Abstract: The present disclosure provides a composition comprising of mangiferin, and beta-D-glucan, which at particular w/w ratios exhibits synergistic inhibition of intracellular reactive oxygen species production. Also provided in the present disclosure methods of inhibiting intracellular reactive oxygen species production.
CLIAMS:1. A composition for inhibiting intracellular reactive oxygen species production, said composition comprising:
a. mangiferin; and
b. beta-D-glucan.
2. The composition as claimed in claim 1, wherein mangiferin to beta-D-glucan w/w ratio in said composition is 0.8:1-1.3:1.
3. The composition as claimed in claim 1, optionally comprising of suitable carriers, diluents, and excipients.
4. A method of inhibiting intracellular reactive oxygen species production, said method comprising:
a. obtaining a composition as claimed in claim 1; and
b. contacting said composition with a cell capable of reactive oxygen species production,
wherein said method inhibits intracellular reactive oxygen species production in said cell.
5. A method of preparing a composition as claimed in claim 1.
6. Use of a composition as claimed in claim 1 in inhibiting intracellular reactive oxygen species production.
,TagSPECI:As Attached
| # | Name | Date |
|---|---|---|
| 1 | PD014941IN-SC SPEC FOR FILING.pdf | 2015-03-12 |
| 2 | PD014941IN-SC FORM 5.pdf | 2015-03-12 |
| 3 | PD014941IN-SC FORM 3.pdf | 2015-03-12 |
| 4 | PD014941IN-SC FIGURES FOR FILING.pdf | 2015-03-12 |
| 5 | 308-CHE-2015 POWER OF ATTORNEY 01-05-2015.pdf | 2015-05-01 |
| 6 | 308-CHE-2015 FORM-1 01-05-2015.pdf | 2015-05-01 |
| 7 | 308-CHE-2015 CORRESPONDENCE OTHERS 01-05-2015.pdf | 2015-05-01 |
| 8 | 308-CHE-2015-FORM 18 [04-12-2018(online)].pdf | 2018-12-04 |
| 9 | 308-CHE-2015-FER.pdf | 2020-01-29 |
| 1 | 2020-01-2218-31-56_22-01-2020.pdf |