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A Composition Comprising Hesperitin And Apigenin, And Uses Thereof

Abstract: The present disclosure relates to combination of hesperitin, and apigenin, which in particular w/w ratio range inhibits of DPP7 protein. DPP7 plays a role in retarding the growth of hair follicles, hence inhibiting DPP7 may provide for stimulating hair growth.

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Notices, Deadlines & Correspondence

Patent Information

Application #
Filing Date
31 March 2016
Publication Number
40/2017
Publication Type
INA
Invention Field
CHEMICAL
Status
Email
lsmds@lakshmisri.com
Parent Application
Patent Number
Legal Status
Grant Date
2021-07-28
Renewal Date

Applicants

ITC LIMITED
ITC LIFE SCIENCES & TECHNOLOGY CENTRE #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560 058, India

Inventors

1. HEDGE, Ashok
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
2. KAREMPUDI, Pavani
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India
3. KALSI, Gurpreet
ITC Life Sciences & Technology Centre #3. 1st Main, Peenya Industrial Area, Phase-1, Bangalore 560 058, India

Specification

Claims:1. A composition comprising:
(a) hesperitin; and
(b) apigenin,
wherein hesperitin to apigenin w/w ratio in said composition is in the range of 1:1-9:1.
2. The composition as claimed in claim 1, wherein hesperitin concentration in said composition in the range of 0.00025-0.00045%, and apigenin concentration in said composition in the range of 0.00005-0.00025
%.
3. The composition as claimed in claim 1, wherein hesperitin to apigenin w/w ratio in said composition is 4:1.
4. The composition as claimed in claim 3, wherein hesperitin concentration in said composition is 0.0004%, and apigenin concentration in said composition is 0.0001%.
5. The composition as claimed in claim 1, wherein hesperitin to apigenin w/w ratio in said composition is 1.5:1.
6. The composition as claimed in claim 5, wherein hesperitin concentration in said composition is 0.0003%, and apigenin concentration in said composition is 0.0002%.
7. The composition as claimed in any of the claims 1-6, further comprising suitable diluents, excipients, and carriers.
8. A method to prepare a composition as claimed in any of the claims 1-7.
9. A method to promote hair growth, said method comprising:
(a) obtaining a composition as claimed in any of the claims 1-7; and
(b) contacting said composition with hair follicles,
wherein said method promotes hair growth.

10. A composition as claimed in any of the claims 1-7 for use in preparing topical formulations to promote hair growth.
, Description:As Attached

Documents

Application Documents

# Name Date
1 Sequence listing [31-03-2016(online)].pdf 2016-03-31
2 Form 5 [31-03-2016(online)].pdf 2016-03-31
3 Form 3 [31-03-2016(online)].pdf 2016-03-31
4 Drawing [31-03-2016(online)].pdf 2016-03-31
5 Description(Complete) [31-03-2016(online)].pdf 2016-03-31
6 Other Patent Document [26-05-2016(online)].pdf 2016-05-26
7 Form 26 [26-05-2016(online)].pdf 2016-05-26
8 201641011533-Power of Attorney-300516.pdf 2016-07-22
9 201641011533-Form 1-300516.pdf 2016-07-22
10 201641011533-Correspondence-F1-PA-300516.pdf 2016-07-22
11 201641011533-FORM 18 [27-03-2020(online)].pdf 2020-03-27
12 201641011533-FER.pdf 2020-07-14
13 201641011533-FORM 4(ii) [11-01-2021(online)].pdf 2021-01-11
14 201641011533-FER_SER_REPLY [14-04-2021(online)].pdf 2021-04-14
15 201641011533-CLAIMS [14-04-2021(online)].pdf 2021-04-14
16 201641011533-Correspondence to notify the Controller [09-07-2021(online)].pdf 2021-07-09
17 201641011533-Written submissions and relevant documents [27-07-2021(online)].pdf 2021-07-27
18 201641011533-PatentCertificate28-07-2021.pdf 2021-07-28
19 201641011533-IntimationOfGrant28-07-2021.pdf 2021-07-28
20 201641011533-US(14)-HearingNotice-(HearingDate-13-07-2021).pdf 2021-10-17
21 201641011533-RELEVANT DOCUMENTS [14-08-2023(online)].pdf 2023-08-14

Search Strategy

1 SearchE_13-07-2020.pdf

ERegister / Renewals

3rd: 27 Sep 2021

From 31/03/2018 - To 31/03/2019

4th: 27 Sep 2021

From 31/03/2019 - To 31/03/2020

5th: 27 Sep 2021

From 31/03/2020 - To 31/03/2021

6th: 27 Sep 2021

From 31/03/2021 - To 31/03/2022

7th: 29 Mar 2022

From 31/03/2022 - To 31/03/2023

8th: 14 Mar 2023

From 31/03/2023 - To 31/03/2024

9th: 10 Feb 2024

From 31/03/2024 - To 31/03/2025

10th: 17 Mar 2025

From 31/03/2025 - To 31/03/2026