-2025(online)].pdf	2025-05-21
6	202517049157-FORM 18 [21-05-2025(online)].pdf	2025-05-21
7	202517049157-FORM 1 [21-05-2025(online)].pdf	2025-05-21
8	202517049157-DRAWINGS [21-05-2025(online)].pdf	2025-05-21
9	202517049157-DECLARATION OF INVENTORSHIP (FORM 5) [21-05-2025(online)].pdf	2025-05-21
10	202517049157-COMPLETE SPECIFICATION [21-05-2025(online)].pdf	2025-05-21
11	202517049157-Proof of Right [18-08-2025(online)].pdf	2025-08-18
12	202517049157-FORM-26 [18-08-2025(online)].pdf	2025-08-18
13	202517049157-FORM 3 [31-10-2025(online)].pdf	2025-10-31