Abstract: The present disclosure relates to combination of hesperitin, and apigenin, which in particular w/w ratio range inhibits of DPP7 protein. DPP7 plays a role in retarding the growth of hair follicles, hence inhibiting DPP7 may provide for stimulating hair growth.
Claims:1. A composition comprising:
(a) hesperitin; and
(b) apigenin,
wherein hesperitin to apigenin w/w ratio in said composition is in the range of 1:1-9:1.
2. The composition as claimed in claim 1, wherein hesperitin concentration in said composition in the range of 0.00025-0.00045%, and apigenin concentration in said composition in the range of 0.00005-0.00025
%.
3. The composition as claimed in claim 1, wherein hesperitin to apigenin w/w ratio in said composition is 4:1.
4. The composition as claimed in claim 3, wherein hesperitin concentration in said composition is 0.0004%, and apigenin concentration in said composition is 0.0001%.
5. The composition as claimed in claim 1, wherein hesperitin to apigenin w/w ratio in said composition is 1.5:1.
6. The composition as claimed in claim 5, wherein hesperitin concentration in said composition is 0.0003%, and apigenin concentration in said composition is 0.0002%.
7. The composition as claimed in any of the claims 1-6, further comprising suitable diluents, excipients, and carriers.
8. A method to prepare a composition as claimed in any of the claims 1-7.
9. A method to promote hair growth, said method comprising:
(a) obtaining a composition as claimed in any of the claims 1-7; and
(b) contacting said composition with hair follicles,
wherein said method promotes hair growth.
10. A composition as claimed in any of the claims 1-7 for use in preparing topical formulations to promote hair growth.
, Description:As Attached
| # | Name | Date |
|---|---|---|
| 1 | Sequence listing [31-03-2016(online)].pdf | 2016-03-31 |
| 2 | Form 5 [31-03-2016(online)].pdf | 2016-03-31 |
| 3 | Form 3 [31-03-2016(online)].pdf | 2016-03-31 |
| 4 | Drawing [31-03-2016(online)].pdf | 2016-03-31 |
| 5 | Description(Complete) [31-03-2016(online)].pdf | 2016-03-31 |
| 6 | Other Patent Document [26-05-2016(online)].pdf | 2016-05-26 |
| 7 | Form 26 [26-05-2016(online)].pdf | 2016-05-26 |
| 8 | 201641011533-Power of Attorney-300516.pdf | 2016-07-22 |
| 9 | 201641011533-Form 1-300516.pdf | 2016-07-22 |
| 10 | 201641011533-Correspondence-F1-PA-300516.pdf | 2016-07-22 |
| 11 | 201641011533-FORM 18 [27-03-2020(online)].pdf | 2020-03-27 |
| 12 | 201641011533-FER.pdf | 2020-07-14 |
| 13 | 201641011533-FORM 4(ii) [11-01-2021(online)].pdf | 2021-01-11 |
| 14 | 201641011533-FER_SER_REPLY [14-04-2021(online)].pdf | 2021-04-14 |
| 15 | 201641011533-CLAIMS [14-04-2021(online)].pdf | 2021-04-14 |
| 16 | 201641011533-Correspondence to notify the Controller [09-07-2021(online)].pdf | 2021-07-09 |
| 17 | 201641011533-Written submissions and relevant documents [27-07-2021(online)].pdf | 2021-07-27 |
| 18 | 201641011533-PatentCertificate28-07-2021.pdf | 2021-07-28 |
| 19 | 201641011533-IntimationOfGrant28-07-2021.pdf | 2021-07-28 |
| 20 | 201641011533-US(14)-HearingNotice-(HearingDate-13-07-2021).pdf | 2021-10-17 |
| 21 | 201641011533-RELEVANT DOCUMENTS [14-08-2023(online)].pdf | 2023-08-14 |
| 1 | SearchE_13-07-2020.pdf |