Abstract: The present disclosure relates to a composition comprising Theobroma Cocoa extract, and Andrographis paniculata extract, and uses thereof. The disclosure also provides for a method of use of the said composition for neuro-protection and inhibiting neuronal toxicity.
Claims:1. A composition for comprising:
a) Theobroma cocoa extract; and
b) Andrographis paniculata extract,
wherein Theobroma cocoa extract to Andrographis paniculata extract w/w ratio in said composition is in the range of 1:1.5-1:9.
2. The composition as claimed in claim 1, wherein Theobroma cocoa extract to Andrographis paniculata extract w/w ratio in said composition is in the range of 1:1.5-1:4.
3. The composition as claimed in claim 1, wherein Theobroma cocoa extract weight concentration in said composition is in the range of 0.3125-1.25µg/ml, and Andrographis paniculata extract weight concentration in said composition is in the range of 1.875-2.8125µg/ml.
4. The composition as claimed in claim 2, wherein Theobroma cocoa extract weight concentration in said composition is in the range of 0.625-1.25µg/ml, and Andrographis paniculata extract weight concentration in said composition is in the range of 1.875-2.5µg/ml.
5. The composition as claimed in any of the claims 1-4, further comprising at least one carrier, diluent, and excipient.
6. A method of preparing a composition as claimed in any of the claims 1-5.
7. A method for inhibiting neuronal toxicity, said method comprising the steps:
a. obtaining a composition as claimed in any of the claims 1-5; and
b. contacting said composition with neurons,
wherein said method inhibits neuronal toxicity.
8. The method as claimed in claim 7, wherein neuronal toxicity is chemically induced.
9. A composition as claimed in any of the claims 1-5, for use in preparation of formulations for inhibiting neuronal cytotoxicity.
, Description:N/A
| # | Name | Date |
|---|---|---|
| 1 | Form 5 [21-03-2016(online)].pdf | 2016-03-21 |
| 2 | Form 3 [21-03-2016(online)].pdf | 2016-03-21 |
| 3 | Drawing [21-03-2016(online)].pdf | 2016-03-21 |
| 4 | Description(Complete) [21-03-2016(online)].pdf | 2016-03-21 |
| 5 | 201641009857-Power of Attorney-030516.pdf | 2016-07-15 |
| 6 | 201641009857-Correspondence-PA-030516.pdf | 2016-07-15 |
| 7 | 201641009857-FORM 18 [20-03-2020(online)].pdf | 2020-03-20 |
| 8 | 201641009857-FER.pdf | 2022-08-26 |
| 9 | 201641009857-OTHERS [24-02-2023(online)].pdf | 2023-02-24 |
| 10 | 201641009857-MARKED COPIES OF AMENDEMENTS [24-02-2023(online)].pdf | 2023-02-24 |
| 11 | 201641009857-FORM 13 [24-02-2023(online)].pdf | 2023-02-24 |
| 12 | 201641009857-FER_SER_REPLY [24-02-2023(online)].pdf | 2023-02-24 |
| 13 | 201641009857-COMPLETE SPECIFICATION [24-02-2023(online)].pdf | 2023-02-24 |
| 14 | 201641009857-CLAIMS [24-02-2023(online)].pdf | 2023-02-24 |
| 15 | 201641009857-AMMENDED DOCUMENTS [24-02-2023(online)].pdf | 2023-02-24 |
| 16 | 201641009857-ABSTRACT [24-02-2023(online)].pdf | 2023-02-24 |
| 1 | TKDLsearchE_25-08-2022.pdf |
| 2 | SearchHistoryE_25-08-2022.pdf |