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A Composition Comprising Apple Leaf Callus Extract, And Nicotinamide And Uses Thereof

Abstract: The present disclosure provides a skin care composition comprising apple leaf callus extract, and nicotinamide, which at particular w/w ratios enhances collagen secretion, which is a marker for healthy and firm skin.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
30 March 2016
Publication Number
49/2017
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
lsmds@lakshmisri.com
Parent Application
Patent Number
Legal Status
Grant Date
2023-06-28
Renewal Date

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3. 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Inventors

1. GOURI, Sree
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
2. KUMARI, Deva
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
3. THALIYAKULA, Suribabu
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
4. BUTTI, Srinu
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
5. SHANKARANARAYANA, Gurumurthy Demlapura
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
6. DIXIT, Ajay Kumar
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
7. CHANDRASEKHARAN, Lakshmanan Chittur
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
8. BANDYOPADHYAY, Balaji
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India

Specification

Claims:1. A composition comprising:
a. apple leaf callus extract; and
b. nicotinamide,
wherein apple leaf callus extract to nicotinamide w/w ratio in said composition is in the range of 1:0.14-1:1.33.
2. The composition as claimed in claim 1, wherein apple leaf callus extract weight percentage in said composition is in the range of 0.003-0.007%, and nicotinamide weight percentage in said composition is in the range of 0.001-0.004%.
3. The composition as claimed in claim 1, wherein apple leaf callus extract to nicotinamide w/w ratio in said composition is 1:0.5.
4. The composition as claimed in claim 3, wherein apple leaf callus extract weight percentage in said composition is 0.005%, and nicotinamide weight percentage in said composition is 0.0025%.
5. The composition as claimed in any of the claims 1-4, further comprising suitable carriers, diluents, and excipients.
6. The composition as claimed in any of the claims 1-4, wherein said apple leaf callus extract is prepared by:
a. obtaining callus mass developed from apple leaf explants;
b. processing said callus mass into a paste and contacting said paste with at least one preservative at a weight concentration in the range of 0.2-0.4%, and at least one anti-oxidant at a weight concentration in the range of 0.1-0.3% to obtain a second paste;
c. contacting said second paste with methanol for 10-15 hours and constant stirring, followed by filtration to obtain a retentate;
d. contacting said retentate with dichloromethane for 10-15 hours and constant stirring, followed by filtration to obtain a filtrate; and
e. drying said filtrate to obtain said apple leaf callus extract.
7. A method of preparing a composition as claimed in any of the claims 1-6.
8. A method of inhibiting appearance of skin aging, said method comprising:
a. obtaining a composition as claimed in any of the claims 1-6; and
b. contacting said composition with skin,
wherein said method inhibits appearance of skin aging.
9. A composition as claimed in any of the claims 1-6 for use in preparing topical formulations to inhibiting appearance of skin aging.
, Description:As Attached

Documents

Application Documents

# Name Date
1 Form 5 [30-03-2016(online)].pdf 2016-03-30
2 Form 3 [30-03-2016(online)].pdf 2016-03-30
3 Drawing [30-03-2016(online)].pdf 2016-03-30
4 Description(Complete) [30-03-2016(online)].pdf 2016-03-30
5 Other Patent Document [20-05-2016(online)].pdf 2016-05-20
6 Form 26 [20-05-2016(online)].pdf 2016-05-20
7 Other Patent Document [22-06-2016(online)].pdf 2016-06-22
8 Form 26 [22-06-2016(online)].pdf 2016-06-22
9 201641011207-Power of Attorney-270616.pdf 2016-07-29
10 201641011207-Form 1-270616.pdf 2016-07-29
11 201641011207-Correspondence-PA-270616.pdf 2016-07-29
12 201641011207-FORM 18 [27-03-2020(online)].pdf 2020-03-27
13 201641011207-FER.pdf 2021-10-17
14 201641011207-FER_SER_REPLY [07-02-2022(online)].pdf 2022-02-07
15 201641011207-US(14)-HearingNotice-(HearingDate-24-06-2022).pdf 2022-05-20
16 201641011207-Correspondence to notify the Controller [22-06-2022(online)].pdf 2022-06-22
17 201641011207-Written submissions and relevant documents [08-07-2022(online)].pdf 2022-07-08
18 201641011207-US(14)-HearingNotice-(HearingDate-15-06-2023).pdf 2023-05-23
19 201641011207-Correspondence to notify the Controller [09-06-2023(online)].pdf 2023-06-09
20 201641011207-FORM-26 [13-06-2023(online)].pdf 2023-06-13
21 201641011207-Written submissions and relevant documents [27-06-2023(online)].pdf 2023-06-27
22 201641011207-PatentCertificate28-06-2023.pdf 2023-06-28
23 201641011207-IntimationOfGrant28-06-2023.pdf 2023-06-28

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