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Anti Glycation Composition Comprising Phytic Acid, And Hydrangea Macrophylla Extract And Uses Thereof

Abstract: The present disclosure composition comprising phytic acid and Hydrangea macrophylla butylene glycol extract for inhibition of glycation.

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Patent Information

Application #
Filing Date
02 September 2015
Publication Number
09/2017
Publication Type
INA
Invention Field
PHARMACEUTICALS
Status
Email
lsmds@lakshmisri.com
Parent Application

Applicants

ITC LIMITED
ITC Life Sciences and Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560058, India

Inventors

1. AGARWAL, Sakshi
ITC Life Sciences and Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560058, India
2. KHAN, Manisha
ITC Life Sciences and Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560058, India
3. HASSAN, Sarah
ITC Life Sciences and Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560058, India
4. PHULERA, Sumit
ITC Life Sciences and Technology Centre, #3, 1st Main, Peenya Industrial Area, Phase 1, Bangalore 560058, India

Specification

Claims:1. An anti-glycation composition comprising:
a. phytic acid; and
b. Hydrangea macrophylla butylene glycol extract,
wherein phytic acid weight concentration is in the range of 0.0009-0.0011%, and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.0009-0.0011%.

2. The anti-glycation composition as claimed in claim 1, wherein Hydrangea macrophylla butylene glycol extract is obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant and, combinations thereof.

3. The anti-glycation composition as claimed in claim 1, wherein phytic acid weight concentration is in the range of 0.0009-0.0011%, and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.0009-0.0011%.

4. An anti-glycation formulation comprising:
a. phytic acid;
b. Hydrangea macrophylla butylene glycol extract,
wherein phytic acid weight concentration is in the range of 0.0009-0.0011%, and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.0009-0.0011%.

5. The anti-glycation formulation as claimed in claim 4, wherein said Hydrangea macrophylla extract is obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant, and combinations thereof.

6. The anti-glycation formulation as claimed in claim 4 further comprising at least one cosmetically acceptable ingredient.

7. The anti-glycation formulation as claimed in claim 6, wherein said at least one cosmetically acceptable ingredient is selected from the group consisting of suitable carriers, diluents, skin benefitting agents, pH adjusting agents, emollients, moisturizing agent, antimicrobial agents, and excipients.

8. The anti-glycation formulation as claimed in claim 4, phytic acid weight concentration is in the range of 0.0009-0.0011%, and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.0009-0.0011%.

9. A method of preparing an anti-glycation composition comprising phytic acid; and Hydrangea macrophylla butylene glycol extract obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant and, combinations thereof, wherein phytic acid weight concentration is in the range of 0.0009-0.0011% and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.0009-0.0011%.

10. A method of preparing an anti-glycation formulation comprising phytic acid; Hydrangea macrophylla butylene glycol extract obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant and, combinations thereof; and suitable carriers, diluents, and excipients, wherein phytic acid weight concentration is in the range of 0.0009-0.0011% and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.0009-0.0011%.

11. An anti-glycation formulation for topical application comprising:
a. phytic acid having volume percentage of 0.001%;
b. Hydrangea macrophylla butylene glycol leaf extract having volume percentage of 0.001%;
c. acrylates/C10-30 alkyl acrylate cross-polymer having volume percentage of 0.07%;
d. glycerin having volume percentage of 5%;
e. butylene glycol having volume percentage of 2%;
f. D-panthenol having volume percentage of 0.5%;
g. triethanolamine having volume percentage of 0.06%;
h. mineral oil having volume percentage of 4%;
i. cetyl alcohol having volume percentage of 3%;
j. glycol distearate having volume percentage of 3%;
k. dimethicone having volume percentage of 0.5%;
l. allantoin having volume percentage of 0.1%;
m. phenoxyethanol having volume percentage of 0.3%;
n. fragrance having volume percentage of 0.2%; and
o. water having volume percentage of 81.16-81.259%

12. A method for preparing a formulation comprising: a) phytic acid having volume percentage of 0.001%; b) Hydrangea macrophylla butylene glycol leaf extract having volume percentage of 0.001%; c) acrylates/C10-30 alkyl acrylate cross-polymer having volume percentage of 0.07%; d) glycerin having volume percentage of 5%; e) butylene glycol having volume percentage of 2%; f) D-panthenol having volume percentage of 0.5%; g) triethanolamine having volume percentage of 0.06%; h) mineral oil having volume percentage of 4%; i) cetyl alcohol having volume percentage of 3%; j) glycol distearate having volume percentage of 3%; k) dimethicone having volume percentage of 0.5%; l) allantoin having volume percentage of 0.1%; m) phenoxyethanol having volume percentage of 0.3%; n) fragrance having volume percentage of 0.2%; and o) water having volume percentage of 81.16-81.259%.
13. A method for inhibiting glycation, said method comprising the steps:
a. obtaining a composition or a formulation comprising phytic acid; Hydrangea macrophylla butylene glycol extract, obtained from root, leaf, bark, flower, twigs, buds, seeds, wood, whole plant and, combinations thereof, wherein phytic acid weight concentration is 0.001% and Hydrangea macrophylla butylene glycol extract weight concentration is in the range of 0.001%; and
b. contacting said composition or formulation with a site susceptible to glycation,
wherein said method inhibits glycation.
, Description:As Attached

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